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NCT ID: NCT04240691 Active, not recruiting - HIV Infections Clinical Trials

Instacare - Rapid ART Initiation Among Persons With HIV and Out of Care

Start date: May 20, 2020
Phase:
Study type: Observational

This study aims to evaluate two ways to help people re-engage with healthcare. The first is to assess if providing HIV treatment on the first visit (or within 1 week) can help people re-engage with care and ultimately stay in care after 24 and 48 weeks. It will also assess the success of starting treatment immediately by measuring the HIV virus in people's bloodstream after 24 and 48 weeks. The second part of this study is to assess a new behavioral treatment called 60-Minutes-for-Health which aims to help people identify and overcome barriers to HIV care, to help with motivation maintaining in care, to help cope with negative feelings about HIV, and to help increase self-reliance in seeking healthcare amid other things that are happening in your life.

NCT ID: NCT04240639 Active, not recruiting - Clinical trials for Neoplasms of the Prostate

An Extension Study MRI/US Fusion Imaging and Biopsy in Combination With Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue

Start date: January 30, 2020
Phase: N/A
Study type: Interventional

To determine the efficacy of using MRI/US fusion imaging technology to direct focal ablation of prostate tissue using nanoparticle-directed laser irradiation.

NCT ID: NCT04240392 Active, not recruiting - Opioid-use Disorder Clinical Trials

Treatment of Pregnant Women With OUD

SMART
Start date: June 18, 2020
Phase: N/A
Study type: Interventional

The investigators are testing two models of support for pregnant women with an opioid use disorder (OUD)

NCT ID: NCT04240314 Active, not recruiting - Clinical trials for Duchenne Muscular Dystrophy

AAV9 U7snRNA Gene Therapy to Treat Boys With DMD Exon 2 Duplications.

Start date: January 15, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Open-label, single dose clinical trial of scAAV9.U7.ACCA via peripheral limb vein injection for Duchenne muscular dystrophy boys who have a duplication of exon 2.

NCT ID: NCT04239989 Active, not recruiting - Clinical trials for Bronchiolitis Obliterans

Itacitinib for the Treatment of Bronchiolitis Obliterans Syndrome After Donor Hematopoietic Cell Transplant

Start date: April 8, 2021
Phase: Phase 1
Study type: Interventional

This phase I trial studies how well itacitinib works for the treatment of bronchiolitis obliterans syndrome after donor hematopoietic cell transplant. Itacitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

NCT ID: NCT04239911 Active, not recruiting - Heart Failure Clinical Trials

Leveraging Home Health Aides to Improve Outcomes in Heart Failure

Start date: May 16, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to determine the effectiveness of an intervention among home health aides caring for adults admitted to home care with a primary diagnosis of heart failure at VNS Health Partners in Care (home care agency). The study will examine the interventions' effect on home health aides' heart failure knowledge and confidence caring for adults with heart failure, as well as on the client's overall health (visits to the emergency department and hospital readmissions).

NCT ID: NCT04239456 Active, not recruiting - Clinical trials for Traumatic Brain Injury With Loss of Consciousness

Strategy + RehaCom for Memory Rehabilitation in Traumatic Brain Injury (TBI)

REHACOM-NJHF
Start date: December 1, 2018
Phase: N/A
Study type: Interventional

The purpose of this research study is to evaluate the effectiveness of "RehaCom," a computerized treatment for memory deficits, in a 16-session, interactive course. Following a manualized approach, the Rehacom modules will be used for the repeated application of the content acquired during 1-on-1 memory strategy training. The goal is to improve face/name, list and verbal memory of patients who survived a moderate to severe traumatic brain injury.

NCT ID: NCT04239040 Active, not recruiting - Neuroblastoma Clinical Trials

GVAX Plus Checkpoint Blockade in Neuroblastoma

Start date: January 29, 2020
Phase: Phase 1
Study type: Interventional

This research clinical trial is studying the creation and administration of GVAX, an irradiated GM-CSF secreting, autologous neuroblastoma cell vaccine (GVAX) in combination with nivolumab and ipilimumab as a possible treatment for neuroblastoma. The names of the study drugs involved in this study are: - GVAX Vaccine, an immunotherapy developed from surgically removed tumor tissue - Nivolumab - Ipilimumab

NCT ID: NCT04238949 Active, not recruiting - Diabetes Mellitus Clinical Trials

Community Health Workers in Pediatric Patients With Newly Diagnosed Type 1 Diabetes

Start date: December 6, 2019
Phase: N/A
Study type: Interventional

The primary aim of this pilot randomized controlled trial is to determine if the integration of a Community Health Worker (CHW) into the healthcare team of children with newly diagnosed type 1 diabetes is associated with an improvement in diabetes control. The secondary objectives are to determine if utilization of CHWs is also associated with improvements in psychosocial outcomes, healthcare utilization, and decreased costs.

NCT ID: NCT04238819 Active, not recruiting - Clinical trials for Refractory Solid Tumor

A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma

Start date: November 9, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

The study's purpose is to see if the drug, abemaciclib, is safe and effective when given with other drugs to kill cancer cells. The study is open to children and young adults with solid tumors, including neuroblastoma, that did not respond or grew during other anti-cancer treatment. For each participant, the study is estimated to last up to 2 years.