Clinical Trials Logo

Filter by:
NCT ID: NCT00411736 Completed - Cystic Fibrosis Clinical Trials

Scandinavian Cystic Fibrosis Azithromycin Study

Start date: May 2008
Phase: Phase 4
Study type: Interventional

In patients with Cystic Fibrosis, recurrent airway infection caused by Pseudomonas aeruginosa ultimately leads to chronic airway infection. The purpose of this study is to determine whether supplementary low-dose azithromycin to standard inhaled colistin and oral ciprofloxacin in the treatment of intermittent pseudomonas airway-infection can postpone the next episode of intermittent pseudomonas airway-infection and prevent development of chronic airway-infection.

NCT ID: NCT00411645 Completed - Clinical trials for Cytomegalovirus Infections

Prophylactic Use of Maribavir for the Prevention of Cytomegalovirus (CMV) Disease in Stem Cell Transplant Recipients

Start date: December 13, 2006
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to investigate whether or not maribavir is safe and effective for preventing CMV disease when taken by mouth for up to 12 weeks in patients who have had a stem cell transplant.

NCT ID: NCT00411580 Completed - Alzheimer's Disease Clinical Trials

Safety and Tolerability Study in Patients With Mild to Moderate Alzheimer's Disease (AD)

Start date: June 2005
Phase: Phase 1
Study type: Interventional

This study will evaluate the safety and tolerability and Aß-specific antibody response of CAD106 in patients with mild to moderate Alzheimer's Disease. Patients also had a 2 year follow-up to assess disease progression where no drug was administered.

NCT ID: NCT00411385 Completed - Chronic Hepatitis C Clinical Trials

Efficacy of Albumin Interferon Alfa-2b With Ribavirin Compared to Peg-IFN Alfa-2a With Ribavirin in IFN Naive Patients Geno2/3

Start date: February 2007
Phase: Phase 3
Study type: Interventional

This is a phase 3, randomized, multi-center study to evaluate the efficacy and safety of albumin interferon alfa-2b (alb-IFN)in combination with ribavirin compared with peginterferon alfa-2a (PEGASYS or PEG-IFNa2a) in combination with ribavirin in subjects with chronic hepatitis C, genotype 2/3 who are IFNa treatment naive.

NCT ID: NCT00410384 Completed - Clinical trials for Systemic Lupus Erythematosus

A Study of Belimumab in Subjects With Systemic Lupus Erythematosus

BLISS-76
Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety, tolerability, and impact on quality of life of two different doses of belimumab administered in addition to standard therapy in subjects with active, autoantibody-positive systemic lupus erythematosus (SLE) disease.

NCT ID: NCT00410046 Completed - Clinical trials for Ankylosing Spondylitis

Extension Study Evaluating Etanercept in Ankylosing Spondylitis

Start date: December 2006
Phase: Phase 4
Study type: Interventional

The primary purpose of this study is to evaluate the health care resource utilization and work status of patients with ankylosing spondylitis undergoing treatment with etanercept by comparing study evaluations with the baseline evaluations in the ASCEND (0881A3-402)(NCT00247962) study.

NCT ID: NCT00410033 Completed - Diabetes Clinical Trials

Comparison of Antibody Levels in Children and Adolescents After Initiation of Insulin Therapy by Either Insulin Aspart or Soluble Human Insulin

Start date: December 1989
Phase: N/A
Study type: Interventional

This trial is conducted in Europe. This is a single-centre, retrospective trial aiming at comparing the antibody levels in children and adolescents.

NCT ID: NCT00409617 Completed - Crohn's Disease Clinical Trials

Study of Adalimumab Treatment for Induction and Maintenance of Clinical Remission in Subjects With Crohn's Disease

Start date: December 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety of adalimumab for treatment of patients with moderate to severe Crohn's Disease (CD) and to measure the effects of treatment on patient general well-being, health-related quality of life (QoL), fistula healing, CD-related extra-intestinal manifestations, work performance, and overall activity.

NCT ID: NCT00409578 Completed - Myocardial Ischemia Clinical Trials

Efficacy and Safety of Aliskiren and Valsartan Versus Placebo in Patients Stabilized Following an Acute Coronary Syndrome

Start date: February 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the hypothesis that the inhibition of the renin-angiotensin-aldosterone system (RAAS) with the angiotensin receptor blocker valsartan or the renin antagonist aliskiren will improve ventricular hemodynamics, as reflected by a greater reduction in levels of N-terminal proB-type natriuretic peptide (NT-proBNP) compared to placebo in subjects stabilized following acute coronary syndrome (ACS) who are determined to be at high risk due to an elevated concentration of natriuretic peptides.

NCT ID: NCT00409188 Completed - Clinical trials for Non-small Cell Lung Cancer

Cancer Vaccine Study for Unresectable Stage III Non-small Cell Lung Cancer (START)

START
Start date: January 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the cancer vaccine tecemotide (L-BLP25) in addition to best supportive care is effective in prolonging the lives of subjects with unresectable stage III non-small cell lung cancer, compared to best supportive care alone. A local ancillary (sub) study in European centers will evaluate the immune response in peripheral blood after tecemotide (L-BLP25) or placebo vaccination.