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NCT ID: NCT06293937 Not yet recruiting - Weight Prejudice Clinical Trials

Impact of Front-of-package Labels on Weight Bias Among Latines

Start date: May 27, 2024
Phase: N/A
Study type: Interventional

The goal of this experiment is to examine the effects on explicit weight bias of a selection task using 4 different types of front-of-package food labels to select healthy or unhealthy foods among a sample of Latine and low English proficiency adults. The main questions this experiment aims to answer are: - Does the use of different front-of-package label designs in a selection task lead to different effects on explicit weight bias among Latine and low English proficiency consumers? - Does the use of different front-of-package label designs in a selection task lead to different effects on attribution of personal responsibility for body weight among Latine and low English proficiency consumers? Participants will be randomly assigned to 1 of 4 types of front-of-package label designs. They will view 3 sets of products (frozen meals, frozen pizzas, and frozen desserts), shown in random order. For each product set, participants will view 3 products shown in random arrangement, each with participants' randomly assigned label shown on the front of package. After viewing all 3 product types, participants will answer questions about explicit weight bias and attribution of responsibility for body weight. Researchers will compare results across label designs.

NCT ID: NCT06293898 Recruiting - Ovarian Cancer Clinical Trials

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

Start date: February 9, 2024
Phase: Phase 1
Study type: Interventional

The objective of this study is to evaluate the safety, tolerability, and efficacy of BL-M07D1 in patients with HER2 expressing advanced tumors.

NCT ID: NCT06293846 Recruiting - Women's Health Clinical Trials

BeFit Toolbox Collaboration: Building Empowerment Through Fitness

BEFIT
Start date: March 15, 2024
Phase: N/A
Study type: Interventional

This project will identify the causative behavioral factors in low-income African American women leading to sedentarism, a major source of morbidity in HABD communities. Working with our partner, WUCN, we will engage with women in HABD housing to develop and (later) deliver a physical activity education program (BeFit) customized for this population.

NCT ID: NCT06293820 Recruiting - Clinical trials for Allergic Conjunctivitis

A Study Of TL-925 For The Treatment of AC

Start date: March 2024
Phase: Phase 2
Study type: Interventional

In this prospective, Phase 2, randomized, double-masked, vehicle controlled study, approximately 70 eligible subjects will be randomized 1:1 to receive either TL-925 or placebo as topical ophthalmic eye drops administered bilaterally. The study comprises of a screening and treatment period using the conjunctival allergen challenge model to evaluate TL-925 for the treatment of allergic conjunctivitis.

NCT ID: NCT06293807 Completed - Clinical trials for Periodontal Diseases

Immediate Post-Operative Anesthesia With Either Lidocaine or Bupivacaine

Start date: June 6, 2022
Phase: Early Phase 1
Study type: Interventional

Immediate post-suturing administration of either one of two dental anesthetic solutions or a placebo prior to dismissal.

NCT ID: NCT06293742 Recruiting - Clinical trials for Type 2 Diabetes Mellitus

ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy Participants

Start date: February 9, 2024
Phase: Phase 1
Study type: Interventional

This is a Phase 1, open-label, non-randomized, fixed sequence study designed to evaluate the effect of ECC5004 on single dose pharmacokinetics of Atorvastatin, Rosuvastatin, Digoxin and Midazolam in healthy participants.

NCT ID: NCT06293703 Recruiting - Morbid Obesity Clinical Trials

Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study)

CLIMB II
Start date: January 12, 2024
Phase: N/A
Study type: Interventional

The investigators propose a randomized controlled trial comparing BP and roux limb lengths measuring 30 and 15% respectively of patient's total small bowel length versus current standard practice using fixed lengths. The findings would provide further insight into feasibility of standardizing RYGB limb lengths and optimizing resultant weight loss and metabolic effects. The investigators hypothesize RYGB with ratio-adjusted limb lengths (aRYGB) will result in higher total weight loss and resolution of metabolic syndrome comorbidities, including diabetes, hyperlipidemia, and hypertension compared to standard fixed-length RYGB (sRYGB). The study will also utilize the Short Form Rand 36-Item Health Survey (SF36) to determine differences in postoperative quality of life metrics.

NCT ID: NCT06293638 Recruiting - Essential Tremor Clinical Trials

Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor

TRaNCE
Start date: March 25, 2024
Phase:
Study type: Observational

The purpose of this study is to collect electrophysiological data related to functional brain network changes in patients undergoing deep brain stimulation for the treatment of essential tremor. Participants will be asked to remain seated with their head inside of a Magnetoencephalography (MEG) recording system as resting-state and task-related data are acquired. Spontaneous electrophysiological activity will be recorded in both the eyes open and eyes closed conditions with the participant seated comfortably. These recordings will be repeated in the DBS OFF and DBS ON states, with the ON state involving specific settings identified as optimal, sub-optimal, or ineffective at achieving tremor control. They will also be repeated following the optional administration non-DBS tremor mitigation techniques, which may include one or more of 1) cooling the limb, 2) oral administration of alprazolam, 3) oral consumption of ethanol (alcohol), or 4) peripheral nerve stimulation.

NCT ID: NCT06293560 Recruiting - Coloboma Clinical Trials

Microphthalmia, Anophthalmia, and Coloboma Genetic Epidemiology in Children

MAGIC
Start date: September 25, 2022
Phase:
Study type: Observational

The investigators are inviting families to take part in a research study that will help us better understand the physical characteristics associated with children who have Microphthalmia, Anophthalmia, and Coloboma (MAC) and how changes in their DNA sequence, called genetic mutations, play a role in the risk of developing MAC

NCT ID: NCT06293482 Not yet recruiting - Clinical trials for Hearing Loss, Sensorineural

Safety and Effectiveness of Cochlear Implantation in an Expanded Adult Population

ACE
Start date: July 2024
Phase: N/A
Study type: Interventional

This study aims to evaluate the safety and efficacy of cochlear implantation for adults with bilateral sensorineural hearing loss who currently do not meet the FDA-approved indications for cochlear implantation. Following cochlear implantation, participants will complete speech perception assessments and questionnaires over the course of seven visits.