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NCT ID: NCT04056299 Terminated - Hen Egg Allergy Clinical Trials

Oral Immunotherapy for Desensitization in Children, Adolescents, and Young Adults With Hen Egg Allergy

Start date: August 20, 2019
Phase: Phase 2
Study type: Interventional

To determine the efficacy and safety of AR201 in a characterized oral desensitization immunotherapy (CODITâ„¢) regimen in hen egg-allergic subjects aged 4 to 26 years, inclusive.

NCT ID: NCT04055168 Terminated - Dyslipidemia Clinical Trials

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD6615 in Healthy Subjects

Start date: July 24, 2019
Phase: Phase 1
Study type: Interventional

This study will be a randomized, single-blind, placebo-controlled, single-ascending dose (SAD), sequential group study. It is a SAD study in healthy Non-Asian subjects (Part 1) and healthy Japanese subjects (Part 2) to assess the safety and tolerability of AZD6615 and to characterize the pharmacokinetics (PK) of AZD6615.

NCT ID: NCT04054141 Terminated - ALS Clinical Trials

rTMS in Treatment of Spasticity

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

This is an open-label clinical trial to determine the safety and efficacy of rTMS in reducing spasticity and improving quality of life among patients with upper motor neuron predominant motor neuron disease (MND).

NCT ID: NCT04053543 Terminated - PAH Clinical Trials

CXA-10 Study in Subjects With Pulmonary Arterial Hypertension

Start date: August 9, 2019
Phase: Phase 2
Study type: Interventional

This is a Phase 2, multicenter, open-label extension (OLE) of study CXA-10-301, to evaluate the long term safety and efficacy of daily dosing of CXA-10.

NCT ID: NCT04053452 Terminated - Clinical trials for Guillain-Barre Syndrome

Peripheral Nerve Ultrasound for Diagnosis and Prognosis of Guillain-Barre Syndrome

Start date: September 30, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if peripheral nerve ultrasound can be used as a supplemental tool to diagnose Guillain-Barre syndrome (GBS) in the acute setting and aid in prognostication.

NCT ID: NCT04053309 Terminated - Clinical trials for Male Infertility Due to Azoospermia

Round Spermatid Injection Protocol

ROSI
Start date: August 16, 2019
Phase:
Study type: Observational

To evaluate embryology outcomes after application of a technique known as round spermatid injection (ROSI) into donor oocytes in a high-volume clinical infertility practice.

NCT ID: NCT04052347 Terminated - Pregnancy Related Clinical Trials

Decision Aid to Assist Low-Risk Nulliparous Women Considering Induction of Labor At 39 Weeks

DAWN
Start date: November 25, 2019
Phase: N/A
Study type: Interventional

The primary objective is to assess if the utilization of a decision-aid increases the likelihood of low-risk nulliparous women undergoing elective induction of labor at 39.0-39.6 weeks

NCT ID: NCT04052204 Terminated - Clinical trials for Squamous Cell Carcinoma of the Head and Neck (SCCHN)

Avelumab With Bempegaldesleukin With or Without Talazoparib or Enzalutamide in Advanced or Metastatic Solid Tumors

Start date: December 30, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

Evaluation of the combination of avelumab + bempegaldesleukin (NKTR-214 ) in locally advanced squamous cell carcinoma of the head and neck ( metastatic SCCHN) and avelumab + bempegaldesleukin (NKTR-214) + talazoparib or enzalutamide in metastatic castration resistant prostate cancer (mCRPC).

NCT ID: NCT04051996 Terminated - Clinical trials for ACUTE MYELOID LEUKEMIA

GLAD-AML - Glasdegib (Pf-04449913) With Two Standard Decitabine Regimens for Older Patients With Poor-risk Acute Myeloid Leukemia

Start date: December 6, 2019
Phase: Phase 2
Study type: Interventional

This multi-center, randomized phase 2 study is designed to evaluate the complete remission (including complete remission with incomplete count recovery) rates of glasdegib in combination with either decitabine on a 5-day or 10-day schedule in patients with newly-diagnosed poor-risk AML who either refuse or are ineligible for intensive therapy.

NCT ID: NCT04051957 Terminated - Hypertension Clinical Trials

Isosorbide Mononitrate For Anti-Vascular Endothelial Growth Factor (VEGF) Induced Kidney Injury

Start date: September 26, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the hypothesis that isosorbide mononitrate prevents deterioration of renal function in patients receiving anti-angiogenic therapies that target vascular endothelial growth factor (VEGF).