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Morbid Obesity clinical trials

View clinical trials related to Morbid Obesity.

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NCT ID: NCT03692455 Completed - Morbid Obesity Clinical Trials

Clinico-functional Evaluation of GERD: Comparative Study of Vertical Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass

Start date: October 19, 2016
Phase: N/A
Study type: Interventional

The hypothesis of this study is that surgical techniques primarily designed for weight loss, ameliorates gastroesophageal reflux disease (GERD) in morbidly obese patients. Therefore the present study intends to evaluate such impact on patients submitted to two of the most common techniques available, the Roux-en-Y Gastric Bypass and Vertical Sleeve Gastrectomy.

NCT ID: NCT03666481 Completed - Morbid Obesity Clinical Trials

Physical Activity in Bariatric Patients

Start date: November 16, 2011
Phase: N/A
Study type: Interventional

The aim of the current study was to explore the effect of a 6-months motivational physical activity intervention (MPAI) on different psychosocial variables (e.g. motivation, health-related quality of life, self-esteem, etc.) and on the physical activity levels of bariatric surgery patients. Comparing with a control group (CG), we tested the differences obtained on these variables between before surgery and just after the MPAI (7-months after surgery). Additionally, we explored the (possible) prolonged effects of the intervention by doing re-tests 13, 25 and 37- months after surgery.

NCT ID: NCT03657927 Active, not recruiting - Morbid Obesity Clinical Trials

A Comparison of McGrath Versus C-MAC Videolaryngoscopes in Morbidly Obese Patients

mcgrath&cmac
Start date: August 7, 2018
Phase: N/A
Study type: Interventional

Along with the technological advances in medicine, videolaryngoscope is the most commonly preferred technique for intubation of expected difficult airway management such as morbidly obese patients. In this prospective controlled clinical study, the purpose is to compare C-MAC videolaryngoscope and McGrath videolaryngoscope in respect to duration of intubation, haemodynamic response, and complications related intubation of morbidly obese patients undergoing bariatric surgery.

NCT ID: NCT03601273 Not yet recruiting - Obesity Clinical Trials

Bariatric Embolization Trial for the Obese Nonsurgical

BET-ON
Start date: September 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the safety profile of bariatric embolizations and confirm published reports of sustained post-procedural weight loss, and pathologically assess post-procedural metabolic effects.

NCT ID: NCT03590951 Completed - Morbid Obesity Clinical Trials

Anesthetic and Obstetric Outcomes in Morbidly Obese Pregnancy and Cesarean Delivery

Start date: May 3, 2017
Phase:
Study type: Observational

Given that morbid obesity has been strongly associated with obstetric, neonatal and anesthetic complications, and that scarce reports have evaluated anesthetic and obstetric outcomes after cesarean delivery in morbidly obese patients; This study retrospectively analyzed anesthetic, obstetric and neonatal outcomes in morbidly obese pregnant patients who underwent cesarean delivery at Augusta University Medical Center, during a 2-year period (2015-2016).

NCT ID: NCT03559842 Recruiting - Morbid Obesity Clinical Trials

Sleeve-gastrectomy Efficacy in Morbid Obese Patient With a Focus on the Role of Inflammation

Start date: May 4, 2017
Phase:
Study type: Observational

Despite the wide range of studies concerning the positive effects of bariatric surgery on metabolic state of morbid obese patient, it is necessary to further investigate the specific role of the "sleeve-gastrectomy" intervention, going not only to research results in terms of safety or efficacy on the treatment of comorbidities, but also aimed to understand whether the improvement of metabolic and cardiovascular parameters is due to total weight loss or rather to visceral fat loss, and how much of this improvement is attributable to changes in inflammatory status. The primary endpoint of the study is to evaluate the effect of sleeve-gastrectomy on metabolic parameters (glyco-lipidic assessment, vitamins), bone-remodelling parameters (vitamin D, parathormone) and cardiovascular parameters (blood pressure, flow-mediated dilation, indexed left ventricular mass, inter-ventricular septum, carotid intima-media thickness) in a large obese population on the basis of total weight loss (TWL), variation of visceral fat area (VFA), variation of peri-renal fat thickness and insulin resistance index ("Homeostasis Model Assessment-insulin resistance" - HOMA). In addition the investigators set themselves the objective of assessing whether the presence of comorbidities (diabetes and hypertension) can influence the effects of the intervention on the above parameters, and whether the levels of the NETs and of adipokines such as chemerin in the pre- and post-intervention can correlate with the metabolic-vascular dysfunction, and play a role in its eventual improvement.

NCT ID: NCT03554902 Recruiting - Morbid Obesity Clinical Trials

Endoscopic Gastric Tubulization

Endosleeve
Start date: June 8, 2018
Phase:
Study type: Observational

Endoscopic gastric tubulization is currently proposed in the Digestive Surgery Department of the Nouvel Hôpital Civil, Strasbourg, France, to adult patients with morbid obesity. The procedure is performed using the CE marked endoscopic suture device Overstitch (Apollo Endosurgery, Austin, Tx. USA). It is standard practice since October 2016. The objective of this study is to prospectively collect data of patients who underwent an endoscopic gastric tubulization, from last visit before procedure to 2 years after procedure. These data are usually collected during medical consultations and will enable the evaluation of weight loss, quality of life and comorbidities improvement, reproducibility and durability of the technique.

NCT ID: NCT03553849 Recruiting - Morbid Obesity Clinical Trials

Utilization of Very Low Calorie Diet in Obese General Surgery Patients

Start date: September 24, 2018
Phase: N/A
Study type: Interventional

The investigators are studying the use of a two-week very low calorie diet (VLCD) in obese general surgery patients in a randomized single-blinded trial. The investigators hypothesize that the VLCD will positively impact the perceived surgical difficulty, operative time, hospital length of stay and 30-day complications. Additionally, the investigators anticipate reduced perioperative blood glucose levels and a reduced need for perioperative insulin administration.

NCT ID: NCT03517072 Recruiting - Morbid Obesity Clinical Trials

Determinants of the Long-Term Success of Bariatric Surgery

PRECOS
Start date: July 31, 2018
Phase:
Study type: Observational

The management of obesity is based on a multidisciplinary approach and justifies the use of surgery in patients with the most severe forms. Surgery for obesity or bariatric surgery generally allows rapid and significant weight loss however it is associated with significant risks, and its long-term results remain heterogeneous and unpredictable. Long-term data will clarify the role of different types of bariatric surgery in surgical strategy, improve patient information and identify predictors of failure in order to provide personalised and tailored surgery for each candidate .

NCT ID: NCT03467048 Recruiting - Morbid Obesity Clinical Trials

McGrath Videolaryngoscopy and Direct Laryngoscopy in Morbidly Obese Patients

Start date: July 24, 2018
Phase: N/A
Study type: Interventional

Our goal is to compare conventional direct laryngoscopy using a Macintosh blade with the McGrath videolaryngoscope for endotracheal intubation in very morbidly obese patients undergoing non-cardiac surgery. Specifically, we propose to test the primary hypotheses that videolaryngoscopy improves visualization of the vocal cords, defined with modified Cormack and Lehane classification, compared to direct laryngoscopy.