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NCT ID: NCT00328120 Completed - Clinical trials for Advanced Breast Cancer

Faslodex 500mg Multiple Dose Tolerability Study in BC Patients

Start date: April 2004
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to assess the tolerability of 500mg fulvestrant in postmenopausal women with hormone receptor positive, advanced or recurrent breast cancer

NCT ID: NCT00326950 Completed - Cancer Clinical Trials

Phase I Clinical Study of E7389

Start date: June 2006
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to determine the dose limiting toxicity and maximum tolerated dose of E7389 in patients with solid tumors. The secondary objectives are to investigate the pharmacokinetics, safety, estimated recommended dose, and anti-tumor effects (in evaluable cases) of E7389 in patients with solid tumors.

NCT ID: NCT00326768 Completed - Hypertension Clinical Trials

Trial of Telmisartan 80 mg/HCTZ 12.5 mg and Telmisartan 40 mg/HCTZ 12.5 mg in Patients With Hypertension

Start date: May 2006
Phase: Phase 3
Study type: Interventional

The objective of this trial is to assess the safety and efficacy of 52 weeks of open-label treatment with the fixed dose combination of telmisartan 80 mg plus HCTZ 12.5 mg and telmisartan 40 mg plus HCTZ 12.5 mg in patients with essential hypertension.

NCT ID: NCT00325429 Completed - Clinical trials for Diabetes Mellitus, Type 2

Long-Term Safety Study of Vildagliptin in Patients With Type 2 Diabetes

Start date: April 2006
Phase: Phase 3
Study type: Interventional

This study is not being conducted in the United States. Vildagliptin is an oral antidiabetic agent. This 52-week clinical study is designed as an open label, long-term study aimed to evaluate the safety of vildagliptin in patients with type 2 diabetes.

NCT ID: NCT00325390 Completed - Clinical trials for Platelet Aggregation Inhibitors

Efficacy and Safety in Patients With Acute Coronary Syndrome Without ST-Segment Elevation

Start date: July 2004
Phase: Phase 3
Study type: Interventional

To evaluate the efficasy and safety of SR25990C(loading dose:300mg, maintenance dose:75mg/day) in comparison with the standard Japanese treatment(ticlopidine) in patients with acute coronary syndrome without ST-segment elevation and planned for percutaneous coronary intervention(including stenting).

NCT ID: NCT00325117 Completed - Clinical trials for Diabetes Mellitus, Type 2

To Assess the Efficacy and Safety of Vildagliptin as Add-on Therapy to Sulfonylurea in Patients With Type 2 Diabetes Inadequately Controlled With Sulfonylurea Monotherapy

Start date: April 2006
Phase: Phase 3
Study type: Interventional

This study is not being conducted in the United States. Vildagliptin is an oral antidiabetic agent. This 12-week clinical study is designed as a multicenter, randomized, double-blind, parallel-group, placebo-controlled study aimed to evaluate the efficacy and safety of vildagliptin as add-on therapy to a sulfonylurea in patients with type 2 diabetes inadequately controlled with sulfonylurea monotherapy.

NCT ID: NCT00322452 Completed - Clinical trials for Non-Small Cell Lung Cancer

First Line IRESSAâ„¢ Versus Carboplatin/Paclitaxel in Asia

IPASS
Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare gefitinib with carboplatin / paclitaxel doublet chemotherapy given as first line treatment in terms of progression free survival in selected NSCLC patients with the objective of demonstrating non-inferiority.

NCT ID: NCT00321854 Completed - Parkinson Disease Clinical Trials

Study of (Mirapex) Pramipexole for the Early Treatment of Parkinsons Disease (PD)

Start date: May 2006
Phase: Phase 4
Study type: Interventional

This is a double blind, placebo-controlled clinical trial of 15 months duration designed to examine early Mirapex (pramipexole) treatment vs. delayed Mirapex (pramipexole) treatment in patients with new onset Parkinsons disease

NCT ID: NCT00320411 Completed - Neoplasms, Breast Clinical Trials

GW572016 In Patients With ErbB2 Over - Expressing Advanced Or Metastatic Breast Cancer

Start date: November 28, 2005
Phase: Phase 2
Study type: Interventional

This study (EGF104911) is designed to evaluate the efficacy and safety of lapatinib in patients with advanced or metastatic breast cancer. Eligible subjects must have ErbB2 overexpressing tumors and are refractory to treatment with anthracycline, taxanes and trastuzumab containing regimens. The study data obtained from EGF104911 will be combined with the data from EGF100642 and integrated analysis will be carried out in order to enhance the credibility of the study results.

NCT ID: NCT00319917 Completed - Clinical trials for Rheumatoid Arthritis

A Double Blind Placebo Controlled Study to Assess the Efficacy on Joint Damage in RA Patients

Start date: April 2006
Phase: Phase 4
Study type: Interventional

The purpose of the study is to assess the efficacy on joint damage and safety in RA patients treated with DMARDs in a double blind, placebo controlled study.