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NCT ID: NCT00804375 Recruiting - Stump Pain Clinical Trials

Study of the Efficacy, Safety and Tolerability of Topical 2PX (Strontium Chloride Hexahydrate) in Patients With Chronic, Moderate-to-severe Lower Limb Post-amputation Stump Pain

Start date: December 2008
Phase: Phase 2
Study type: Interventional

Primary: To compare the analgesic effect over 12 weeks of topical 2PX in stump pain. Secondary: To prospectively measure other efficacy and safety variables of topical 2PX in stump pain. Exploratory analyses will be performed to measure efficacy and safety variables of topical 2PX in phantom pain

NCT ID: NCT00803049 Completed - Multiple Sclerosis Clinical Trials

Long Term Safety and Efficacy Study of Teriflunomide 7 mg or 14 mg in Patients With Relapsing-Remitting Multiple Sclerosis

Start date: October 2006
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to document the long-term safety and tolerability of teriflunomide in Multiple Sclerosis (MS) patients with relapse. The secondary objective is to document the long-term efficacy on disability progression, relapse rate and Magnetic Resonance Imaging (MRI) parameters.

NCT ID: NCT00802373 Completed - Clinical trials for Urinary Bladder, Overactive

Solifenacin Succinate Versus Tolterodine 4mg Once Daily

STAR
Start date: July 2003
Phase: Phase 3
Study type: Interventional

Prospective, double-blind, double-dummy, 2-arm, parallel-group, design. Flexible dose regimen for solifenacin succinate, fixed dose treatment regimen for tolterodine. Assessment of OAB symptoms by patient diaries.

NCT ID: NCT00800384 Completed - Clinical trials for Ventricular Tachycardia

Shockless Implant Evaluation

SIMPLE
Start date: January 2009
Phase: N/A
Study type: Interventional

This trial will assess the safety of defibrillator testing and the influence of defibrillation testing on the efficacy of clinical shocks. The trial will test the hypothesis that implantable cardioverter defibrillator (ICD) implantation without defibrillation testing (DT) is non-inferior to implantation with testing against the composite endpoint of ineffective first appropriate clinical shock or arrhythmic death. It will also test the hypothesis, that defibrillation testing increases the peri-operative (30 days) complication rate of ICD implantation.

NCT ID: NCT00800124 Completed - Hip Fracture Clinical Trials

Study on Cemented Versus Non-cemented Hemiarthroplasty in Elderly With Hip Fractures

CNC
Start date: June 2005
Phase: N/A
Study type: Interventional

The objective is to study the overall frequency and cumulative rate (during one year) of clinical morbidity (defined as any hospitalization without fatal outcome) and mortality in all consecutive patients undergoing HF surgery (pins and prosthetic implants) and compare this to the group of patients receiving prosthetic implants and further find out if there is a difference between the non-cemented and cemented groups. Between the same prosthetic groups, the investigators want to study the overall frequency of in-hospital subclinical organ damage and dysfunction of myocardium, liver and lungs, using biochemical plasma markers. Finally, the investigators want to perform perioperative cost benefit calculations and out of hospital quality of life analysis between the surgical groups.

NCT ID: NCT00799903 Completed - Atherosclerosis Clinical Trials

The Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy Trial

STABILITY
Start date: December 2008
Phase: Phase 3
Study type: Interventional

This study will test whether darapladib can safely lower the chances of having a cardiovascular event (such as a heart attack or stroke) in people with coronary heart disease.

NCT ID: NCT00798434 Completed - Clinical trials for Urinary Bladder, Overactive

A Study to Compare the Effectiveness and Safety of Fesoterodine and Placebo in an Elderly Population of Patients Who go to the Toilet Very Frequently Due to Overactive Bladder.

SOFIA
Start date: June 2008
Phase: Phase 4
Study type: Interventional

The drug being studied, fesoterodine fumarate helps prevent the bladder neck opening at unwanted times and has been shown to help patients with overactive bladder syndrome pass urine less frequently than before treatment. It is postulated that this drug will also prove effective in elderly patients (aged > 65 years) and that the ability to change dose between 4 and 8mg will allow each patient to have an optimised treatment.

NCT ID: NCT00797706 Active, not recruiting - Clinical trials for Chronic Venous Leg Ulcers

Phase I/II Dose Ranging CHRONSEAL® Study in Venous Leg Ulcers

Start date: November 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate if the investigational medicinal product CHRONSEAL intended for future treatment of chronic venous leg ulcers is safe and tolerated and if it has an ulcer size reduction effect when administered to individuals suffering from venous leg ulcers.

NCT ID: NCT00797641 Completed - Clinical trials for Gastrointestinal Hemorrhage

European Survey of Non-Variceal Upper Gastro Intestinal Bleeding (NVUGIB)

ENERGIB
Start date: January 2009
Phase: N/A
Study type: Observational

The aim of this study is to assess the current management strategies in a pan-European "real-life" setting to uncover the unmet need in this area: non-variceal gastrointestinal bleedings.

NCT ID: NCT00796653 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Safety and Efficacy of BI 1744 CL in Patients With Chronic Obstructive Pulmonary Disease II

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to assess the long-term efficacy and safety of once daily treatment of BI 1744 CL inhalation solution (5 and 10 mcg) delivered via the Respimat® inhaler, in patients with COPD.