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NCT ID: NCT02371967 Completed - Clinical trials for Basal Cell Carcinoma

A Study to Assess the Effectiveness and Safety of Vismodegib (Erivedge®) in Participants With Advanced Basal Cell Carcinoma (BCC)

ROSETT
Start date: April 8, 2015
Phase:
Study type: Observational

This prospective, observational, cohort study is designed to assess the effectiveness and safety outcomes of vismodegib and to assess actual day-to-day disease and participant management by the physician.

NCT ID: NCT02371629 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

A Study of the Efficacy and Safety of NVA237 in Patients With Moderate to Severe COPD

Start date: June 24, 2015
Phase: Phase 4
Study type: Interventional

This study is a post-authorization commitment to the European Medicines Agency (EMA). The study serves to determine whether the treatment of patients with stable, symptomatic Chronic Obstructive Pulmonary Disease (COPD) with the investigational drug NVA237 is efficient and safe. The efficacy and safety of the drug was tested for twice daily dosing against once daily dosing.

NCT ID: NCT02371330 Completed - Thrombocytopenia Clinical Trials

The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia Study

Neo-HAT
Start date: April 2015
Phase: N/A
Study type: Observational

This is a prospective longitudinal study that evaluates Platelet Function Analyzer-100 (PFA-100) CT-ADPs (closure time-ADP) and incidence of bleeding using the Neonatal Bleeding Assessment Tool - Neo-BAT in preterm neonates <32 weeks gestational age or with a birth weight <1500 grams and with different degrees of thrombocytopenia. The investigators hypothesized that PFA-100 CT-ADP, a global in vitro test of primary hemostasis, will be a better predictor of clinical bleeding in neonates than platelet count alone. A bleeding risk assessment marker could help physicians more accurately determine the risk/benefit ratio of platelet transfusions, guiding platelet transfusion decisions in neonates with thrombocytopenia.

NCT ID: NCT02370966 Completed - Inflammation Clinical Trials

Berry Intake - Effects on Systemic and Oral Inflammation

Start date: February 2015
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine whether intake of berry powder effective in the treatment of systemic and oral inflammation.

NCT ID: NCT02370537 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study to Investigate How Common Pancreatic Exocrine Insufficiency (PEI) is in Patients With Type 2 Diabetes and Also to Investigate the Uptake of a Single Dose of EPANOVA® or OMACOR® in Patients With Different Degrees of PEI

PRECISE
Start date: March 2015
Phase: Phase 2
Study type: Interventional

This study is a 2-part open-label, randomized, crossover, multicenter, non-therapeutic Phase II study to investigate the presence of pancreatic exocrine insufficiency (PEI) in patients with Type 2 diabetes mellitus (T2DM), and to investigate the pharmacokinetics (PK) of EPANOVA® (omega-3 carboxylic acids) and omega-3-acid ethyl esters (OMACOR®, Abbott Healthcare Products Ltd) following a single oral dose in patients with different degrees of PEI.

NCT ID: NCT02369731 Active, not recruiting - Clinical trials for Muscular Dystrophy, Duchenne

Registry of Translarna (Ataluren) in Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)

Start date: April 30, 2015
Phase:
Study type: Observational [Patient Registry]

This study is being performed as a post-approval safety study (PASS), per the Pharmacovigilance Risk Assessment Committee (PRAC) of the European Medicines Agency (EMA), to gather data on Translarna (ataluren) safety, effectiveness, and prescription patterns in routine clinical practice.

NCT ID: NCT02369562 Completed - Clinical trials for Periodontal Bone Loss

A Retrospective Analysis of Failures of Oral Implants

Start date: September 2014
Phase:
Study type: Observational

The purpose of this retrospective study is to investigate and identify factors associated with the failure of dental implants within the population rehabilitated with dental implants at the Folktandvården Specialistklinik in Malmö (Spårvägsgatan 12, 214 27, Malmö).

NCT ID: NCT02366650 Recruiting - Sepsis Clinical Trials

Help in the Emergency Room to Detect Organ Dysfunction

HERO
Start date: February 2015
Phase: N/A
Study type: Observational

The purpose of this prospective, non-interventional clinical study is to assess the clinical validity of a number of markers (including Heparin Binding Protein (HBP), Procalcitonin (PCT), C-reactive protein (CRP), White cell count (WCC) and lactate) for indicating the presence of organ dysfunction, or outcome, of patients with organ dysfunctions following emergency department admission or hospitalization. Secondary objectives are to identify novel putative biomarkers and to identify risk factors for negative long-term effects of acute critical illness The HBP assay is an enzyme-linked immunosorbent assay (ELISA) for the quantitative determination of Heparin Binding Protein in human plasma.

NCT ID: NCT02366585 Completed - Periodontitis Clinical Trials

The Effect of Locally Delivered Ciclosporin as an Adjunct to Healing After Treatment of Periodontal Pockets

Start date: March 2015
Phase: Phase 2
Study type: Interventional

The main purpose of the trial is to investigate the effect of locally delivered ciclosporin as an adjunct to non-surgical mechanical debridement in the treatment of chronic periodontitis and to compare it to mechanical debridement alone.

NCT ID: NCT02366429 Completed - Clinical trials for Antenatal Depression

ICBT for Antenatal Depression

Start date: February 2015
Phase: N/A
Study type: Interventional

Randomized controlled trial evaluating an Internet-delivered Cognitive Behavioral Therapy (ICBT) adapted for pregnant women suffering from antenatal depression. The ICBT-program will be added to treatment as usual (TAU) and compared to TAU only. Participants (n=60) are recruited from all over Sweden (only Swedish citizens can participate) and are assessed and treated on a distance via a secure web platform and telephone.