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NCT ID: NCT00319033 Completed - Clinical trials for Interstitial Lung Disease

Open-label Study With Bosentan in Interstitial Lung Disease

BUILD 2 OL
Start date: July 2004
Phase: Phase 2/Phase 3
Study type: Interventional

This study will asses the long term safety and efficacy of oral bosentan to patients suffering from Interstitial Lung Disease.

NCT ID: NCT00318461 Completed - Clinical trials for Diabetes Mellitus, Type 2

To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together

LEAD-2
Start date: May 2006
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe, Oceania, Africa, Asia and South America. This trial is designed to show the effect of treatment with liraglutide when adding to existing metformin therapy and to compare it with the effects of metformin monotherapy and combination therapy of metformin and glimepiride. Two trial periods: A 6 month (26 weeks) randomised, double-blinded period followed by an 18 months open-label extension, in total 2 years (104 weeks).

NCT ID: NCT00316095 Completed - Hypertension Clinical Trials

Combination of Telmisartan and Simvastatin in the Treatment of Hypertension and Hypercholesterolemia

Start date: April 2006
Phase: Phase 3
Study type: Interventional

This study will investigate two registered drugs, one for the treatment of high blood pressure and one for the treatment of elevated cholesterol. High blood pressure (hypertension) is a common medical condition affecting millions of people worldwide. A wide variety of effective drug treatments is available to reduce blood pressure. Elevated cholesterol (hypercholesterolemia) is a common medical condition affecting people worldwide. A wide variety of effective drug treatments is available to reduce cholesterol levels. Hypertension and hypercholesterolemia often occur together. They are both important risk factors for the development of heart and vessel diseases (e.g. heart attack or stroke). Current guidelines advise treatment of high blood pressure and elevated cholesterol to reduce the risk of cardiovascular diseases. This study will test the simultaneous use of a drug to reduce blood pressure and a drug to reduce elevated cholesterol. Both drugs are registered and are effective. The drug for treatment of high blood pressure is telmisartan Micardis). The drug for treatment of elevated cholesterol is simvastatin (Zocor). Since hypertension and hypercholesterolemia frequently occur together, the purpose of this study is to investigate whether both drugs can be used simultaneously. A low dose and a high dose of these drugs will be used. It will be investigated whether each of the drugs is still as effective when given together, at the same time of day, with the other drug.

NCT ID: NCT00314860 Completed - Clinical trials for Restless Legs Syndrome

RLS In Adults: Comparing Immediate Release Formulation With Extended Release Formulation Of Ropinirole

Start date: February 2006
Phase: Phase 3
Study type: Interventional

Restless Legs Syndrome (RLS) study in adults comparing immediate release ropinirole with extended release ropinirole over 12 weeks

NCT ID: NCT00313300 Completed - Clinical trials for Acute Coronary Syndrome (ACS)

Safety Study of Apixaban in Recent Acute Coronary Syndrome

Start date: May 2006
Phase: Phase 2
Study type: Interventional

The purpose of this clinical research study is to determine whether apixaban will be safe in people who have recently had unstable angina or a heart attack.

NCT ID: NCT00312845 Completed - Clinical trials for Non-Hodgkin's Lymphoma

Study of VELCADE and Rituximab in Patients With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if the combination of VELCADE and rituximab improves progression free survival relative to rituximab alone in patients with relapsed or refractory B-cell non-Hodgkin's lymphoma (B-NHL) who never received rituximab or who have previously responded to rituximab. This is an international study being conducted in the United States and in many countries around the world. A complete list of study locations is listed below.

NCT ID: NCT00312156 Completed - Diabetes Clinical Trials

Comparison of Efficacy and Safety of Insulin Detemir and NPH Insulin in Children and Adolescents With Type 1 Diabetes

Start date: August 2002
Phase: Phase 3
Study type: Interventional

The trial is conducted in Europe and Middle East. The aim of the trial is to compare the use of Insulin Detemir once or twice daily combined with mealtime Insulin Aspart against that of NPH Insulin once or twice daily combined with mealtime Insulin Aspart. The trial involves children and adolescents with Type 1 Diabetes.

NCT ID: NCT00311194 Completed - Heart Failure Clinical Trials

Trial of an Interactive CD-Program on 6 Months Readmission Rate in Patients With Heart Failure

Start date: February 1998
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether extra education of patients with chronic heart failure can reduce 6 months readmission rate to hospital.

NCT ID: NCT00310934 Completed - Heroin Dependence Clinical Trials

A Stepwise Strategy Utilizing Buprenorphine and Methadone

Start date: August 2005
Phase: Phase 4
Study type: Interventional

The objective of this study is to compare optimally given methadone maintenance treatment (MMT) for heroin dependence with a novel, sequential strategy, where patients are offered buprenorphine as first line treatment, allowed dose adjustments as needed, and switched to methadone if the maximal dose of buprenorphine is insufficient.

NCT ID: NCT00309738 Completed - Clinical trials for Hypercholesterolemia

Study to Compare the Efficacy and Safety of Pitavastatin and Simvastatin

Start date: September 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of pitavastatin with that of simvastatin in patients with risk factors for heart disease.