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NCT ID: NCT02332304 Completed - Clinical trials for Respiratory Distress Syndrome, Newborn

Amniotic Fluid Optical Density Determination as a Test for Assessment of Fetal Lung Maturity.

Start date: May 2014
Phase: Phase 3
Study type: Interventional

To determine the relationship between the result of amniotic fluid optical density between 26 and 36 6/7 weeks of pregnancy and the risk of developing neonatal respiratory distress syndrome.

NCT ID: NCT02332278 Completed - Clinical trials for Complications; Cesarean Section

Early Oral Feeding Versus Traditional Postoperative Care After Cesarean Section.

Start date: June 2014
Phase: N/A
Study type: Interventional

To determine the effect in the post operative period of early feeding (4 hours after surgery) vs. traditional management (feeding 12 hours after surgery) in uncomplicated cesarean section.

NCT ID: NCT02332252 Completed - Clinical trials for Surgical Wound Infection

Electrocautery Versus Scalpel for Surgical Skin Incisions in Cesarean Section.

Start date: August 2015
Phase: N/A
Study type: Interventional

To determine the risk of surgical site infection after surgical skin incision, comparing electrocautery vs. scalpel.

NCT ID: NCT02331550 Completed - Clinical trials for LSIL, Low-Grade Squamous Intraepithelial Lesions

Observational vs. Ablative Treatment for Low-grade Squamous Intraepithelial Lesions.

Start date: January 2014
Phase: N/A
Study type: Interventional

To evaluate the rate of regression and progression of low-grade squamous intraepithelial lesion comparing expectant vs. ablative treatment.

NCT ID: NCT02325791 Completed - Clinical trials for Respiratory Syncytial Virus Infections

Study to Evaluate the Efficacy and Safety of Suptavumab (REGN2222) for the Prevention of Medically Attended RSV (Respiratory Syncytial Virus) Infection in Preterm Infants

Start date: July 21, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the efficacy, safety, pharmacokinetics (PK), and immunogenicity of suptavumab (REGN2222) in infants born no more than 35 weeks, 6 days gestational age who are no more than 6 months of age at the time of enrollment in their respective geographic location. In order to optimize the potential benefit in this vulnerable population, we conducted this study during the RSV season using dosing regimens that are expected to be effective.

NCT ID: NCT02322762 Completed - Clinical trials for Type 2 Diabetes Mellitus

DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Settings

DISCOVER
Start date: December 30, 2014
Phase:
Study type: Observational

DISCOVER is a Non Interventional Study study to describe the disease management patterns and clinical evolution over three years in type 2 diabetes mellitus patients initiating a second line anti-diabetic treatment.

NCT ID: NCT02317146 Completed - Clinical trials for Severe Pre-eclampsia With Postnatal Complication

Magnesium Sulfate in Pregnancy and Postpartum

MAG-PP
Start date: November 2013
Phase: Phase 2/Phase 3
Study type: Interventional

There are huge doubts as to how long to keep postpartum magnesium sulfate. Studies demonstrating the usefulness for 24, 12 or 6 hours are of little evidence and do not take into account the use of magnesium sulphate before delivery. Termination of pregnancy is the best option to prevent eclampsia and magnesium sulphate has proven effective, but do not know the minimum effective dose.The investigators believe that if the patient has received less than 8 continuous hours of magnesium sulphate before delivery, maintain magnesium sulfate for 6 hours is as effective as keeping it for 24 hours.

NCT ID: NCT02307201 Completed - Clinical trials for Post Partum Severe Preeclampsia

Magnesium Sulfate During the Postpartum in Women With Severe Preeclampsia

MAG-PIP
Start date: December 2014
Phase: Phase 2/Phase 3
Study type: Interventional

There is no evidence that patients receiving magnesium sulfate before birth are required to maintain the drug for 24 hours. Therefore the investigators will have a randomized clinical study in patients with severe preeclampsia who have been treated with impregnation of magnesium sulphate and at least eight hours have received the drug before birth. If the patient agrees and signs the consent is randomized to: 1-receive sulfate for 24 hours postpartum as usual or, 2- not receiving the postpartum magnesium sulfate or other anticonvulsant drugs. This study can be conducted in 12 maternity latin america.

NCT ID: NCT02302066 Completed - Dengue Fever Clinical Trials

Safety and Immunogenicity of Different Schedules of Takeda's Tetravalent Dengue Vaccine Candidate (TDV) in Healthy Participants

Start date: December 5, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the humoral immune responses to three different dose schedules of Takeda's Tetravalent Dengue Vaccine Candidate (TDV) administered subcutaneously in healthy participants between 2 and <18 years of age living in dengue endemic countries.

NCT ID: NCT02273973 Completed - Breast Cancer Clinical Trials

A Study of Neoadjuvant Letrozole + Taselisib Versus Letrozole + Placebo in Post-Menopausal Women With Breast Cancer (LORELEI)

Start date: November 12, 2014
Phase: Phase 2
Study type: Interventional

This is a two-arm, randomized, double-blind, multicenter, pre-operative study to evaluate the effect of combining letrozole and GDC-0032 (also known as taselisib) versus letrozole and placebo in postmenopausal women with estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2 (HER2) untreated, Stage I-III operable breast cancer. Participants will be randomized into one of the two treatment arms with a 1:1 randomization ratio. Letrozole at 2.5 milligrams (mg) will be dosed once daily plus either Taselisib at 4 mg (two 2-mg tablets) or placebo on a 5 days-on/ 2 days-off schedule for a total of 16 weeks.