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NCT ID: NCT00878709 Completed - Breast Cancer Clinical Trials

Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast Cancer

ExteNET
Start date: July 9, 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate whether neratinib can further reduce the risk of recurrence from previously diagnosed HER-2 positive breast cancer after adjuvant treatment with trastuzumab.

NCT ID: NCT00878618 Completed - Healthy Clinical Trials

Pharmacokinetics of Extended-Release Test- and Reference Formulations of AZD0837

Start date: April 2009
Phase: Phase 1
Study type: Interventional

The aims of this study are to evaluate the pharmacokinetics, safety and tolerability of the oral doses of the extended-release test- and reference formulations of AZD0837 in healthy volunteers both in fasting and fed conditions.

NCT ID: NCT00877981 Completed - Clinical trials for Primary Hyperparathyroidism

Open Versus Video-Assisted Minimal-Invasive Parathyroid Surgery

Start date: February 2003
Phase: N/A
Study type: Interventional

The aim of the present study was to compare open minimal-invasive parathyroid surgery with video-assisted parathyroidectomy in primary hyperparathyroidism (PHPT) patients with a positive sestamibi scan in a multicentre randomized trial in order to evaluate if videoassisted surgery gave less postoperative pain and if there was a difference in operating time.

NCT ID: NCT00877929 Completed - Hypertension Clinical Trials

Telmisartan Fixed Dose Combination vs Amlodipine in Hypertensive Patients With Type 2 Diabetes Mellitus

Start date: February 2009
Phase: Phase 3
Study type: Interventional

To demonstrate that the fixed dose combination of telmisartan and amlodipine is more effective in lowering blood pressure.

NCT ID: NCT00877058 Completed - Clinical trials for Frail Elderly Persons

SUPPORT FOR FRAIL ELDERLY PERSONS - From Prevention to Palliation

Start date: January 2008
Phase: N/A
Study type: Interventional

The present study "Elderly person in the risk zone" form part of the research programme "Support for frail elderly persons - from prevention to palliation" (www. Vardalinstitutet.net) which comprises research into three interventions. A fundamental principle in the research programme is that it comprises interventions addressing frail elderly person in different phases of the disablement process, from elderly persons who are beginning to develop frailty to very frail elderly persons receiving palliative care in the final period of their lives. The interventions also address the different requirements that arise with regard to professional contributions during the various phases of the ageing and disease process, ranging from health promotion to a need for an increasing degree of medical care, nursing, special care and rehabilitation, and finally, efforts that promote symptom relief, quality of life, security and satisfaction with care during the final period of life. The intervention "Elderly persons in the risk zone" addresses elderly persons that are on the point of developing frailty ("pre-frail") and are beginning to feel that they are being hindered from taking part in everyday activities. The hypothesis is that if an intervention is made when the persons are not so frail, it is possible to prevent/delay deterioration. 1. Can a health-promoting and preventive intervention for "prefrail" elderly persons: - prevent frailty, activity limitations and morbidity, - be a supportive factor in the social and physical environment, - affect life satisfaction - have an impact on the consumption of care - be cost-effective? 2. How do the frail elderly persons experience the intervention and its importance to health?

NCT ID: NCT00876785 Completed - Obesity Clinical Trials

Effect of Rye Bread Breakfasts on Eight Hour Satiety Ratings

Start date: September 2007
Phase: N/A
Study type: Interventional

The aim of the present study was to investigate subjective appetite during 8 hours after intake of iso-caloric rye bread breakfasts varying in dietary fiber composition and content.

NCT ID: NCT00876421 Completed - Overactive Bladder Clinical Trials

Study of ONO-8539 in Patients With Overactive Bladder

Start date: April 2009
Phase: Phase 2
Study type: Interventional

The objective of this study is to investigate efficacy, safety and tolerability of ONO-8539 in patients with overactive bladder.

NCT ID: NCT00876057 Completed - Hysterectomy Clinical Trials

Psychological Well-being, Recovery and Sexuality After Total and Subtotal Hysterectomy

Start date: March 1998
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether psychological well-being, recovery and sexuality differs in women undergoing subtotal and total abdominal hysterectomy. Se also Detailed Description for additional study.

NCT ID: NCT00876031 Completed - Soft Tissue Sarcoma Clinical Trials

Trial for Localised High-risk Rhabdomyosarcoma and Rhabdomyosarcoma-like Soft Tissue Sarcoma

CWS-2007-HR
Start date: July 1, 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate whether the addition of oral maintenance chemotherapy with O-TIE (Etoposide, Idarubicin, Trofosfamide) for 6 months improves the event free survival (EFS) in patients with localised high-risk RMS and RMS-like Soft Tissue Sarcoma.

NCT ID: NCT00875667 Completed - Clinical trials for Mantle Cell Lymphoma

A Study to Determine the Efficacy of Lenalidomide Versus Investigator's Choice in Patients With Relapsed or Refractory Mantle Cell Lymphoma (MCL)

Sprint
Start date: April 30, 2009
Phase: Phase 2
Study type: Interventional

To evaluate the safety and efficacy of lenalidomide versus investigator choice in patients with relapsed or refractory mantle cell lymphoma.