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NCT ID: NCT05320393 Completed - Clinical trials for Glabellar Frown Lines

Study to Demonstrate Safety and Duration of Effect of 40 Units of PrabotulinumtoxinA-xvfs to Treat Glabellar Lines

Start date: March 30, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to demonstrate the safety and duration of effect of 40 Units of prabotulinumtoxinA-xvfs (Jeuveau®) in providing temporary improvement in the appearance of moderate to severe glabellar lines (frown lines, which are the vertical lines that develop between the eyebrows) in adult participants. It will also determine if the duration of effect of 40 Units of Jeuveau® is greater than that of 20 Units of Jeuveau® and 20 Units of Botox® Cosmetic.

NCT ID: NCT05320289 Completed - Clinical trials for Polycystic Ovary Syndrome

Feasibility Study of the AblaCare System in Transvaginal Ablation of Ovarian Tissue Under ULTRAsound Visualization in Women With Infertility Due to Polycystic Ovary Syndrome

ULTRA-US
Start date: May 12, 2022
Phase: N/A
Study type: Interventional

The objective of the study is to provide preliminary evidence for the safety and effectiveness of the AblaCare System in transvaginal ablation of ovarian tissue under ultrasound visualization in women with infertility due to polycystic ovary syndrome (PCOS) who have not responded to first-line ovulation induction treatment or are contraindicated for or decline such treatment.

NCT ID: NCT05320159 Completed - Psoriasis Clinical Trials

Treatment Effectiveness Among Psoriasis Patients Treated With Cosentyx (Secukinumab)

Start date: February 3, 2021
Phase:
Study type: Observational

This was a retrospective cohort study utilizing data from Modernizing Medicine Data Services' (MMDS) electronic medical records (EMR)-based dermatology database to evaluate secukinumab patient characteristics, treatment patterns, and outcomes.

NCT ID: NCT05320094 Completed - Clinical trials for Healthy Participants

A Study to Evaluate the Effect of Activated Charcoal With Sorbitol on the Single-dose of Mavacamten in Healthy Participants

Start date: April 15, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the effects of co-administration of activated charcoal with sorbitol on the single-dose drug levels of mavacamten in healthy participants.

NCT ID: NCT05320042 Completed - Myopia Clinical Trials

1-Week Dispensing Evaluation of Kalifilcon A Toric Contact Lenses Compared to Ultra for Astigmatism

Start date: February 14, 2022
Phase: N/A
Study type: Interventional

Experienced soft contact lens wearing subjects will be enrolled in this 1-week, confirmatory, randomized, bilateral, 2-way crossover, double masked (subject and investigator), repeated measures, dispensing study. All subjects will be seen for a Screening/Baseline Visit at which informed consent will be obtained and eligibility will be assessed.

NCT ID: NCT05319912 Completed - Healthy Clinical Trials

A Study of ALXN1840 (Coated and Non-coated) Administered With And Without Omeprazole In Healthy Adults

Start date: April 7, 2014
Phase: Phase 1
Study type: Interventional

This was single-center, open-label, randomized, 3-period, 3-treatment, 6-sequence crossover study evaluating the PK of single doses of WTX101 in healthy participants based on the measurement of plasma total Mo concentration.

NCT ID: NCT05319899 Completed - Healthy Clinical Trials

A Study of ALXN1840 (Non-coated) Administered With And Without Omeprazole In Healthy Adults

Start date: January 20, 2014
Phase: Phase 1
Study type: Interventional

This was single-center, open-label, randomized, 3-period, 3-treatment, 6-sequence crossover study evaluating the PK of single doses of WTX101 in healthy participants based on the measurement of plasma total Molybdenum.

NCT ID: NCT05319860 Completed - Clinical trials for Chemotherapy-induced Nausea and Vomiting

Aromatherapy for Chemotherapy-induced Nausea and Vomiting (CINV)

Start date: August 1, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the use of aromatherapy to reduce nausea, vomiting, and the use of anti-emetic in cancer survivors undergoing moderate to highly emetogenic chemotherapy regimens.

NCT ID: NCT05319847 Completed - Acne Clinical Trials

An Exploratory Investigation of a Male Focused Skincare Supplement

Start date: April 15, 2022
Phase: N/A
Study type: Interventional

Most skincare products on the market are topical and do not take a holistic approach to understanding skin health. This trial will examine a dietary supplement designed to support the gut microbiome and promote skin health from an internal perspective. Research has previously supported the link between the gut microbiome and skin health and the supplement tested in this trial will further the knowledge on the effectiveness of supporting gut health to improve skin outcomes.

NCT ID: NCT05319756 Completed - Abuse Potential Clinical Trials

Study Evaluating the Abuse Potential of NEURONTIN® in Healthy Non-drug Dependent, Recreational Opioid Users

Start date: April 30, 2021
Phase: Phase 4
Study type: Interventional

This will be a randomized, double-blind, double-dummy, placebo- and active-controlled, 6 treatment, 6-period crossover single-dose, Williams square design study in healthy male and/or female adult, non-drug-dependent recreational opioid users.