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NCT ID: NCT00354094 Terminated - Pain Clinical Trials

[S,S]-Reboxetine Long Term Safety Study In Post-Shingles Pain.

Start date: November 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the long term (up to 2 years) safety and tolerability of [S,S]-Reboxetine in patients with pain after shingles.

NCT ID: NCT00353574 Terminated - Hypertension Clinical Trials

DORADO-EX: Long-Term Safety Extension Study to the Phase 3 DORADO Study (Protocol DAR-311) of Darusentan in Resistant Hypertension

Darusentan
Start date: September 2006
Phase: Phase 3
Study type: Interventional

This is a research study of a new experimental drug called darusentan. Darusentan is not currently approved by the United States (U.S.) Food and Drug Administration (FDA) for use in the U.S., which means that a doctor cannot prescribe this drug. The purpose of this study is to evaluate the long-term safety of darusentan in subjects with resistant systolic hypertension despite treatment with full doses of three or more antihypertensive medications, including a diuretic.

NCT ID: NCT00348894 Terminated - Pain Clinical Trials

[S,S]-Reboxetine Long Term Safety Study In Chronic Painful Diabetic Peripheral Neuropathy.

Start date: July 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the long-term safety and tolerability of [S,S]-Reboxetine in patients with chronic painful diabetic peripheral neuropathy

NCT ID: NCT00334685 Terminated - Pain Clinical Trials

[S,S]-Reboxetine Add-On Trial

Start date: August 22, 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the effectiveness of adjunctive treatment of pregabalin with [S,S]-Reboxetine against pregabalin monotherapy in patients with PHN

NCT ID: NCT00334646 Terminated - Clinical trials for Nausea and Vomiting, Chemotherapy-Induced

Cyclophosphamide Drug Interaction Study In Cancer Patients

Start date: August 10, 2005
Phase: Phase 1
Study type: Interventional

This study is designed to evaluate the potential pharmacokinetic interaction between oral GW679769 and IV (intravenous) cyclophosphamide when administered to cancer patients.

NCT ID: NCT00322218 Terminated - Clinical trials for Lymphoma, Large Cell, Diffuse

Study Comparing Zevalin Regimen With no Further Treatment in Patients With Diffuse Large B-cell Lymphoma.

Start date: May 2006
Phase: Phase 3
Study type: Interventional

This study treats patients with diffuse large B-cell lymphoma whose disease is in complete remission due to previous treatment with Cyclophosphamide Doxorubicin hydrochloride Vincristine Prednisolone- Rituximab (CHOP-R). Half of the patients received Zevalin and the other half receive no further anti-cancer treatment. The two patient groups compared to determine if Zevalin given after CHOP-R therapy provides greater benefits than receiving no additional anti-cancer therapy after CHOP-R.

NCT ID: NCT00322036 Terminated - Alzheimer Disease Clinical Trials

Global Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's

Start date: May 2006
Phase: Phase 3
Study type: Interventional

This is a multinational, randomized, double blind, placebo controlled, parallel group study comparing the safety and efficacy of daily dosing of 800 mg twice daily MPC-7869 to placebo. Study subjects will have the diagnosis of mild dementia of the Alzheimer's type. Subjects may be taking approved medication for Alzheimer's disease provided the dose has been stable for at least 6 months.

NCT ID: NCT00320190 Terminated - Clinical trials for Leukemia, Myeloid, Chronic

Study of Dasatinib in Patients With Chronic Phase Chronic Myeloid Leukemia and a Suboptimal Response to Imatinib

Start date: August 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the efficacy of dasatinib with that of high-dose (800-mg) imatinib in participants with chronic phase chronic myeloid leukemia who achieved only a suboptimal response after at least 3 months of monotherapy with 400-mg imatinib. The safety of these treatments will also be evaluated.

NCT ID: NCT00317265 Terminated - Clinical trials for Coronary Artery Disease

Coronary Bypass Surgery Trial: Complete Arterial Revascularization and Conventional Coronary Artery Surgery

Start date: January 1999
Phase: N/A
Study type: Interventional

This is a randomized, prospective European Multicenter Study comparing complete arterial revascularization of the coronary arteries using arterial graft material exclusively and “conventional” coronary artery bypass surgery using the left internal thoracic artery as graft to the left anterior descending artery (LAD) and vein grafts to other vessels to be bypassed.

NCT ID: NCT00308464 Terminated - Clinical trials for Growth Hormone Deficiency

A Study To Evaluate The Dose Response And Safety Of PHA-794428 In Adults With Growth Hormone Deficiency

Start date: July 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to explore the safety, toleration and dose response of PHA-794428 after multiple weekly injections in male and female growth hormone deficient patients.