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NCT ID: NCT06184074 Recruiting - Breast Cancer Clinical Trials

Effect of Aromatase Inhibitors on Ultrasonographic Measurements and Static and Dynamic Balance Scores in Breast Cancer

Start date: February 1, 2024
Phase:
Study type: Observational

To evaluate the effects of aromatase inhibitors on lower extremity ultrasonographic measurements, static and dynamic balance scores in breast cancer patients using aromatase inhibitors

NCT ID: NCT06183931 Recruiting - Clinical trials for Transthyretin Amyloid Cardiomyopathy

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM

DepleTTR-CM
Start date: January 11, 2024
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to assess the efficacy of ALXN2220 in the treatment of adult participants with ATTR-CM by evaluating the difference between the ALXN2220 and placebo groups as assessed by the composite endpoint of all-cause mortality (ACM) and total cardiovascular (CV) clinical events.

NCT ID: NCT06183541 Recruiting - Pain, Postoperative Clinical Trials

Effects of Pericapsular Nerve Group Block Applied in Patients Undergoing Hip Fracture Surgery.

Start date: November 21, 2023
Phase: N/A
Study type: Interventional

In this study, it was aimed to compare the multimodal analgesia application or the pericapsular nerve group (PENG) block methods in patients undergoing hip surgery. The effectiveness and benefit rate of the PENG block in postoperative pain will be evaluated. Postoperative pain, need for additional analgesia, range of motion of the hip joint, mobilization time, length of hospital time and adverse events in patients undergoing hip fracture surgery with and without PENG block will be investigated.

NCT ID: NCT06183528 Recruiting - Analgesia Clinical Trials

Effects of Pericapsular Nerve Group Block on Postoperative Recovery for Total Hip Arthroplasty

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

The hypothesis of this study is that patients who undergo PENG block in before Total Hip Artroplasthy (THA) surgery with spinal anesthesia will have reduced postoperative pain scores, less need for opioid analgesics and earlier mobilisation.

NCT ID: NCT06183424 Recruiting - COVID-19 Clinical Trials

TDCS Stimulation After Covid-19 Infection

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

In this study, the effects of bilateral stimulation of the dorsolateral prefrontal cortex (DLPFC) with active tDCS (transcranial direct stimulation/transcranial direct stimulation) on neurocognitive (memory and executive) functions in patients with Covid-19 infection and subjective cognitive complaints, as well as resting-state fMRI In the case of dfMRI, it is aimed to examine the default mode network (DMN) and parietal memory network (PMN) inter- and intra-network connectivity alterations and the hippocampal region connectivity alterations and contribute to the relevant literature.

NCT ID: NCT06183164 Recruiting - Clinical trials for Breast Cancer Patients Receiving Chemotherapy

Awareness Based Stress Reduction Program Applied to Breast Cancer Patients Receiving Chemotherapy

Mindfulness
Start date: December 29, 2023
Phase: N/A
Study type: Interventional

Implementation of awareness-based stress reduction program in breast cancer patients receiving chemotherapy and examining its effects on psychological resilience, symptom management and quality of life.

NCT ID: NCT06183021 Recruiting - Pain, Postoperative Clinical Trials

The Effect of Cryotherapy on the Outcome of Pulpotomy and Root Canal Treatment

Start date: December 13, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to compare the outcome of total amputation and root canal treatment with or without cryotherapy in terms of postoperative pain, quality of life, and treatment success for the management of deep dentinal caries. The main questions it aims to answer are: Does cryotherapy influence the outcome, life quality and treatment success in total pulpotomy? Does cryotherapy influence the outcome, life quality and treatment success in root canal treatment? Does the outcome of total pulpotomy and root canal treatment differ in cases of pulpitis? There are 4 experimental groups: 1. Total pulpotomy with cryotherapy group 2. Total pulpotomy group (Control 1) 3. Root canal treatment with cryotherapy group 4. Root canal treatment group (Control 2)

NCT ID: NCT06181435 Recruiting - Dermatitis Atopic Clinical Trials

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 2)

Start date: December 21, 2023
Phase: Phase 3
Study type: Interventional

This is a parallel group, Phase 3, multinational, multicenter, randomized, double-blind, placebo-controlled, 3-arm monotherapy study for treatment of participants diagnosed with moderate to severe atopic dermatitis (AD), whose disease is not adequately controlled with topical prescription therapies or when those therapies are not advisable. The purpose of this study is to measure the efficacy and safety of treatment with amlitelimab solution for SC injection compared with placebo in participants with moderate to severe AD aged 12 years and older. Study details include: At the end of the treatment period, participants will have an option to enter a separate study: the blinded extension study EFC17600 (ESTUARY). For participants not entering the blinded extension Study EFC17600 (ESTUARY), the study duration will be up to 44 weeks including a 2 to 4-week screening, a 24-week randomized double-blind period, and a 16-week safety follow-up. For participants entering the blinded extension Study EFC17600 (ESTUARY), the study duration will be up to 28 weeks including a 2 to 4-week screening and a 24-week randomized double-blind period. The total treatment duration will be up to 24 weeks. The total number of visits will be up to 10 visits (or 9 visits for those entering the blinded extension study EFC17600 (ESTUARY).

NCT ID: NCT06180317 Recruiting - Endometrial Biopsy Clinical Trials

The Effect of Virtual Reality on Anxiety and Pain During Endometrial Biopsy

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The aim of this study was to reduce the anxiety and pain felt during endometrial biopsy procedure.

NCT ID: NCT06179095 Recruiting - Intrauterine Device Clinical Trials

The Effect of Virtual Reality on Anxiety During Intrauterine Device Insertion

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

This study was planned to determine whether the use of virtual reality glasses during intrauterine device insertion has an effect on the anxiety level of women.