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NCT ID: NCT06098287 Completed - Asthma Clinical Trials

Residential Ventilation Systems and Filtration for Asthma Control in Adults

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The goal of this study was to investigate the effectiveness of three common approaches to upgrading residential mechanical ventilation systems in existing homes for improving asthma-related health outcomes, reducing indoor pollutants of both indoor and outdoor origin, and maintaining adequate environmental conditions and ventilation rates in a cohort of adult asthmatics in existing homes in Chicago, IL.

NCT ID: NCT06097676 Completed - Abuse Potential Clinical Trials

An Abuse Potential Study of Orally Administered HORIZANT in Healthy, Non-dependent, Recreational Drug Users

Start date: September 28, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the abuse potential of gabapentin enacarbil in healthy adult, non-dependent, recreational drug users.

NCT ID: NCT06096077 Completed - Angioedema Clinical Trials

Evaluation of Tranexamic Acid for Angiotensin-converting Enzyme Inhibitor-induced Angioedema in the Emergency Department

Start date: November 30, 2022
Phase:
Study type: Observational

Angiotensin-converting enzyme inhibitor ACEi induced angioedema ACEi-AE is defined as physical swelling of the deep skin layers or mucous membranes due to increased vascular permeability and leakage of fluid into the interstitial space caused while taking an ACEi

NCT ID: NCT06096064 Completed - Clinical trials for Unfractionated Heparin

Medication Use Evaluation (MUE) for Continuous Heparin Infusions in Hospitalized Patients

Start date: October 31, 2022
Phase:
Study type: Observational

Unfractionated heparin (UFH) is an anticoagulant to prevent thrombus formation or worsening of an existing thrombus. It is indicated for patients with deep vein thrombosis/pulmonary embolism (DVT/PE) or acute coronary syndrome (ACS). Unfractionated heparin treatment consists of an initial bolus followed by a continuous infusion that is adjusted based on the patient's subsequent partial thromboplastin time (PTT) levels

NCT ID: NCT06095661 Completed - Surgery Clinical Trials

Virtual Reality as a Postoperative Pain Management Adjunct in Older Adults: An Acceptability and Feasibility Study

VR
Start date: October 26, 2023
Phase: N/A
Study type: Interventional

This single-arm mixed methods study aims to determine potential differences in self-reported postoperative pain intensity levels, anxiety, and state of relaxation through immediate pre-post intervention evaluation among those aged 65 or older who receive immersive virtual reality during their hospitalization, up to three days following major elective surgery. In addition, the investigators will evaluate the feasibility and acceptability of virtual reality for use in this older adult population. This study will not evaluate the efficacy of VR. The main questions this study seeks to answer are: 1. What is the feasibility and acceptability of using immersive virtual reality to impact clinical outcomes such as pain, anxiety, and relaxation in older adults who have undergone major elective surgery? 2. What is the older adult's user experience with virtual reality during hospitalization up to the three days following major elective surgery?

NCT ID: NCT06094790 Completed - Healthy Clinical Trials

A Study to Evaluate the Pharmacokinetics of the Current Capsule Formulation of CORT125134 in Healthy Subjects

Start date: May 18, 2017
Phase: Phase 1
Study type: Interventional

A study designed to characterize the plasma pharmacokinetic (PK) profile of CORT125134 in healthy subjects receiving once-daily oral administration of the current capsule formulation of CORT125134 for 14 days.

NCT ID: NCT06094764 Completed - Thermal Discomfort Clinical Trials

S&B Heat Stress Pilot Protocols

Start date: June 22, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to develop a heat stress program for the construction industry and evaluate its feasibility and appeal.

NCT ID: NCT06094738 Completed - Healthy Clinical Trials

A Study to Evaluate the Effect of Food on the Oral Bioavailability of Relacorilant in Healthy Subjects

Start date: September 19, 2020
Phase: Phase 1
Study type: Interventional

The primary objective of the study is to evaluate the effects of a high-fat meal and of a low-fat meal on the bioavailability of relacorilant in healthy subjects.

NCT ID: NCT06094725 Completed - Hepatic Impairment Clinical Trials

A Study to Evaluate the Effects of Hepatic Impairment on the Pharmacokinetics of Relacorilant

Start date: January 6, 2020
Phase: Phase 1
Study type: Interventional

The primary objective of this multiple-dose, adaptive design study is to evaluate the effect of hepatic impairment on the pharmacokinetics (PK) of relacorilant relative to healthy matched control male and female subjects (Part 1).

NCT ID: NCT06094712 Completed - Healthy Clinical Trials

A Study to Evaluate the Pharmacokinetics of the CORT125134 Phase 2 Formulation in Healthy Male Subjects

Start date: April 7, 2016
Phase: Phase 1
Study type: Interventional

A study designed to characterize the pharmacokinetic (PK) profile of CORT125134 following a single 150-mg oral dose of the Phase 2 capsule formulation of CORT125134 in 8 healthy male subjects.