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NCT ID: NCT01911715 Completed - Healthy Subjects Clinical Trials

A Study to Explore the Routes of Elimination of MDV3100

Start date: April 2011
Phase: Phase 1
Study type: Interventional

A study to investigate the excretion routes of radio-labelled MDV3100.

NCT ID: NCT01911611 Completed - Healthy Volunteer Clinical Trials

A Study of RO6870868 in Healthy Volunteers

Start date: August 2013
Phase: Phase 1
Study type: Interventional

This randomized, double-blind, placebo-controlled study will evaluate the safety, tolerability, pharmacokinetics of RO6870868 in healthy volunteers. Subjects will be randomized to receive single ascending doses of either RO6870868 or placebo, with or without food.

NCT ID: NCT01910987 Completed - Multiple Myeloma Clinical Trials

Study to Evaluate Optimized Retreatment and Prolonged Therapy With Bortezomib

OPTIMRETREAT
Start date: April 2013
Phase: Phase 3
Study type: Interventional

The objective of this study is to describe the effect of optimized retreatment with bortezomib in combination with dexamethasone followed by prolonged therapy with bortezomib, versus standard retreatment with bortezomib in combination with dexamethasone on progression free survival (PFS).

NCT ID: NCT01910415 Completed - Cystic Fibrosis Clinical Trials

Phase 1, QT/QTC Interval Study in Healthy Subjects

Start date: June 2013
Phase: Phase 1
Study type: Interventional

This study is designed to evaluate the effect of multiple doses of lumacaftor in combination with ivacaftor on cardiac repolarization, as detected by QT/QTc interval corrected for heart rate in healthy subjects.

NCT ID: NCT01909349 Completed - Clinical trials for CARDIOVASCULAR DISEASES

Web-based Aftercare Intervention for Cardiac Patients

RENATA
Start date: September 2013
Phase: N/A
Study type: Interventional

Persons undergoing cardiac rehabilitation often have difficulties transferring the learned health behaviors into their daily routine which decreases their health status. Computer-based tailored interventions have been shown to be effective in increasing physical activity as well as fruit and vegetable consumption. The aim of this study is, to support people in transferring these two learned behavior changes and their antecedents into their daily life after cardiac rehabilitation in Germany, the Netherlands and China. The primary goal of the study is to analyze the effectiveness of a rehabilitation aftercare program with regard to the level of physical activity and nutrition.

NCT ID: NCT01908829 Completed - Urologic Diseases Clinical Trials

A Trial Comparing Combination Treatment (Solifenacin Plus Mirabegron) With One Treatment Alone (Solifenacin)

BESIDE
Start date: July 10, 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study was to see if adding a new type of medication recently approved to treat overactive bladder (mirabegron) to an antimuscarinic treatment (solifenacin) would be more effective in controlling incontinence than when using the antimuscarinic treatment alone.

NCT ID: NCT01908465 Completed - Clinical trials for Irritable Bowel Syndrome (IBS)

Peripheral Histamine 1 Receptor Blockade in IBS: Multicenter Trial

Start date: November 2013
Phase: Phase 4
Study type: Interventional

Purpose: To evaluate the efficiency of Irritable Bowel Syndrome (IBS) patients treatment with the H1-receptor antagonist ebastine. Design: Double blind randomized placebo controlled trial. IBS patients receive a 12-weeks treatment with ebastine 20mg once daily or placebo (1:1 randomization).

NCT ID: NCT01908426 Completed - Clinical trials for Hepatocellular Carcinoma

Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib

CELESTIAL
Start date: September 26, 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effect of Cabozantinib (XL184) compared with placebo on overall survival in subjects with advanced hepatocellular carcinoma who have received prior sorafenib.

NCT ID: NCT01908140 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Study of Aclidinium Bromide/Formoterol Fumarate Compared With Salmeterol/Fluticasone Propionate in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Start date: September 2013
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare the efficacy, safety and tolerability of aclidinium bromide/formoterol fumarate and salmeterol/fluticasone propionate in patients with chronic obstructive pulmonary disease (COPD)

NCT ID: NCT01907152 Completed - Clinical trials for Markedly Reduced Food Intake

Increase Protein Intake in Elderly

Start date: September 2013
Phase: N/A
Study type: Interventional

The objective of this study is to investigate the acceptance, intake, and compliance of protein enriched bread and protein enriched yoghurt drinks in elderly patients in two real life settings (short term; hospital, and longer term; rehabilitation home).