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NCT ID: NCT00157248 Terminated - Stroke Clinical Trials

Long-term, Open-label Follow-up Treatment of Patients With A-fib Who Have Been Previously Treated With BIBR 1048

Start date: December 2003
Phase: Phase 2
Study type: Interventional

To determine the long term safety and efficacy of BIBR 1048 in patients with chronic atrial fibrilla tion, with or without concomitant chronic treatment with acetylsalicylic acid (ASA).

NCT ID: NCT00154427 Terminated - Clinical trials for Acquired Bleeding Disorder

Use of Activated Recombinant Human Factor VII in Cardiac Surgery

Start date: August 2004
Phase: Phase 2
Study type: Interventional

This trial is conducted in Africa, Asia, Europe, South America and the United States of America (USA). The trial is planned to investigate the safety and efficacy of NovoSeven® in the management of post-operative bleeding in patients following cardiac surgery.

NCT ID: NCT00151788 Terminated - Atherosclerosis Clinical Trials

Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Disease. This Study is Also Known as CAPTIVATE.

Start date: February 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The effects of pactimibe versus placebo on the progression of atherosclerosis in the carotid arteries will be assessed using standard ultrasound techniques.

NCT ID: NCT00151736 Terminated - Clinical trials for Chronic Lymphocytic Leukemia

Safety and Efficacy of SDX-101 (R-Etodolac) in Combination With Chlorambucil, and That of Chlorambucil Alone, in Patients With Chronic Lymphocytic Leukemia (CLL)

Start date: September 2004
Phase: Phase 2
Study type: Interventional

This is a Phase 2, multi-center, open label, randomized clinical study to evaluate the safety and efficiency of SDX-101 in combination with chlorambucil (CLB) and chlorambucil alone in Chronic Lymphocytic Leukaemia (CLL) patients. The study treatment period will be approximately 24-26 weeks with a follow-up period of approximately 8 weeks. Following the end of treatment, patients with a confirmed complete response, partial response or stable disease will be followed for up to 2 years to assess time to disease progression. Approximately 80 patients with documented diagnosis of B-cell CLL by standard clinical and immunophenotyping criteria will be enrolled into the SDX-101-03 study. This study is being conducted in the following European countries: France, Germany, Poland, Sweden and the United Kingdom.

NCT ID: NCT00137345 Terminated - Kidney Transplant Clinical Trials

Study Comparing Sirolimus With Cyclosporine in a Calcineurin Inhibitor (CNI)-Free Regimen in Kidney Transplant Recipients

Start date: June 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if one drug is superior to another with regard to safety and the preservation of renal function after a kidney transplant.

NCT ID: NCT00134264 Terminated - Diabetes Mellitus Clinical Trials

A Study Examining Torcetrapib/Atorvastatin And Atorvastatin Effects On Clinical CV Events In Patients With Heart Disease

ILLUMINATE
Start date: July 2004
Phase: Phase 3
Study type: Interventional

The Torcetrapib project was terminated on December 2, 2006 due to safety findings. To demonstrate if torcetrapib/atorvastatin can reduce the risk for major cardiovascular disease events, when compared to atorvastatin alone, in patients with coronary heart disease or risk equivalents

NCT ID: NCT00133224 Terminated - Prostate Cancer Clinical Trials

Docetaxel in Combination With GVAX ® Immunotherapy Versus Docetaxel and Prednisone in Prostate Cancer Patients

Start date: July 2005
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to compare the duration of survival between patients receiving docetaxel in combination with the GVAX® vaccine for prostate cancer versus patients receiving docetaxel and prednisone treatment in patients with prostate cancer who no longer respond to hormone therapy, who have documented metastases with pain. Patients may have had up to one prior non-taxane chemotherapy treatment.

NCT ID: NCT00128115 Terminated - Hip Fracture Clinical Trials

Treatment of Sarcopenia in Post-Hip Fracture Patients (0677-032)

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to demonstrate an improvement in physical functional recovery, following administration of Drug for 24 weeks, in patients who have recently experienced a hip fracture. This study will also evaluate the safety and tolerability of Drug. This is an early phase trial and some specific protocol information is proprietary and not publicly available at this time. (Full information is available to trial participants).

NCT ID: NCT00124891 Terminated - Arrhythmias Clinical Trials

Study Evaluating GAP-486 in Non-sustained Ventricular Tachycardia

Start date: June 1, 2005
Phase: Phase 2
Study type: Interventional

To determine whether the administration of test article will decrease the occurrence of ventricular arrhythmias in patients who have acute coronary syndrome (unstable angina, ST segment elevated myocardial infarction or myocardial infarction without ST elevation).

NCT ID: NCT00089856 Terminated - Prostate Cancer Clinical Trials

GVAX® Vaccine for Prostate Cancer vs Docetaxel & Prednisone in Patients With Metastatic Hormone-Refractory Prostate Cancer

Start date: July 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the duration of survival between GVAX® immunotherapy for prostate cancer and chemotherapy treatment in patients with prostate cancer who no longer respond to hormone therapy, who have documented metastases, and who have not been treated with chemotherapy in the past.