There are about 15072 clinical studies being (or have been) conducted in Turkey. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
In this study, it was concluded that sclerostin and irisin may be alternative markers for evaluating the effectiveness of periodontal treatment and healing of periodontal tissues by affecting bone metabolism.
Rheumatoid Arthritis (RA) is a chronic, multisystemic, progressive autoimmune disease characterized by joint destruction in synovial tissue, causing joint swelling, pain and morning stiffness. It is estimated to affect 0.1%-2% of the world's adult population and more women than men. RA limits individuals' work, social, and home lives and functional capacities. Patients commonly experience pain and accompanying sleep problems. Interventions for these problems and symptom management are important. In this regard, this study was planned to examine the effect of distant reiki application on pain, functional status and sleep quality in rheumatoid arthritis patients.
''This study aims to determine the relationship between functional movement screen (FMS), core stabilization and Y balance test. The study will include evaluations on 30 handball players and 30 sedentary individuals.'' Functional movement analysis is a biomechanical screening and evaluation system to identify limitations and asymmetries in 7 basic movements. This system reveals the kinetic chain interaction between mobility and stability required for basic performance. Unlike conventional assessment methods, FHA focuses on the efficiency and quality of the movement pattern, not on the number of repetitions or weight lifted. The main aim of the study was to reveal the relationship between functional movement screen and core endurance and Y balance test evaluations in handball players with objective data. Functional movement is the general name of the activities performed by individuals for function and the movements performed by individuals for function are examined with analysis methods. In an effective analysis, if people do not have appropriate stability and mobility, it is determined from which muscle-muscle group or joint the problem originates. Analyses play a role in determining which of the stabilization, mobilization and flexibility factors are problematic at which stage of the function. In addition, these methods are effective in preventing possible injuries while helping to improve balance, strength and power characteristics of individuals. Core stabilization problems cause significant posture and stabilization problems. These problems are reflected in functional movements. Core stabilization problems are thought to have negative effects on functional movement analysis scores. Active athletes with this problem will be more affected. This study also aimed to observe the differences between athletes and sedentary individuals. Studies defined the core as the part of the body in the musculoskeletal system consisting of the proximal lower extremities, abdominal structures, hips, pelvis and spine and stated that the core muscles are composed of the trunk and pelvis muscles. It is argued that trunk and pelvis stabilization is essential for all movements of the extremities. The transversus abdominis and multifidus work in cocontraction and control excessive anterior pelvic tilt, which is known to be associated with femoral internal rotation and adduction. The musculature of the core is referred to as the muscular corset over the trunk and spine that stabilizes the body with or without limb movement. The strength and stabilization of the core affects the fitness and physical fitness of athletes. Core exercises should be included in exercise programs planned to improve athletic performance. Core endurance tests have been defined to reveal the relationship between core stabilization and performance. Lateral bridge test and trunk flexor test are the preferred core endurance tests in this study. The Y balance test is a dynamic test that requires strength, flexibility, core control and proprioception in a single-legged stance. Functional movement analysis, core stabilization tests and Y balance test are assessment scales that provide objective data on stabilization, postural alignment and spinal alignment. It is envisaged that these three assessment parameters will support each other after the study. Functional movements are widely used during both daily and sports activities. Core stabilization and dynamic balance are the factors that determine the quality of functional movements. These movements become more important for athletes as they affect their sporting success. Athletes need a good evaluation to ensure and maintain success. Since handball is defined as a sport that requires a lot of effort, the risks increase and it becomes clear that the evaluation should be done with a holistic approach.Injuries in handball develop due to multifactors.Biomechanical, kinesthetic and functional losses in players should be determined to prevent injuries.Functional movement analysis, core stabilization, Y balance test will give us detailed information about posture, limb alignment and asymmetry, spinal smoothness, dynamic balance and will give us the chance to analyze whether there is a correlation between these tests.
Adolescent Idiopathic Scoliosis is a three-dimensional deformity of the trunk and spine of unknown cause seen in adolescents. There are various conservative treatment methods to treat scoliosis. Manual therapy and exercises are a few of these treatments. There are studies showing that manual therapy reduces the severity of curvature, increases range of motion, modulates tissue/muscle extensibility, improves soft tissue movement limitation, relieves pain, and increases psychological well-being in scoliosis patients. In order to treat scoliosis, there are various exercise applications that are applied specifically to scoliosis, from physiotherapy applications. Core stabilization is one of the exercise methods that aim to keep the spine in the center. Virtual reality, on the other hand, is a three-dimensional simulation model that gives its participants the feeling of reality and allows mutual communication with a dynamic environment created by computers. Virtual reality is a method that provides the opportunity to work with task-based techniques by creating stimulating and entertaining environments, using people's interests and motivations. In a study, it was stated that two of the scoliosis-specific exercises were done through video-assisted games, but they stated that there was no difference because the number of exercises was low. Therefore, in this study, it was aimed to apply core stabilization exercises to scoliosis patients with virtual reality application and to investigate their effects on recovery in patients. In addition, it is planned to investigate whether the severity of the curvature in patients decreases further and whether it has an effect on other healing parameters by using the virtual reality treatment application together with manual treatment.
