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NCT ID: NCT02007343 Completed - Clinical trials for Gram-Negative Bacterial Infection

Burden of Antibiotic Resistance in Gram-Negative Infections in Dutch Hospitals

GRAND-ABC
Start date: June 2013
Phase:
Study type: Observational

This study aims to assess how large an additional disease burden and what extra costs are generated by antibiotic resistance in patients suffering from infections caused by gram-negative bacteria, such as Escherichia coli and Pseudomonas aeruginosa, in hospitals in the Netherlands.

NCT ID: NCT02007252 Terminated - Clinical trials for Abdominal Aortic Aneurysm (AAA)

ACZ885 for the Treatment of Abdominal Aortic Aneurysm

AAA
Start date: December 2013
Phase: Phase 2
Study type: Interventional

This study was designed to assess the safety, tolerability and efficacy of ACZ885 on aneurysmal growth rate in subjects with abdominal aortic aneurysms (AAA). The purpose of the study was to provide data to enable decisions regarding the further development of ACZ885 for subjects with abdominal aortic aneurysms. The design of this study addressed the primary objective of evaluating the change in aneurysmal size in subjects with AAA as a result of treatment with ACZ885.

NCT ID: NCT02006524 Completed - Atrial Fibrillation Clinical Trials

Screening for Silent Atrial Fibrillation During Influenza Vaccination

Start date: October 2013
Phase: N/A
Study type: Interventional

Silent atrial fibrillation is an important cause of unnecessary strokes. If diagnosed and treated in time with anticoagulants, many disabling strokes can be prevented. In order to improve the diagnosis of atrial fibrillation the MyDiagnostick is developed; a user friendly and easy to use stick that diagnoses atrial fibrillation in one minute. During influenza vaccination, many patients who are also at risk for atrial fibrillation visit the general practice. This offers an ideal opportunity for screening for atrial fibrillation. The study investigates the yield of screening for atrial fibrillation with the MyDiagnostick during influenza vaccination (newly detected atrial fibrillation with corresponding CHA2DS2-Vasc score).

NCT ID: NCT02006472 Completed - Clinical trials for Huntington's Disease

A Phase 2, to Evaluating the Safety and Efficacy of Pridopidine Vs Placebo for Symptomatic Treatment in Patients With Huntington's Disease

Start date: February 28, 2014
Phase: Phase 2
Study type: Interventional

This is a multicenter, multinational, randomized, parallel-group, double-blind, placebo-controlled, dose range finding study to compare the efficacy and safety of different doses of pridopidine versus placebo in the treatment of motor impairment in Huntington's Disease (HD).

NCT ID: NCT02006121 Completed - Parkinson's Disease Clinical Trials

Clinical Trial of Apomorphine Subcutaneous Infusion in Patients With Advanced Parkinson's Disease

TOLEDO
Start date: March 3, 2014
Phase: Phase 3
Study type: Interventional

The primary objective of the trial was to investigate the efficacy of apomorphine continuous subcutaneous infusion compared to placebo in Parkinson's Disease patients with motor fluctuations not well controlled on medical treatment. The secondary objective of the study was to investigate the safety and tolerability of apomorphine continuous subcutaneous therapy.

NCT ID: NCT02006069 Terminated - Heart Failure Clinical Trials

MOre REsponse on Cardiac Resynchronization Therapy With MultiPoint Pacing

MORE CRT MPP
Start date: December 2013
Phase: N/A
Study type: Interventional

The purpose of this Clinical investigation is to assess the impact of the Multi Point Pacing (MPP) feature at 12 months in the treatment of patients not responding to standard Cardiac Resynchronization Therapy (CRT) after 6 months.

NCT ID: NCT02005822 Completed - Clinical trials for Sensorineural Hearing Loss

Congenital Cytomegalovirus: Efficacy of Antiviral Treatment

CONCERT 2
Start date: October 22, 2013
Phase: Phase 3
Study type: Interventional

The objective of the trial is to investigate whether early treatment with oral valganciclovir of infants with both congenital cytomegalovirus infection and sensorineural hearing loss can prevent progression of hearing loss.

NCT ID: NCT02005731 Completed - Clinical trials for Vasculogenic Erectile Dysfunction

Low Intensity Extracorporeal Shockwave Therapy for Patients With Erectile Dysfunction

LISW
Start date: November 2012
Phase: N/A
Study type: Observational

This is a prospective, pilot study for assessing the safety and efficacy of the treatments performed with Renova (LI-ESWT) on symptomatic ED patients.

NCT ID: NCT02005471 Completed - Clinical trials for Chronic Lymphocytic Leukemia

A Study to Evaluate the Benefit of Venetoclax Plus Rituximab Compared With Bendamustine Plus Rituximab in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL)

MURANO
Start date: March 17, 2014
Phase: Phase 3
Study type: Interventional

The purpose of this open-label, multicenter, randomized, Phase III study is to evaluate the benefit of venetoclax in combination with rituximab compared with bendamustine in combination with rituximab in participants with relapsed or refractory CLL. Participants will be randomly assigned in 1:1 ratio to receive either venetoclax + rituximab (Arm A) or bendamustine + rituximab (Arm B).

NCT ID: NCT02005055 Completed - Keloid Clinical Trials

High Dose Rate Brachytherapy for Treatment of Keloids

Start date: January 2003
Phase: N/A
Study type: Observational

This prospective study evaluates the outcome of surgical excision with adjuvant high-dose-rate brachytherapy for the treatment of recalcitrant keloids. Main outcomes are recurrence rate, scar quality and physical complaints.