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NCT ID: NCT00823212 Completed - Clinical trials for Coronary Artery Disease

The PLATINUM Clinical Trial to Assess the PROMUS Element Stent System for Treatment of De Novo Coronary Artery Lesions

PLATINUM
Start date: January 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of the PROMUS Elementâ„¢ Everolimus-Eluting Coronary Stent System for the treatment of patients with up to 2 de novo atherosclerotic coronary artery lesions. This clinical trial compares outcomes in patients treated with PROMUS Element to those in patients treated with a different everolimus-eluting coronary stent. The lesions are of average length in average-sized vessels ("workhorse"). A companion sub-trial evaluates outcomes in smaller vessels (SV) and another sub-trial evaluates outcomes in longer lesions (LL).

NCT ID: NCT00822588 Completed - Clinical trials for Arthroplasty, Replacement, Hip

Comparison in Need for Bank Blood Between Patients Undergoing Total Hip Surgery That Either Receive Their Own Blood Back or Not

Start date: May 2009
Phase: N/A
Study type: Interventional

The study is a prospective, controlled, randomised and assessor blind study that investigate if the need for bank blood transfusion could be reduced in patients, undergoing primary or revision total hip replacement surgery, who receive their own blood back with the medical device Sangvia. A comparison in need for bank blood will be made between patients that either receive their own blood back or not.

NCT ID: NCT00821821 Completed - Clinical trials for Acute Ischemic Stroke (AIS)

Safety and Pharmacokinetics of MCI-186 in Subjects With Acute Ischemic Stroke

Start date: February 2009
Phase: Phase 2
Study type: Interventional

The objectives of this study are to assess the safety, tolerability and local tolerance, and to investigate the plasma levels and terminal elimination half life of MCI-186, and to review the routine clinical and neurological assessments data of MCI-186 in subjects with acute ischemic stroke.

NCT ID: NCT00821665 Completed - Type 2 Diabetes Clinical Trials

Blood Glucose Homeostasis in Type 2 Diabetes: the Effects of Saccharose

Start date: March 2007
Phase: N/A
Study type: Interventional

Hyperglycemia forms a direct and independent risk factor for the development of cardiovascular co-morbidities in type 2 diabetes. Consumption of sucrose-sweetened soft drinks might further increase the prevalence of hyperglycemic episodes. The objective of the study was to assess glycemic control in type 2 diabetes patients and healthy lean and obese controls under strict dietary standardization but otherwise free living conditions, with and without the consumption of soft drinks.

NCT ID: NCT00821379 Completed - Clinical trials for Pregnancy Complications

CoPPer Study - Complications of Polycystic Ovary Syndrome (PCOS) Pregnancy: Evaluating Risk

CoPPer
Start date: April 2008
Phase: N/A
Study type: Observational

The CoPPer study is a follow-up study of women diagnosed with Polycystic Ovary Syndrome (PCOS). Women will be included pre-conceptional and followed-up until after delivery. The investigators will design a multivariate prediction model of pregnancy outcome in women with PCOS with the intention to define intervention strategies for the future.

NCT ID: NCT00821054 Completed - Neoplasms, Breast Clinical Trials

A Study to Examine the Effects of Low and High-fat Meals on Orally Administered Lapatinib in Metastatic ErbB2 Positive Breast Cancer Patients

Start date: March 6, 2009
Phase: Phase 1
Study type: Interventional

This study will be a randomized 3-treatment, cross-over study to evaluate the bioavailability of lapatinib administered after a high or low-fat meal.

NCT ID: NCT00820911 Completed - Clinical trials for Kidney Transplantation

Efficacy and Safety of AEB071 Versus Cyclosporine in de Novo Renal Transplant Recipients

Start date: September 2008
Phase: Phase 2
Study type: Interventional

This study will assess safety and efficacy of AEB071 combined with everolimus in a CNI-free (calcineurin inhibitor) regimen in renal transplant recipients.

NCT ID: NCT00820508 Completed - Clinical trials for Lymphoid Malignancies

Safety and Tolerability of CHR-2845 to Treat Haematological Diseases or Lymphoid Malignancies

CHR-2845-001
Start date: December 2008
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether the histone deacetylase inhibitor CHR-2845 is tolerated in patients with haematological diseases and lymphoid malignancies.

NCT ID: NCT00819611 Completed - Clinical trials for Attention Deficit Disorder With Hyperactivity

Working Memory Training in Young ADHD Children

Start date: June 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate whether working memory training improves behavioral symptoms, neurocognitive performance, and neural functioning in young children with ADHD.

NCT ID: NCT00819156 Completed - Prostate Cancer Clinical Trials

Dose Finding Trial With a New Treatment (Degarelix) for Prostate Cancer

Start date: February 2004
Phase: Phase 2
Study type: Interventional

The purpose of the trial was to evaluate the safety and efficacy of degarelix when comparing six different doses. The patients participating in the trial were treated with degarelix every month for a year. During the treatment the patients had to visit the clinic for investigations. Blood samples for testosterone, dihydrotestosterone, luteinizing hormone, follicle stimulating hormone, and Prostate Specific Antigen were taken and analysed throughout the trial.