Clinical Trials Logo

Filter by:
NCT ID: NCT01642004 Completed - Clinical trials for Squamous Cell Non-small Cell Lung Cancer

Study of BMS-936558 (Nivolumab) Compared to Docetaxel in Previously Treated Advanced or Metastatic Squamous Cell Non-small Cell Lung Cancer (NSCLC) (CheckMate 017)

Start date: October 16, 2012
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare the overall survival of BMS-936558 as compared with Docetaxel in subjects with squamous cell non-small cell lung cancer (NSCLC), after failure of prior platinum-based chemotherapy.

NCT ID: NCT01639339 Completed - Lupus Nephritis Clinical Trials

Efficacy and Safety of Belimumab in Patients With Active Lupus Nephritis

BLISS-LN
Start date: July 12, 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy, safety, and tolerability of belimumab in adult patients with active lupus nephritis.

NCT ID: NCT01639014 Completed - Ischemic Stroke Clinical Trials

Effect of F2695 on Functional Recovery After Ischemic Stroke

LIFE
Start date: July 2012
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the efficacy of a new serotonin-norepinephrine reuptake inhibitor (SNRI) nin functional recovery after ischemic stroke.

NCT ID: NCT01638923 Completed - Metrorrhagia Clinical Trials

Study of a 4-phasic Oral Contraceptive for the Treatment of Heavy Menstrual Bleeding

Start date: June 2012
Phase: Phase 3
Study type: Interventional

To evaluate efficacy and safety of a combined oral contraceptive of estradiol valerate and dienogest in the treatment of heavy menstrual bleeding

NCT ID: NCT01638715 Completed - Clinical trials for Rheumatoid Arthritis

A Randomized, Multi-Center Biomarker Trial to Predict Therapeutic Responses of Patients With Rheumatoid Arthritis to a Specific Biologic Mode of Action

Start date: May 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to find biological response patterns of patients with rheumatoid arthritis to drugs with different biologic modes of action. This study should help to predict therapeutic responses and to find the right therapy for the right patient.

NCT ID: NCT01638000 Completed - Urologic Diseases Clinical Trials

A Study to Evaluate the Efficacy and Safety of Mirabegron Compared to Solifenacin in Patients With Overactive Bladder Who Were Previously Treated With Another Medicine But Were Not Satisfied With That Treatment.

BEYOND
Start date: June 12, 2012
Phase: Phase 3
Study type: Interventional

The purpose of the study was to assess the efficacy, safety and tolerability of mirabegron 50 mg versus (vs) solifenacin 5 mg in the treatment of patients with OAB who were dissatisfied with their treatment due to lack of efficacy.

NCT ID: NCT01635998 Completed - Atrial Fibrillation Clinical Trials

Adjunctive Renal Denervation in the Treatment of Atrial Fibrillation

H-FIB
Start date: September 17, 2012
Phase: N/A
Study type: Interventional

The objective of the H-FIB trial is to determine the role of renal sympathetic denervation in the prevention of Atrial Fibrillation (AF) recurrence in patients with hypertension for whom a catheter-based AF ablation procedure is planned. Patients will be randomized to either AF catheter ablation (usual therapy) or AF catheter ablation plus renal sympathetic denervation.

NCT ID: NCT01634152 Completed - Asthma Clinical Trials

Efficacy and Safety of 2 Doses of Tiotropium Respimat® Compared to Placebo in Children With Severe Persistent Asthma

Start date: July 2012
Phase: Phase 3
Study type: Interventional

The overall purpose of the trial is to evaluate efficacy and safety of tiotropium inhalation solution (2.5 mcg and 5 mcg) delivered via Respimat® inhaler once daily in the evening over 12 weeks, compared to placebo, as add-on controller therapy on top of usual care in children (6 to 11 years old) with severe persistent asthma.

NCT ID: NCT01634139 Completed - Asthma Clinical Trials

Efficacy and Safety of 2 Doses of Tiotropium Respimat® Compared to Placebo in Children With Moderate Persistent Asthma

Start date: July 2012
Phase: Phase 3
Study type: Interventional

The overall purpose of the trial is to evaluate efficacy and safety of tiotropium inhalation solution delivered via Respimat® inhaler (2.5 mcg and 5 mcg once daily in the evening) over 48 weeks, compared to placebo, in children (6 to 11 years old) with moderate persistent asthma.

NCT ID: NCT01632163 Completed - Clinical trials for Type 2 Diabetes Mellitus

Assessment of the Efficacy and Safety of Lixisenatide in Patients With Type 2 Diabetes Insufficiently Controlled With Basal Insulin +/- Metformin

Start date: October 2012
Phase: Phase 3
Study type: Interventional

Primary Objective: - To assess the effects on glycemic control of lixisenatide in comparison to placebo as an add-on treatment to basal insulin with or without metformin in terms of HbA1c reduction over a period of 24 weeks in insufficiently controlled type 2 diabetic patients. Secondary Objectives: - To assess the effects of lixisenatide over 24 weeks on : - percentage of patients reaching HbA1c<7% or ≤6.5%, - 2-hour postprandial plasma glucose (PPG) and plasma glucose (PG) excursions during standardized meal challenge test, - fasting plasma glucose (FPG), - change in 7-point self-monitored plasma glucose (SMPG) profile), - body weight, - change in daily basal insulin dose. - To assess lixisenatide safety and tolerability. - To assess anti-lixisenatide antibody development.