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NCT ID: NCT02383108 Completed - HIV Infection Clinical Trials

Strategy for Maintenance of HIV Suppression With Once Daily Integrate Inhibitor+Darunavir/Ritonavir in Children

SMILE
Start date: June 2016
Phase: Phase 2/Phase 3
Study type: Interventional

A two-arm, Phase 2/3 multicentre, open-label, randomised study evaluating safety and antiviral effect of current standard antiretroviral therapy compared to once daily integrase inhibitor administered with darunavir/ritonavir (DRV/r) in HIV-1 infected, virologically suppressed paediatric participants.

NCT ID: NCT02376907 Active, not recruiting - Jaundice Clinical Trials

Biliary Drainage in Patients With Duodenal Metal Stent

Start date: January 2010
Phase: N/A
Study type: Observational

This is a retrospective study to evaluate the outcomes of endoscopic biliary drainage according to the timing of distal malignant biliary obstruction (MBO) in relation to gastric outlet obstruction (GOO) and the location of GOO.

NCT ID: NCT02371252 Completed - Osteoporosis Clinical Trials

Efficacy and Safety of Brand Versus Generic Alendronate for Osteoporosis Treatment

Start date: April 2014
Phase: Phase 4
Study type: Interventional

Osteoporosis is a common disease defined as a decrease in bone mass and strength which increases risk of fragility fractures. This disorder may affecting health in many adults which causing disability, morbidity, and mortality. Current first-line medical therapy is bisphosphonates which alendronate is one of the most widely used. However, expenditure on medicines is one of the major problem of inadequate access to treatment. The investigators hypothesized that generic alendronate will have the same clinical efficacy as the brand formulation. Therefore, the result of this study is extremely crucial. If adequate efficacy of generic alendronate could be established and if it affords the same safety profile as those of brand alendronate, the use of generic alendronate could then be recommended.

NCT ID: NCT02371213 Completed - Premature Birth Clinical Trials

Social Networking on Mobile Phone to Improve Maternal and Neonatal Outcomes

HISONET
Start date: April 1, 2015
Phase: N/A
Study type: Interventional

The purpose of the study is to determine whether social networking on mobile phone in antenatal care health education is effective in the improvement of maternal and neonatal outcomes compared with usual antenatal care.

NCT ID: NCT02370134 Not yet recruiting - Parkinson's Disease Clinical Trials

Development of Parkinson's Glove for Detection and Suppression of Hand Tremor

Start date: February 2015
Phase: Phase 1
Study type: Interventional

This study is aimed to study the feasibility and safety of parkinson's glove that combined 2 module of tremor detection and tremor suppression with electrical muscle stimulation for using as device for rest tremor suppression in parkinson's disease patients

NCT ID: NCT02369887 Completed - PrEP Test and Treat Clinical Trials

Evaluation of a Facility-based Test, Treat, and Prevent HIV Program Among Men Who Have Sex With Men and Transgender Women in Thailand

PrEP
Start date: September 15, 2014
Phase:
Study type: Observational [Patient Registry]

This is a prospective observational cohort study that aims to enroll a total of 2000 Thai MSM and TG at five health facilities in four provinces of Thailand. Each participant will be followed for 18 months. Baseline and historical rates of HIV testing/re-testing, initial CD4 counts, retention in care, and ART adherence at the study clinics, at the study clinics combined, and national data (if available) will be compared with rates after implementation of the Test and Treat strategy. Analysis will also include an assessment of HIV prevalence and incidence. This study will use similar objectives, indicators, and procedures as those used in an ongoing Test and Treat study by the Thai Red Cross AIDS Research Centre in three tertiary care hospitals, and a study to be conducted with PEPFAR Key Populations Implementation Science (KPIS) funding through United States Agency for International Development (USAID), in community-based centers, allowing comparison of uptake and follow-up of MSM and TG using the Test and Treat strategy in a variety of settings.

NCT ID: NCT02367040 Active, not recruiting - Clinical trials for Lymphoma,Non-Hodgkin

Copanlisib and Rituximab in Relapsed Indolent B-cell Non-Hodgkin's Lymphoma (iNHL)

CHRONOS-3
Start date: August 3, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate whether copanlisib in combination with rituximab is superior to placebo in combination with rituximab in prolonging progression free survival (PFS) in patients with relapsed iNHL who have received one or more lines of treatment, including rituximab and who either had a treatment-free interval of ≥ 12 months after completion of the last rituximab-containing treatment, or who are unwilling to receive chemotherapy/for whom chemotherapy is contraindicated on reason of age, comorbidities, and/or residual toxicity.

NCT ID: NCT02364999 Completed - Clinical trials for Non-Small Cell Lung Cancer

A Comparative Study Of PF-06439535 Plus Paclitaxel-Carboplatin And Bevacizumab Plus Paclitaxel-Carboplatin Patients With Advanced Non-Squamous NSCLC

Start date: April 2015
Phase: Phase 3
Study type: Interventional

This is a multinational, double-blind, randomized, parallel-group Phase 3 clinical trial evaluating the efficacy and safety of bevacizumab-Pfizer plus paclitaxel and carboplatin versus bevacizumab-EU plus paclitaxel and carboplatin in first-line treatment for patients with advanced (unresectable, locally advanced, recurrent or metastatic) non-squamous NSCLC.

NCT ID: NCT02363660 Completed - HIV Clinical Trials

Gardasil Immunogenicity With Needle-Free Injection

GINI
Start date: January 2014
Phase: Phase 2
Study type: Interventional

1. Compare rates of seroconversion and GMTs generated following a 3-dose series of vaccine in women given low doses of vaccine by the ID route with the NFI (Group III) to those women given standard doses by the IM route with a needle and syringe (Group I) at 1 month, 6 months and 18 months following completion of the vaccination series. 2. Compare rates of seroconversion and GMTs generated following a 3-dose series of vaccine in women given standard doses of vaccine by the IM route with the NFI (Group II) to those women given standard doses by the IM route with a needle and syringe (Group I) at 1 month, 6 months and 18 months following completion of the vaccination series.

NCT ID: NCT02362581 Completed - Hemophilia A Clinical Trials

Comparison of Prophylaxis and On-demand Treatment in Children With Moderate to Severe Hemophilia A

Start date: December 2012
Phase: N/A
Study type: Interventional

Comparison of prophylaxis and on-demand treatment in children with moderate to severe hemophilia A. This study determines to compare the efficacy of prophylaxis and on-demand treatment in moderate to severe hemophilia A children in King Chulalongkorn Memorial Hospital, Bangkok, Thailand