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NCT ID: NCT00399009 Terminated - Rectal Cancer Clinical Trials

Comparative Study of Circular Stapling Instruments

Start date: January 2004
Phase: N/A
Study type: Interventional

After removing the rectum at surgery, bowel continuity can sometimes be restored by an anastomosis between the anus and the bowel. This anastomosis is most commonly created by the use of surgical circular stapling instruments. In a retrospective pilot study the risk of developing an acute leak in the anastomosis was increased with one of the most commonly used instruments in Sweden as compared to the other brand in use. In the current study the patient is randomized to either one of the instruments after a resection of the rectum for rectal cancer.

NCT ID: NCT00396448 Terminated - Obesity Clinical Trials

Effect of 2-year Administration of CP-945,598 on Weight Loss Efficacy and Safety.

Start date: February 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to examine the long-term weight loss and safety of CP-945,598 in obese adults

NCT ID: NCT00391196 Terminated - Obesity Clinical Trials

A 1-Year Study On The Effects Of CP-945,598 For The Treatment Of Obesity In Overweight Type 2 Diabetic Patients

Start date: November 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if CP-945,598 is effective in the treatment of obesity in type 2 diabetic patients.

NCT ID: NCT00387686 Terminated - Fractures Clinical Trials

A Phase 2/3 Multicenter, Controlled Trial Of rhBMP-2/CPM In Tibial Fractures

Start date: November 2006
Phase: Phase 2/Phase 3
Study type: Interventional

The primary objective of this study is to assess whether a single dose of rhBMP-2/CPM administered at the fracture site via percutaneous injection, in combination with standard of care, accelerates fracture union and return to normal function in subjects who have a closed diaphyseal tibial fracture when compared to standard of care alone.

NCT ID: NCT00381095 Terminated - Cancer Clinical Trials

A Study To Evaluate Pregabalin In The Treatment Of Moderate To Severe Chronic Bone Pain Related To Metastatic Cancer

COPE
Start date: December 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the analgesic efficacy of flexibly-dosed pregabalin in the adjunctive treatment of subjects with cancer-induced bone pain.

NCT ID: NCT00372996 Terminated - Breast Neoplasms Clinical Trials

Study Of CP-751,871 In Combination With Exemestane In Postmenopausal Women With Hormone Receptor Positive Advanced Breast Cancer

Start date: February 2007
Phase: Phase 2
Study type: Interventional

To test the efficacy of CP-751,871 combined with exemestane in the treatment of postmenopausal patients with hormone positive advanced breast cancer

NCT ID: NCT00364533 Terminated - Arthroplasty Clinical Trials

A Study to Evaluate the Effectiveness and Safety of Tapentadol(CG5503) in the Treatment of Acute Pain After Hip Replacement Surgery Compared With Oxycodone and Placebo Followed by a Voluntary Open-Label Extension For Safety

Start date: October 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to test in patients who have had hip replacement surgery the effectiveness (level of pain control) and the safety of 3 different dose levels of CG5503 compared with placebo and with 10-mg oxycodone during the 72-hour double-blind period and to assess the safety of the drug for 9 days after patients completed the double blind period.

NCT ID: NCT00359632 Terminated - Clinical trials for Optic Nerve Diseases

Study to Evaluate Eye Function in Patients Taking Linezolid for Six Weeks or Greater

Start date: November 2008
Phase: Phase 3
Study type: Interventional

To understand and characterize the effects of linezolid on the optic nerve by observing and following patients who have been treated with linezolid for six weeks or longer for the development of signs or symptoms of visual disturbance or eye disorders.

NCT ID: NCT00358566 Terminated - Clinical trials for Advanced Unresectable Pancreatic Cancer

GV1001 and Gemcitabine in Sequential Combination to Gemcitabine Monotherapy in Pancreatic Cancer

Start date: June 2006
Phase: Phase 3
Study type: Interventional

To investigate the efficacy of GV1001 in sequential combination with gemcitabine in locally advanced and metastatic adenocarcinoma of the pancreas.

NCT ID: NCT00356421 Terminated - Clinical trials for Diabetes Mellitus, Type 1

A Clinical Trial Comparing Efficacy and Safety of Exubera® and Humalog®

Start date: November 2006
Phase: Phase 4
Study type: Interventional

To compare efficacy and safety of Exubera® vs Humalog in patients with type 1 diabetes mellitus