The goal of this clinical trial is to test the analgesic efficacy of rhomboid intercostal nerve block (RINB) in patients undergoing minimal invasive heart surgery (MIHS). The main questions it aims to answer are: - How will the total perioperative opioid consumption of the patients receiving RINB change? - How will RINB effect the patients' numeric rating scores for pain in the postoperative 24-hour period? - How will RINB effect the postoperative extubation times? - How will RINB effect the length of intensive care unit (ICU) stays on the postoperative period? - How will RINB effect the incidence of opioid related side effects? Participants will be divided in two groups: - Block group will receive a RINB before the surgery. - Control group will not receive any nerve block. Researchers will compare the results between the groups to see the postoperative effects concerning opioid consumption as well as the pain scores, respiratory parameters and ICU length of stay of the patients receiving RINB for minimal invasive heart surgery. The hypothesis of this study is that participants receiving RINB for MIHS will have a less total opioid consumption 24 hours postoperatively.
This study, was aimed to evaluate the effect of self-care support program (self-care training in endometriosis + motivational interview) applied to women with endometriosis on quality of life, self-care behaviors, depression, anxiety and stress levels.
Fibromyalgia syndrome (FMS) is a chronic disease characterized by widespread pain of unknown origin, fatigue, sleep disturbances, and cognitive problems. In the treatment of FMS, it is known that pharmacological therapy reduces fatigue as well as pain, increases functionality, and has positive effects on general well-being. In functional magnetic resonance imaging (fMRI) studies, suggestion following hypnotic induction has been reported to be better at pain control in patients with FMS. Self-hypnosis is a technique performed by the patient himself. The patients were randomly divided into two groups using the closed envelope technique as Group 1: Hypnosis and Group 2: Control. Patients who had communication problems, had other rheumatological diseases, had major medical disease and received treatment, had neurological and/or central nervous system disease, had been using antipsychotic medication, had been treated with psychotherapy for the last three months, and did not want to participate in the study were excluded from the study. Demographic characteristics of the participants and fibromyalgia effect beck depression and anxiety scale, Nottingham health profile and Visual Analogue Scale (VAS) were applied and the results were recorded. At the end of the 6th month, all scales and patient controls were made and re-evaluated. In this study, we aimed to evaluate the effects of controlled, standardized adjuvant hypnosis on pain, depression, anxiety, aerobic exercise practices, quality of life, and disease impact score in patients with FMS who had been under treatment for at least six months.
The aim of this project was to determine the effect of showing informative animations to children on anxiety and fear during inhalation therapy. This project is a randomized controlled trial. The population of the study will consist of children aged 7-12 years who apply to the Pediatric Emergency Department of Atatürk University Research Hospital between July 2022 and July 2023. The sample of the study will consist of children and their parents who present to the clinic on the dates determined, who are willing to participate in the study, and meet the inclusion criteria. Probability sampling will be used to select the sample. ''Introductory Information Form'', ''Child Fear Scale'', ''Facial Expression Rating Scale'' and ''Informative Animation'' will be used for data collection.
Background and objective: Tea is the second most consumed drink in the world after water. Gingivitis is among the most common infectious diseases. In this clinical study, Chlorhexidine Gluconate (CHX) was chosen as the positive control group and the clinical and biochemical efficacy of mouthwashes with green tea, white tea and essential oil (EO) as the active ingredients were aimed to be examined comprehensively. Methods: 112 participants with gingivitis were randomly assigned to 4 different groups that different mouthwashes were used for 4 weeks. CHX-MW group (0.12% CHX, as a positive control group), EO-MW group (Listerine), GT-MW group (5% Green tea), and WT-MW group (5% White tea). The effects of the mouthwashes on plaque, inflammation, and dental staining were evaluated by indexed scores at the beginning and the end of the 4th week. In addition, markers related to gingival inflammation (IL-1beta, MMP-8) and oxidative stress (TOS, TAS, OSI (TOS/TAS)) were evaluated on samples from the gingival crevicular fluid.
Although the scales used so far provide information about the neuromotor progression of a single baby, it is thought that they are not sufficient to distinguish babies from each other, and it is thought that there is no assessment battery that will adapt to the knowledge in their conditions and the functional development of babies. Therefore, the aim of our study is to reveal the applicability and psychometric properties of the Neonatal Infant Motor Assessment Scale (NIMAS) test, which reveals the neurological and motor performance of infants hospitalized in the NICU, both as automatic responses and functional behavior.