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NCT ID: NCT00306215 Completed - Crohn's Disease Clinical Trials

A Study to Evaluate the Efficacy and Safety of CCX282-B in Subjects With Moderate to Severe Crohn's Disease

Start date: March 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether CCX282-B is effective in treating patients with moderate to severe Crohn's Disease.

NCT ID: NCT00306150 Terminated - Clinical trials for Blood Loss, Surgical

Efficacy and Safety of Aprotinin on Transfusion Requirements in Patients Undergoing Radical or Total Cystectomy

Start date: December 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess if aprotinin (BAYA0128), given intravenously during your surgery, is safe and can help reduce the need for a blood transfusion during bladder surgery.

NCT ID: NCT00304252 Terminated - Crohn's Disease Clinical Trials

Safety and Efficacy of Treatment With Interferon Beta-1a Rebif® in Patients With Crohn's Disease

Start date: November 2001
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of interferon beta-1a in maintaining remission in patients with Crohn's disease.

NCT ID: NCT00303459 Completed - Clinical trials for Pulmonary Arterial Hypertension

Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)

Compass-2
Start date: May 2006
Phase: Phase 4
Study type: Interventional

COMPASS-2 is a Phase 4, prospective, randomized, double-blind, placebo-controlled, event-driven study evaluating the effect of bosentan on the time to first confirmed morbidity/mortality event in patients with symptomatic PAH already receiving sildenafil therapy. Patients must have been receiving doses of sildenafil equal to or greater than 20 mg t.i.d. for at least 12 weeks prior to being randomized. The study continued until the predefined target number of morbidity/mortality events was reached.

NCT ID: NCT00303381 Completed - Ulcerative Colitis Clinical Trials

Safety and Efficacy of Interferon-Beta-1a (Rebif®) for Treating Subjects With Acute Symptoms of Ulcerative Colitis

Start date: December 2001
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of interferon-beta-1a in subjects with active ulcerative colitis (UC).

NCT ID: NCT00302016 No longer available - Clinical trials for Chronic Myeloid Leukemia

Expanded Access Program of AMN107 in Imatinib-resistant or Intolerant Adult Patients With Chronic Myeloid Leukemia

Start date: January 2006
Phase: Phase 3
Study type: Expanded Access

This study will further evaluate if AMN107 is safe in adults with chronic myeloid leukemia who are resistant or intolerant to imatinib and to provide patients access to this new drug until the drug becomes commercially available.

NCT ID: NCT00300885 Terminated - Clinical trials for Carcinoma, Non-Small Cell Lung

A Randomized Controlled Trial Comparing Safety and Efficacy of Carboplatin and Paclitaxel Plus or Minus Sorafenib (BAY 43-9006) in Chemonaive Patients With Stage IIIB-IV Non-Small Cell Lung Cancer (NSCLC)

Start date: February 2006
Phase: Phase 3
Study type: Interventional

A randomized controlled trial comparing safety and efficacy of carboplatin and paclitaxel plus or minus sorafenib in chemonaive patients with stage III-IV non-small cell lung cancer.

NCT ID: NCT00300846 Completed - Schizophrenia Clinical Trials

A Study of Adjunctive Treatment of Aripiprazole in Schizophrenic Patients

Start date: December 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the effect on patient weight of adjunctive therapy of aripiprazole with clozapine versus clozapine monotherapy, in schizophrenic patients who are not optimally controlled on clozapine.

NCT ID: NCT00300729 Active, not recruiting - Clinical trials for Non-Small Cell Lung Cancer

Effect of Celecoxib on Survival in Patients With Advanced Non-Small Cell Lung Cancer Receiving Chemotherapy

CYCLUS
Start date: May 2006
Phase: Phase 3
Study type: Interventional

The primary purpose of the study is to investigate if daily treatment with celecoxib, an inhibitor of cyclooxygenase-2, can prolong survival in patients with advanced non-small cell lung cancer who receive anticancer chemotherapy as their primary treatment. Secondary endpoints of the study are: health-related quality of life, toxicity, cardiovascular events, progression-free survival, and biological markers (VEGF, proteomics).

NCT ID: NCT00300339 Completed - Clinical trials for Intermittent Claudication

Mixed Antagonist of Serotonin for Claudication Optimal Therapy

MASCOT
Start date: February 2006
Phase: Phase 2
Study type: Interventional

To investigate in patients suffering from intermittent claudication due to Fontaine stage II PAD whether a 24-week treatment by SL650472 OD on top of clopidogrel may result in an improvement of walking capacity, by comparing three doses of SL650472 to placebo, and to calibrate such effect versus cilostazol