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NCT ID: NCT05567757 Recruiting - Clinical trials for End Stage Renal Disease

Initial Safety Study of the TRUE AVC in Hemodialysis Access (TRUE AVC I Study)

Start date: October 4, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Prospective, nonrandomized, single-arm, single-center, open-label, initial safety study in subjects requiring hemodialysis. Subjects will be followed with physical evaluation and ultrasound vessel imaging at days 15, 29, 57 and weeks 12, 26. Extended follow up on patent conduits only at weeks 52 and 104.

NCT ID: NCT05542082 Recruiting - Clinical trials for Obstructive Sleep Apnea of Adult

Pilot Study of the CHILLS Cryotherapy System for the Treatment of OSA

ARCTIC-2
Start date: August 1, 2022
Phase: N/A
Study type: Interventional

This is a prospective, multicenter, non-randomized single-arm safety and efficacy study to: - Collect data to evaluate the safety of CHILLS cryotherapy to treat OSA in patients with moderate to severe disease. - Evaluate the chronic performance of the CHILLS system and collect clinical measures for therapy effectiveness that will be used to demonstrate safety and effectiveness in the next clinical study.

NCT ID: NCT05522296 Active, not recruiting - Mpox Clinical Trials

Break-through Infection Following Mpox vaccinatIon

REMAIN
Start date: September 1, 2022
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to assess the protection of smallpox preexposure vaccination against infection with mpox in real-world individuals with risk factors for mpox.

NCT ID: NCT05447988 Recruiting - Breast Cancer Clinical Trials

Motiva Flora Tissue Expander PMCF

Start date: December 14, 2020
Phase: N/A
Study type: Interventional

The Motiva Flora® Tissue Expander clinical study (hereafter Motiva Flora® TE study) is a 6-month, open-label, prospective, multicentre post-marketing follow-up study designed to confirm the Safety and Effectiveness/Performance of Motiva Flora® TE in breast reconstruction surgery. The study will include 136 women, planned for staged breast reconstruction, in 6 countries (Spain, Belgium, France, Costa Rica, Chile and Panama). Breast tissue expansion and the final breast implant will be performed using devices from the Motiva Flora® TE catalogue.

NCT ID: NCT05432245 Enrolling by invitation - Cataract Clinical Trials

MINIject Implantation Combined With Cataract Surgery in Patients With POAG and Cataract

STAR-VI
Start date: January 18, 2023
Phase: N/A
Study type: Interventional

The study will assess safety and performance of MINIject implant in patients with open-angle glaucoma uncontrolled by topical hypotensive medications in conjunction with cataract surgery.

NCT ID: NCT05415462 Completed - Seasonal Influenza Clinical Trials

A Study of mRNA-1010 Seasonal Influenza Vaccine in Adults

Start date: June 6, 2022
Phase: Phase 3
Study type: Interventional

The primary objectives of this study are to evaluate the humoral immunogenicity of mRNA-1010 relative to that of an active comparator against vaccine-matched influenza A and B strains at Day 29, and to evaluate the safety and reactogenicity of mRNA-1010.

NCT ID: NCT05404490 Recruiting - Pain, Postoperative Clinical Trials

Efficacy of Bupivacain Local Infiltration for the Management of Pain During Cesarean Section

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

This study aims to evaluate the effect of local administration of bupivacain in the cesarean section incision for postoperative pain control, using the visual analogue pain scale (VAS) and assessing the need for rescue analgesia after surgery.

NCT ID: NCT05363761 Recruiting - Hypertension Clinical Trials

Arterial Ablation for the Treatment of Type 2 Diabetes Mellitus and Its Comorbidities

NECTAR III
Start date: April 19, 2022
Phase: Phase 1
Study type: Interventional

This study is assess the safety and performance of the Neurotronic Infusion catheter for treatment of patients with Type 2 Diabetes (T2DM) and hypertension.

NCT ID: NCT05317728 Recruiting - Cataract Clinical Trials

Clinical Study of a Fluid Accommodating Intraocular Lens (IOL) Design

Start date: March 31, 2023
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to evaluate the surgical, refractive, and visual outcomes with implantation of an investigational intraocular lens (IOL).

NCT ID: NCT05295641 Recruiting - Heart Failure Clinical Trials

American Registry of Ambulatory or Acute Decompensated Heart Failure

AMERICCAASS
Start date: April 1, 2022
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to better characterize and understand the population of patients with ambulatory or acutely decompensated heart failure in the American continent, getting to know their sociodemographic, clinical and paraclinical characteristics