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Morbid Obesity clinical trials

View clinical trials related to Morbid Obesity.

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NCT ID: NCT03429205 Not yet recruiting - Morbid Obesity Clinical Trials

The Efficacy of External Warming During Laparoscopic Bariatric Surgery

Start date: April 2018
Phase: N/A
Study type: Interventional

External warming is routinely used in general surgery to offset the deleterious effects of hypothermia. It entails deployment of a disposable, external heating blanket attached to a regulated hot-air pump. The need for external warming in the morbidly obese population undergoing short laparoscopic procedures is unclear. If proven to be unnecessary, time and momentary costs could be lowered. The study will compare core-temperature dynamics during laparoscopic bariatric procedures anticipated to last <2h. The study group will be left without a warming blanket while the control group will receive routine external warming. Post-anesthesia care unit (PACU) arrival temperature will also be recorded.

NCT ID: NCT03428386 Recruiting - Morbid Obesity Clinical Trials

Single-Anastomosis Plication Ileal Bypass for Morbid Obesity

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

The present study aims to explore the impact of combining laparoscopic greater curvature plication with a single gastro-ileal anastomosis in the same manner of single anastomosis sleeve ileal bypass on weight loss and postoperative complications. The objective of this combined procedure is to reduce the high intraluminal pressure that results after laparoscopic greater curvature plication owing to reduced intraluminal space which can lead to suture line leakage, vomiting, and gastroesophageal reflux disease. Another objective is to add a malabsorptive element to the restrictive effect of laparoscopic greater curvature plication and to induce early satiety in patients by distention of the distal bowel with nutrients immediately after meals, similar to the way that single anastomosis sleeve ileal bypass works.

NCT ID: NCT03419104 Not yet recruiting - Morbid Obesity Clinical Trials

Preoperative Exercise Test and Postoperative Intensive Care Unit Need in Bariatric Surgery

Start date: February 20, 2018
Phase: N/A
Study type: Interventional

The aim of our study is to evaluate the efficacy of "60 meters 60 seconds exercise test" (a test designed by the study group) done preoperatively as a predictor test for postoperative intensive care unit need and extubation success in patients undergoing bariatric surgery.

NCT ID: NCT03411772 Recruiting - Morbid Obesity Clinical Trials

Trial on TAP Block After Bariatric Surgery

Start date: January 10, 2018
Phase: N/A
Study type: Interventional

Patients undergoing bariatric surgery will be divided randomly into two groups: the first will have TAP block upon completion of surgery and the second groups will not have TAP block.

NCT ID: NCT03410849 Recruiting - Morbid Obesity Clinical Trials

Long-term Adverse Effects After Bariatric Surgery on Oesophagus Epithelium

FUB-B
Start date: February 1, 2018
Phase: N/A
Study type: Interventional

The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on oesophageal symptoms and disease, including the presence of Barrett oesophagus ≥ 5 years post-surgery.

NCT ID: NCT03410459 Recruiting - Morbid Obesity Clinical Trials

Long-term Adverse Effects After Bariatric Surgery on Bone Density

FUB-A
Start date: February 1, 2018
Phase: N/A
Study type: Interventional

The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on bone mineral density, fracture risk, and body composition ≥ 5 years post-surgery.

NCT ID: NCT03384303 Completed - Morbid Obesity Clinical Trials

Changes in Incretines, Gut Hormones and Bile Acids After Roux-en-Y Gastric Bypass

Start date: October 1, 2015
Phase: N/A
Study type: Interventional

Obesity is an increasing world wide problem. Moreover, the increase in patients who are considered morbidly obese is even higher (Sturm et al, Healt Aff 2004). Conservative approaches such as diets or medication are unsuccessful in the majority of the patients. Additionally, (morbid) obesity leads often to cardiovascular diseases, such as hypertension, dyslipidemia and type 2 diabetes (T2DM). When patients need insulin to regulate their glucose levels, their weight is even more difficult to control. Therefore, bariatric procedures are increasingly performed, with over 8.000 procedures in the Netherlands in 2013. The two most performed types of bariatric surgery in the Netherlands are the Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) and the Laparoscopic Sleeve Gastrectomy (LSG). Within the LRYGB there are different variants available. In a recently initiated randomized controlled trial (RCT) from our centre, a comparison between two variants of RYGB was performed. In this RCT our standard RYGB (s-RYGB:alimentary limb (AL) of 150cm; biliopancreatic limb (BPL) of 75cm) was compared with a RYGB with an long BPL (LBPLRYGB:AL of 75cm and a BPL of 150cm). A LBPLRYGB might improve weight loss and reduction after surgery. The exact mechanism of action is still not fully understood. Stomach volume is decreased and satiety levels often increase, probably due to changes in incretin levels. Passage of foods through the gastrointestinal tract are altered after RYGB. A possible explanation might be found in different levels of incretins (such as GLP-1, PYY and ghrelin) and bile acids (FGF-19 and FGF-21) after bariatric surgery.

NCT ID: NCT03306771 Not yet recruiting - Metabolic Syndrome Clinical Trials

The Relationship Between Morbid Obesity and Carotid Artery Stenosis

Start date: December 2017
Phase: N/A
Study type: Observational

The correlation between metabolic syndrome and carotid artery stenosis is well established. The purpose of this study is to evaluate the relationship between morbid obesity and carotid artery stenosis.

NCT ID: NCT03305432 Recruiting - Morbid Obesity Clinical Trials

Preoperative PPI in Sleeve Gastrectomy

Start date: January 15, 2018
Phase: Phase 2
Study type: Interventional

he purpose of this study is to study the effect of preoperative PPI in the early outcome of sleeve gastrectomy

NCT ID: NCT03283644 Active, not recruiting - Obesity Clinical Trials

Obesity-related Inflammation in Patients Prior to and After Bariatric Surgery

Start date: June 2015
Phase: N/A
Study type: Observational

This study investigates the chronic long-term health condition of obesity and its effect on neutrophil function and the inflammatory response