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NCT ID: NCT00240383 Completed - Clinical trials for Diabetes Mellitus II

Dose Ranging Study With LT, Monotherapy, PPAR

Start date: May 2002
Phase: Phase 2/Phase 3
Study type: Interventional

A Randomized, Double-Blind, Dose-Ranging, Dose Comparison-Controlled Trial to Determine the Safety and Efficacy of BMS-298585 in Subjects with Type 2 Diabetes

NCT ID: NCT00240370 Completed - Type 2 Diabetes Clinical Trials

A Study to Evaluate Combining Metformin With Muraglitazar or Pioglitazone in Type 2 Diabetics

Start date: October 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate if type 2 diabetics who have inadequate glycemic control on metformin alone, have a similar, or not inferior, glycemic response when treated with the combination of muraglitazar and metformin compared to pioglitazone and metformin.

NCT ID: NCT00238264 Completed - Brain Tumor Clinical Trials

Radiation Therapy in Treating Young Patients With Gliomas

Start date: November 2006
Phase: Phase 2
Study type: Interventional

RATIONALE: Specialized radiation therapy that delivers radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. PURPOSE: This phase II trial is studying how well radiation therapy works in treating young patients with gliomas.

NCT ID: NCT00236093 Completed - Pain Clinical Trials

Extension Study of ACTIQ Treatment for Children and Adolescents With Breakthrough Pain

Start date: October 2006
Phase: Phase 2
Study type: Interventional

The objective of the study is to monitor the safety (adverse event data) of longer-term use of ACTIQ (Oral Transmucosal Fentanyl Citrate [OTFC]) treatment in children with pain associated with cancer, sickle cell disease, or severe burns and breakthrough pain (BTP) who are receiving around the clock (ATC) opioid therapy.

NCT ID: NCT00236041 Completed - Cancer Clinical Trials

Efficacy/Safety Study of ACTIQ® for Opioid-Tolerant Children and Adolescents With Breakthrough Pain (BTP)

Start date: April 2004
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to evaluate the efficacy of ACTIQ treatment for the management of breakthrough pain (BTP) compared to placebo treatment in children with cancer and non-cancer pain who are receiving around-the-clock (ATC) opioid therapy and who require additional therapy for BTP episodes. This will be determined by the analysis of the pain intensity (PI), measured by the Faces Pain Scale-Revised (FPS-R) administered 15 minutes after the start of each unit of study drug with an optimal ACTIQ dosage.

NCT ID: NCT00235716 Completed - Alzheimer's Disease Clinical Trials

A Randomized, Clinical Trial of Vitamin E and Memantine in Alzheimer's Disease

TEAM-AD
Start date: August 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether alpha-tocopherol, memantine (Namenda), or the combination will significantly delay clinical progression in mild to moderately demented patients with Alzheimer's disease compared to placebo.

NCT ID: NCT00234975 Completed - HIV Infection Clinical Trials

Safety of Lopinavir/Ritonavir (Kaletra) in HIV/HCV Co-infected Subjects vs Baseline Liver Biopsy Metavir Score

Start date: October 2002
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate clinical response and safety of a Kaletra containing antiretroviral treatment regimen in HIV positive subjects with HCV coinfection.

NCT ID: NCT00234117 Completed - Clinical trials for Gastroesophageal Reflux

Improvement in Bronchial Asthma in Patients With Extraesophageal Reflux After Acid Suppression

Start date: July 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if 20mg BID of Rabeprazole is effective in controlling GERD in patients with concomitant bronchial asthma and to assess improvement in asthma after reflux control.

NCT ID: NCT00233025 Completed - Fibromyalgia Clinical Trials

Duloxetine Versus Placebo in the Treatment of FMS

Start date: September 2005
Phase: Phase 3
Study type: Interventional

To test the hypothesis that the efficacy and safety of duloxetine has beneficial effects of the reduction of pain severity as measured by the average pain item of the BPI and the PGI-I in patients with fibromyalgia syndrome.

NCT ID: NCT00232908 Completed - HIV Infections Clinical Trials

QUALITE Study - A Study of Fuzeon (Enfuvirtide) in Treatment-Experienced Patients With Human Immunodeficiency Virus-1 (HIV-1) Infection

Start date: June 2004
Phase: Phase 4
Study type: Interventional

This study will evaluate patient quality of life and tolerability of a HAART (highly active antiretroviral therapy) regimen containing twice-daily subcutaneous injections of Fuzeon in clinically stable, treatment-experienced patients with HIV-1 infection. All patients will use a 31-gauge thin-walled 8mm needle to administer Fuzeon. The anticipated time on study treatment is 3-12 months, and the target sample size is 100-500 individuals.