There are about 15072 clinical studies being (or have been) conducted in Turkey. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
This study is an open-label study to evaluate the safety of long-term administration of inclacumab in participants with sickle cell disease (SCD). Participants in this study will have completed a prior study of inclacumab.
This study will assess the efficacy and safety of capivasertib plus docetaxel versus placebo plus docetaxel in participants with metastatic castration resistant prostate cancer (mCRPC), all participants will receive the docetaxel with steroid therapy and receive androgen deprivation therapy. The intention of the study is to demonstrate that the combination of capivasertib plus docetaxel is superior to placebo plus docetaxel with respect to the overall survival of study participants, when overall survival is defined as the time from randomization until the date of death due to any cause.
Investigators aim to investigate the changes in patients' quality of life with different type of seton application.
Ruptured endometrioma cases were compared with unruptured endometrioma cases.
The purpose of the study was to compare the fetal thymus volumes of 18-24-week pregnant women with In Vitro Fertilization (IVF) and spontaneous pregnant women.
In this study, it was planned to evaluate the preoperative neck ultrasonography measurements as a predictor of difficult airway in adult patients who will undergo elective surgery under general anesthesia.
The purpose of this study to evaluate the clinical efficacy of guselkumab in fistulizing, perianal Crohn's disease and to assess the overall safety of guselkumab.
A growing body of research has revealed the good psychometric properties and three-component factor structure of DEPS-R in children and adolescents with type 1 diabetes (T1D) but research with adults has limited and has differing results. The Diabetes Eating Problem Survey-Revised (DEPS-R) developed by Markowitz et al is a diabetes-specific self-report instrument to screen eating disorders for individuals with T1D. DEPS-R is a 16-item diabetes-specific self-report questionnaire to test for diabetes-specific eating disorders. Answers are scored on a six-point Likert scale, with higher scores indicating more DEB and a total score of ≥20 indicating a high risk for eating disorders (range 0-80). The original DEPS-R has been shown to have a good internal consistency (Cronbach's alpha=0.86) and construct validity in a sample of the pediatric population with T1D. This study aimed to evaluate the validity and reliability of the Turkish version of the DEPS-R questionnaire for adults with T1D, investigate its psychometric properties and factor structure, and examine its relationship with the EDE-Q questionnaire.
The fact that Basic Life Support (BLS) training is factor determining survival necessitates the dissemination of BLS training. However, the fact that BLS training increases the workload of trainers and requires cost is one of the most important obstacles to the dissemination of this training. The search for new training methods with high efficiency and low cost continues in BLS training. Global guidelines recommend increasing quality of BLS and autonomous learning on BLS, and also encourage studies to develop methods related to this. The use of e-training methods in BLS training is reported to be cost-effective as well as reducing the burden of trainers. In studies investigating the effectiveness of e-learning methods in BLS training, simulation models with feedback were used to evaluate psychomotor skills of the training. In this study, it was evaluated that it would be beneficial to apply a blended e-learning method, which includes video demonstrations of theoretical and BLS psychomotor skills, to nursing students in a virtual classroom environment. In evaluation of the psychomotor skills of BLS training, it was thought that a simple simulation model (Tshirt Dressed Simulation Pillow (TDSP)) could be created in home environment by wearing the tshirt with the sternum and heart print on a standard pillow (40 X 60 cm) in the student's home. It is thought that psychomotor skills will be improved with repetitive BLS applications that students will make on this model in the home environment. Two weeks after blended training, the BLS application will be made and evaluated on the real model. This training and assessment method is a new method that will allow the evaluation of BLS knowledge and the development of psychomotor skills with autonomous learning, and the fact that there is no study on this subject in the literature constitutes the original value of this study. In this study, it is aimed to evaluate effects of the blended e-training method and TDSP model given to nursing students on the cognitive and psychomotor learning outcomes of the students on BLS. The research is a randomized, controlled pilot study in a quasi-experimental design to be conducted at Hasan Kalyoncu University, Faculty of Health Sciences, Department of Nursing. The study was approved by Hasan Kalyoncu University Health Sciences Non-Interventional Research Ethics Committee. Written permission will be obtained. Before starting the study, the aims and objectives of the research will be explained to the students, information will be given about the blended e-learning method to be applied in the research, what the students should do within the scope of the research and data collection methods. Written and verbal consent will be obtained from the students who volunteered to participate in the study. The population of the research will be students (N=387) studying at Hasan Kalyoncu University, Faculty of Health Sciences, Department of Nursing in the 2021-2022 academic year. Students who have received BLS training for the first time, who have not practiced BLS before, and who voluntarily agree to participate in the study will be included in the study. The number of samples was determined as n=62 by power analysis. Students who accept to participate will be randomly divided into two groups through the computer program. The data collection tool consists of two forms, the form consisting of the introductory information of the students and the evaluation form of BLS knowledge and skills. The answers given to the cognitive questions and psychomotor skills of the nursing students in the study and control groups in the pre-test and post-test will be compared with appropriate statistical methods. A value of P<0.05 will be accepted for statistical significance.
The aim of the study is to investigate the acute effects of trampoline exercises on balance, proprioception, vertical jump and cognitive functions. As a result of the study, it is thought that trampoline exercises will affect balance, proprioception, vertical jump, cognitive functions and myotonometric properties of the muscle more positively than walking.