Clinical Trials Logo

Filter by:
NCT ID: NCT00257205 Completed - Melanoma Clinical Trials

CP-675,206 Versus Either Dacarbazine Or Temozolomide In Patients Without Prior Therapy

Start date: March 2006
Phase: Phase 3
Study type: Interventional

This is a Phase 3, multi-national, open-label, 2-arm randomized study in patients with surgically incurable metastatic melanoma who have received no prior chemotherapy, or biochemotherapy for the treatment of metastatic disease. The primary objective of this trial is to compare overall survival for patients with advanced melanoma who are randomized to receive CP-675,206 with that of patients who are randomized to receive either dacarbazine or temozolomide (investigator choice)

NCT ID: NCT00256867 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Study In Patients With Type 2 Diabetes Mellitus

Start date: August 18, 2005
Phase: Phase 3
Study type: Interventional

This study evaluates the effect of medicines for type 2 diabetes and lipids control. This study will require about 6 office visits for lab tests and examinations. All study related medicines and medical examinations will be provided at no cost to the subjects.

NCT ID: NCT00256750 Completed - Clinical trials for Kidney Transplantation

Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosuppression (BENEFIT)

BENEFIT
Start date: March 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to learn if Belatacept can provide protection from organ rejection following kidney transplantation while avoiding some of the toxic effects of standard immunosuppressive medications such as kidney damage. Effects on kidney function and patient survival as well as drug safety will also be studied.

NCT ID: NCT00256113 Completed - Depressive Disorder Clinical Trials

An Eight-week Study to Evaluate the Efficacy and Safety of Saredutant in Patients With Depression

Start date: December 2004
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the efficacy and safety of saredutant (or SR48968C) in patients with depression. The primary objective is to evaluate the efficacy of a 100 mg dose of saredutant compared to placebo in patients with depression. The secondary objectives are to evaluate the safety of saredutant, to evaluate the efficacy of saredutant on disability and quality of life in patients with depression, and to evaluate blood levels of saredutant.

NCT ID: NCT00255645 Terminated - Type 2 Diabetes Clinical Trials

G-PLUS (GALLANT, GALLEX and ARMOR - Post Treatment Follow-up Study)

Start date: September 2005
Phase: Phase 3
Study type: Observational

This is a long-term safety follow-up study to assess the post-treatment safety, at 12 and 24 months, in patients with type 2 diabetes after participation in the phaseII/III studies GALLANT, GALLEX and ARMOR. In addition, selected patients, including those with pre-defined laboratory or clinical findings, will have a 12-week post-treatment follow-up visit, including laboratory evaluation and adverse event recording.

NCT ID: NCT00255541 Terminated - Type 2 Diabetes Clinical Trials

GALLANT 4 Tesaglitazar vs. Glibenclamide

Start date: September 2004
Phase: Phase 3
Study type: Interventional

This is a 52-week randomized, double-blind, parallel-group, multi-center, active-controlled (glibenclamide) study of tesaglitazar in patients with type 2 diabetes, not adequately controlled on diet and lifestyle advice alone during the run-in period. The study comprises a 6 week placebo single blind run in period followed by a 52-week double blind treatment period and a 3-week follow-up period. Tesaglitazar and glibenclamide will be titrated to optimal effect or highest tolerable dose during the first 12 weeks.

NCT ID: NCT00255268 Withdrawn - Clinical trials for Metastatic Prostate Cancer

CMAB vs IMAB in Metastatic Prostate Cancer

Start date: August 2004
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy, safety and survival of two treatment regimens: Continuous Intermittent Maximum Androgen Blockade, using goserelin and bicalutamide in patients with prostate cancer. Primary endpoint is time to progression. Fifteen patients will be evaluated. QoL evaluation is also included.

NCT ID: NCT00254891 Terminated - Clinical trials for Carcinoma, Non-Small-Cell Lung

Trial of Paclitaxel/Carboplatin + PF-3512676 vs Paclitaxel/Carboplatin Alone in Patients With Advanced Non-Small Cell Lung Cancer

Start date: November 2005
Phase: Phase 3
Study type: Interventional

To assess the efficacy and safety of PF-3512676 administered in combination with paclitaxel/carboplatin chemotherapy as first-line treatment in patients with locally advanced or metastatic Non-Small-Cell Lung Cancer (NSCLC) and to compare it to the efficacy and safety of paclitaxel

NCT ID: NCT00254046 Completed - HIV Clinical Trials

TMC125-C206: A Phase III Study to Investigate the Efficacy, Tolerability and Safety of TMC125 as Part of an Antiretroviral Regimen, Including TMC114/Ritonavir and an Investigator-selected Optimized Background, in HIV-1 Infected Patients With Limited to no Treatment Options.

Start date: November 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is research with the goal of evaluating the effect of TMC125 (a non-nucleoside reverse transcriptase inhibitor) on slowing down the growth of the HIV virus. The study will also investigate whether this new medication is well tolerated, and to further confirm that the medication is safe to be used.

NCT ID: NCT00253968 Completed - Insomnia Clinical Trials

Efficacy and Safety of Eplivanserin Treatment for Sleep Maintenance Insomnia

GEMS
Start date: November 2005
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess efficacy and safety of eplivanserin in the population of patients complaining of sleep maintenance insomnia. The patients suffering from that condition frequently wake up during the night, their sleep is nonrestorative and they suffer from a significant distress or impairment in their daily activities consecutive to insomnia.