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NCT ID: NCT00676754 Active, not recruiting - Clinical trials for TB Multi-drug Resistant

Epidemiology of MDR-TB in Peru

Estudio Epi
Start date: September 2009
Phase: Phase 4
Study type: Observational

The purpose of this study is to better understand tuberculosis (TB) and the risk of infection with TB, in Peru. TB is a disease that is caused by bacteria and transmitted through droplets in the air that come from the lungs of an infected person. The risk of infection will be compared between two groups: household members, who live with people having TB that does not respond well to treatment and household members, who live with people having TB that responds well to treatment. Study participants will include 4,500 TB infected people and 22,500 of their household contacts. Study procedures include answering a questionnaire, TB skin tests, blood samples, and a chest x-ray. Individuals with symptoms indicating TB will be asked to provide sputum samples. Individuals with TB will be involved in the study for up to 48 months; household contacts will be involved in the study for 12 months. The knowledge gained from this study will be used to improve tuberculosis control.

NCT ID: NCT00676650 Terminated - Prostatic Neoplasms Clinical Trials

Sunitinib Plus Prednisone In Patients With Metastatic Castration-Resistant Prostate Cancer After Failure Of Docetaxel Chemotherapy

SUN 1120
Start date: July 2008
Phase: Phase 3
Study type: Interventional

This study will compare the safety and efficacy of sunitinib in combination with prednisone versus placebo and prednisone in patients that have metastatic castration-resistant prostate cancer that has progressed after treatment with a docetaxel-containing chemotherapy regimen. This is a second-line study.

NCT ID: NCT00674973 Completed - Pancreatic Cancer Clinical Trials

A Biomarker Identification Trial of Tarceva (Erlotinib) in Patients With Advanced Pancreatic Cancer

Start date: June 2008
Phase: Phase 2
Study type: Interventional

This study is designed to identify biomarkers which may predict improvement in progression free survival from treatment with Tarceva, in patients with advanced pancreatic cancer who failed one prior regimen of standard chemotherapy or who are deemed unsuitable for chemotherapy. It will also assess the efficacy and safety of Tarceva in this patient population. Patients will be randomized to receive either Tarceva 150mg/day po, or placebo po daily. Tumor tissue will be used for biomarker analysis. The anticipated time on study treatment is until disease progression, and the target sample size is 100-500 individuals.

NCT ID: NCT00671320 Completed - Pain Clinical Trials

A Multi-Center, Randomized, Double-Blind, Parallel Group Study To Compare The Efficacy And Tolerability Of Valdecoxib And Diclofenac In Patients With A Sprained Ankle

Start date: December 2002
Phase: Phase 4
Study type: Interventional

To determine whether valdecoxib 40 mg twice a day the first day and then 40mg once a day until Day 7, was at least as effective as diclofenac 75 mg twice a day for 7 days, in treating acute first or second degree ankle sprain. The study also compared valdecoxib and diclofenac with respect to time to onset of pain relief (measured after the first dose), tolerability (adverse events) and time to return to Normal Function/Activity, among other measures.

NCT ID: NCT00670163 Completed - HIV Infections Clinical Trials

Effectiveness of Community-Level Behavioral and Biomedical Interventions for Reducing HIV/STIs in Men in Peru

Start date: April 2008
Phase: N/A
Study type: Interventional

This study will evaluate the effectiveness of community-level behavioral and biomedical interventions, each alone and combined, in reducing sexual risk behavior and HIV/sexually transmitted infections in Peruvian men who have sex with men.

NCT ID: NCT00668109 Completed - Clinical trials for Erectile Dysfunction

Assessment of Efficacy of Vardenafil in Subjects With Erectile Dysfunction and Diabetes, Hypertension or Hyperlipidemia

LUTECIA
Start date: December 2003
Phase: Phase 3
Study type: Interventional

Assessment of efficacy of vardenafil in subjects with erectile dysfunction and diabetes, hypertension or hyperlipidemia

NCT ID: NCT00667823 Completed - Clinical trials for Pulmonary Arterial Hypertension

Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension

SERAPHIN OL
Start date: October 17, 2008
Phase: Phase 3
Study type: Interventional

The main objective of the AC 055 303/SERAPHIN OL study, which will follow the AC 055 302/SERAPHIN study, will be to assess the long-term safety and tolerability of ACT 064992 in patients with symptomatic PAH.

NCT ID: NCT00666185 Completed - Candidiasis, Oral Clinical Trials

Comparative Trial of Micafungin Versus Fluconazole for Treating Esophageal Candidiasis

Start date: August 2003
Phase: Phase 3
Study type: Interventional

To determine the efficacy and safety of IV Micafungin versus IV Fluconazole in the treatment of patients with Esophageal Candidiasis

NCT ID: NCT00665639 Completed - Candidiasis, Oral Clinical Trials

Trial of Two Dosing Regimens of Micafungin Versus Caspofungin for the Treatment of Esophageal Candidiasis

Start date: June 2004
Phase: Phase 3
Study type: Interventional

To determine the efficacy and safety of daily doses of IV micafungin versus IV caspofungin for the treatment of esophageal candidiasis

NCT ID: NCT00665626 Completed - Clinical trials for Rheumatoid Arthritis

Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis (Taski-3)

Taski-3
Start date: May 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether the Spleen Tyrosine Kinase (Syk) Inhibitor, R935788 (R788) at a dose of 100 mg, tablet, orally, twice-a-day is effective in the treatment of Rheumatoid Arthritis in patients who have 'failed' a biologic therapy.