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NCT ID: NCT00228475 Completed - Asthma Clinical Trials

A Study to Assess the Concentration of Budesonide in Breast Milk From Asthmatic Women

Start date: September 2004
Phase: Phase 4
Study type: Interventional

The purpose to measure the concentration of budesonide in breast milk of asthmatic mothers on their normal maintenance treatment with budesonide (Pulmicort Turbuhaler), and to estimate the exposure of budesonide to infants.

NCT ID: NCT00228150 Completed - Parkinson Disease Clinical Trials

Study of the Effect of SR57667B on the Progression of Symptoms in Patients With Parkinson's Disease

Start date: July 2003
Phase: Phase 2
Study type: Interventional

The primary objective is to assess the effect of SR57667B at the dose of 4 mg/d on the progression of Parkinson symptoms in patients with early PD. The primary outcome will be the time to progression of disability warranting initiation of L-dopa or a dopamine agonist. Secondary outcomes will comprise assessments of symptoms, activities of daily living and global clinical status.

NCT ID: NCT00226499 Completed - Varicella Clinical Trials

Evaluate Vaccine Against Chickenpox and a Combined Vaccine Against 4 Viral Childhood Diseases: Measles, Mumps, Rubella and Chickenpox

Start date: September 1, 2005
Phase: Phase 3
Study type: Interventional

An observer-blind study to evaluate GlaxoSmithKline Biologicals' live attenuated varicella vaccine and GlaxoSmithKline Biologicals' combined measles-mumps-rubella-varicella vaccine in the prevention of varicella disease in children. The Protocol Posting has been updated in order to comply with the FDA Amendment Act, Sep 2007.

NCT ID: NCT00225823 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Study In Adults And Adolescents With Seasonal Allergic Rhinitis.

Start date: May 2005
Phase: Phase 3
Study type: Interventional

Compare the efficacy and safety of an investigational nasal spray compared with placebo nasal spray in the treatment of seasonal allergic rhinitis. Allergic rhinitis is an inflammatory disorder of the upper airway that occurs following allergen exposure. The focus of this study, seasonal allergic rhinitis (SAR), is one type of allergic rhinitis that is triggered by the pollen from trees, grasses, and weeds. Commonly referred to as 'hay fever', it is characterized by sneezing, nasal congestion and pruritus, rhinorrhea, and pruritic, watery, red eyes.

NCT ID: NCT00224484 Completed - Herpes Simplex Clinical Trials

Safety Study of Herpes Simplex Vaccine in HSV Seronegative and Seropositive Females Between 10 and 17 Years Old

Start date: April 7, 2004
Phase: Phase 3
Study type: Interventional

Main goal of this study is to compare the occurrence of serious adverse events (SAEs) between the herpes simplex (gD2-AS04) vaccine group and the Saline control group throughout the study period (up to month 12). The Protocol Posting has been updated in order to comply with the FDA Amendment Act, Sep 2007.

NCT ID: NCT00221845 Completed - Hypertension Clinical Trials

Effect of Strict Blood Pressure Control and ACE-Inhibition on Progression of Chronic Renal Failure in Pediatric Patients

ESCAPE
Start date: January 1998
Phase: Phase 3
Study type: Interventional

In children with chronic kidney disease, progression to end-stage renal failure is associated with high patient morbidity and poor quality of life. In adults, inhibition of the renin angiotensin system (RAS) slows down the rate of renal failure progression. This concept is as yet unproven in children, in whom chronic renal failure (CRF) is more commonly due to hypo/dysplastic malformations than to acquired glomerulopathies as typical for adult chronic kidney disease. The current project aims at assessing the genetic and molecular mechanisms and cardiovascular consequences of progressive CRF and to develop a strategy of pharmacological renoprotection in children.

NCT ID: NCT00221377 Completed - Clinical trials for Presence of Post-extubation Laryngeal Oedema

"Cuffed Versus Uncuffed Tracheal Tubes in Small Children"

Start date: April 2005
Phase: N/A
Study type: Interventional

This randomized controlled multi-centre trial in children from birth up to < 5 years of age aims to demonstrate equivalence as to the major outcome of post-extubation airway injury (stridor) comparing uncuffed tracheal tubes to current tracheal tubes with modern high volume - low pressure cuff combined with a cuff pressure release valve.

NCT ID: NCT00220779 Completed - Clinical trials for Multiple Sclerosis, Relapsing-Remitting

Immune Globulin Intravenous (IGIV) To Treat Relapsing, Remitting Multiple Sclerosis

PRIVIG
Start date: December 2002
Phase: Phase 2
Study type: Interventional

The trial will study 2 doses of Immune Globulin Intravenous (Human), 10% Caprylate/Chromatography Purified (IGIV-C) for the number of relapses that occur in a 1 year treatment period.

NCT ID: NCT00219609 Completed - Ejaculation Clinical Trials

Assessment Of Safety Of UK-390,957

Start date: January 2005
Phase: Phase 2/Phase 3
Study type: Interventional

To determine whether UK-390,957 is a safe treatment for premature ejaculation.

NCT ID: NCT00219583 Completed - Ejaculation Clinical Trials

Assessment Of Efficacy and Safety Of UK-390,957 In Men With Premature Ejaculation

Start date: August 2004
Phase: Phase 2/Phase 3
Study type: Interventional

Assessment of efficacy and safety UK-390,957.