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NCT ID: NCT00667823 Completed - Clinical trials for Pulmonary Arterial Hypertension

Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension

SERAPHIN OL
Start date: October 17, 2008
Phase: Phase 3
Study type: Interventional

The main objective of the AC 055 303/SERAPHIN OL study, which will follow the AC 055 302/SERAPHIN study, will be to assess the long-term safety and tolerability of ACT 064992 in patients with symptomatic PAH.

NCT ID: NCT00667810 Terminated - Alzheimer Disease Clinical Trials

Study Evaluating The Efficacy And Safety Of Bapineuzumab In Alzheimer Disease Patients

Start date: June 2008
Phase: Phase 3
Study type: Interventional

This is a study to evaluate the efficacy and safety of multiple doses of bapineuzumab in patients with mild to moderate Alzheimer Disease. Patients will receive either bapineuzumab or placebo. Each patient's participation will last approximately 1.5 years.

NCT ID: NCT00666458 Completed - Type 2 Diabetes Clinical Trials

18-week add-on to Metformin Comparison of Saxagliptin and Sitagliptin in Adult Patients With Type 2 Diabetes (T2D)

Start date: April 2008
Phase: Phase 3
Study type: Interventional

Saxagliptin is a new investigational medication being developed for treatment of type 2 diabetes. This study is designed to assess the efficacy and tolerability of saxagliptin in addition to metformin and compare to sitagliptin in addition with metformin.

NCT ID: NCT00665496 Completed - Clinical trials for Erectile Dysfunction

A Study to Investigate the Time to Onset of Action of 10 mg and 20 mg of Vardenafil Compared to Placebo in Males With Erectile Dysfunction

Start date: June 2003
Phase: Phase 3
Study type: Interventional

This purpose of the study was to evaluate the earliest time to onset of action in adults with erectile dysfunction (often called impotence). In this study vardenafil has been compared to placebo. Patients were asked to fill in questionnaires and a diary in which they filled in details about attempts at sexual activity during study period. Patients received also a stopwatch to record the time of onset of erection. Stopwatch should be started immediately prior to initiating sexual activity and stopped when an erection perceived to be adequate for penetration was obtained.

NCT ID: NCT00665275 Completed - Rheumatic Diseases Clinical Trials

Complementary and Alternative Medicine Among Outpatients With Inflammatory Rheumatic Diseases in Western Sweden

Start date: March 2007
Phase: N/A
Study type: Observational

This is an observational study aiming to study the use of complementary and alternative medicine (CAM) drugs and methods among patients with inflammatory rheumatic diseases, at Rheumatology clinics in western Sweden and also to investigate possible associations between CAM using habits and other characteristics of the patients.

NCT ID: NCT00664521 Completed - Clinical trials for Rheumatoid Arthritis

Atacicept in Combination With Rituximab in Subjects With Rheumatoid Arthritis

August III
Start date: March 2008
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to assess the safety and tolerability of combined treatment with atacicept and rituximab in subjects with active rheumatoid arthritis receiving re-treatment with rituximab.

NCT ID: NCT00662831 Completed - Diabetic Foot Ulcer Clinical Trials

Study Of The Effect Of Fragmin In The Treatment Of Neuroischaemic Foot Ulcers In Diabetic Patients

FEENICS
Start date: April 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of the study isto see the effect of Fragmin on the healing of diabetic foot ulcers by determining the number of subjects with ≥50% reduction in ulcer surface area including intact skin healing.

NCT ID: NCT00662740 Terminated - Clinical trials for Pulmonary Disease, Chronic Obstructive

Tiotropium/Salmeterol Inhalation Powder (Spiriva Handihaler and Salmeterol Polyethylene (PE) Capsule) in Chronic Obstructive Pulmonary Disease (COPD)

Start date: April 15, 2008
Phase: Phase 3
Study type: Interventional

The primary objectives of this study are to assess bronchodilator efficacy as determined by forced expiratory volume in one second (FEV1), the effect on dyspnoea as determined by the Baseline Dyspnoea Index/Transition Dyspnoea Index (BDI/TDI), the effect on health status as determined by the St George Respiratory Questionnaire (SGRQ) and the effect on chronic obstructive pulmonary disease (COPD) exacerbations.

NCT ID: NCT00662649 Completed - Multiple Sclerosis Clinical Trials

Long-term Efficacy and Safety of Fingolimod (FTY720) in Patients With Relapsing-remitting Multiple Sclerosis

Start date: February 2008
Phase: Phase 3
Study type: Interventional

This extension study of was designed to evaluate the long-term safety, tolerability, and efficacy of fingolimod (FTY720) in patients with multiple sclerosis. The Extension study was an extension to the 24-month Core study (CFTY720D2301/NCT00289978).

NCT ID: NCT00662597 Terminated - Clinical trials for Non-Small Cell Lung Cancer

ASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung Cancer

ATRACT-1
Start date: April 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if adding ASA404 to standard chemotherapy makes the cancer treatment more effective in patients with advanced lung cancer.