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NCT ID: NCT02805374 Completed - Healthy Subjects Clinical Trials

A Food Effect Study to Evaluate the Pharmacokinetics of ASP1517

Start date: July 2016
Phase: Phase 1
Study type: Interventional

The objective of this study is to evaluate the effect of food on the pharmacokinetics of a single oral dose of ASP1517 in non-elderly healthy adult male subjects.

NCT ID: NCT02805348 Completed - Clinical trials for Chronic Kidney Disease

Post-marketing Surveillance of Bixalomer in Patients With Pre-dialysis Chronic Kidney Disease

Start date: June 1, 2016
Phase:
Study type: Observational

The objective of this study is to assess the long-term safety and efficacy of bixalomer under post-marketed setting.

NCT ID: NCT02804243 Completed - Rehabilitation Clinical Trials

The Efficacy of Nasal High Flow Oxygen Therapy With Rehabilitation in the Patients With Chronic Respiratory Failure

Start date: June 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the exercise endurance between oxygen therapy with rehabilitation and nasal high flow therapy with rehabilitation for the patients with chronic respiratory failure receiving long-term oxygen therapy.

NCT ID: NCT02803437 Active, not recruiting - Clinical trials for Prostatic Neoplasms, Castration-Resistant

Drug Use Investigation of Xofigo, Castration Resistant Prostate Cancer With Bone Metastases

Start date: July 21, 2016
Phase:
Study type: Observational [Patient Registry]

This study is a Japanese post-marketing surveillance (PMS) which is required by the regulatory authorities. General objective of PMS is to confirm the clinical usefulness, especially the safety profile of a drug under the routine clinical practice.

NCT ID: NCT02802345 Completed - Clinical trials for Idiopathic Pulmonary Fibrosis

Efficacy and Safety of Nintedanib Co-administered With Sildenafil in Idiopathic Pulmonary Fibrosis Patients With Advanced Lung Function Impairment

Start date: June 30, 2016
Phase: Phase 3
Study type: Interventional

To assess efficacy and safety of concomitant treatment with nintedanib and sildenafil in Idiopathic Pulmonary Fibrosis (IPF) patients with advanced lung function impairment.

NCT ID: NCT02801981 Completed - Cholestasis Clinical Trials

Dose-escalation Study of GSK2330672 in Japanese Healthy Male Volunteers

Start date: June 2016
Phase: Phase 1
Study type: Interventional

This study will be the first to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics following single dose of 10 milligrams (mg) to 180 mg of GSK2330672 in Japanese healthy subjects. This is a double-blind, randomized, placebo-controlled, dose-escalating and incomplete block crossover study to be conducted in 16 Japanese healthy subjects. Study will be conducted in four periods; subjects will receive either placebo or GSK2330672 (10 mg, 30 mg, 90 mg or 180 mg based on randomization) in each treatment period. Each period will be separated by washout period (at least 6 days from dosing). Total duration of study for each subject will be approximately 5 weeks from the first dosing to follow up visit.

NCT ID: NCT02801708 Recruiting - Stroke Clinical Trials

Enhanced Detection of Underlying, Covert ATrial Fibrillation Using 7-day Holter Electrocardiogram in Patients With Embolic Stroke of Undetermined Source

EDUCATE-ESUS
Start date: August 2014
Phase: N/A
Study type: Observational

The aim of this study is to determine the diagnostic yield of continuous 7-day Holter ECG for detecting covert paroxysmal atrial fibrillation in patients with recent embolic stroke or transient ischemic attack (TIA) of undetermined cause after completion of a standard clinical work up including an initial 24-hour Holter monitoring.

NCT ID: NCT02801669 Completed - Atrial Fibrillation Clinical Trials

Study of DU-176b Aged 80 Years or Older

Start date: August 5, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of edoxaban in patients with non-valvular NVAF aged 80 years or older who are ineligible for available oral anticoagulation therapy.

NCT ID: NCT02801006 Completed - Astigmatism Clinical Trials

The Clinical Study of Silicone Hydrogel Daily Disposable Stenfilcon A Toric Lens

Start date: April 2016
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the clinical performance of stenfilcon A toric lenses compared with etafilcon A toric lenses for astigmatism. If it is valuable, the clinical performance of stenfilcon A toric lens is also evaluated compared with habitual lenses.

NCT ID: NCT02799602 Completed - Clinical trials for Metastatic Hormone-sensitive Prostate Cancer

Darolutamide in Addition to Standard Androgen Deprivation Therapy and Docetaxel in Metastatic Hormone-Sensitive Prostate Cancer

ARASENS
Start date: November 30, 2016
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the efficacy and safety of BAY1841788 (darolutamide (ODM-201)) in combination with standard androgen deprivation therapy (ADT) and docetaxel in patients with metastatic hormone sensitive prostate cancer.