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NCT ID: NCT02811302 Completed - Clinical trials for Respiratory Depression

PRediction of Opioid-induced Respiratory Depression In Patients Monitored by capnoGraphY

PRODIGY
Start date: April 7, 2017
Phase: N/A
Study type: Interventional

PRODIGY is a prospective, multi-center, post-market, international cohort study. The primary objective of this study is to derive a score to identify subjects at risk to have respiratory depression (RD) episodes in patients undergoing opioid therapy in the hospital ward and monitored by capnography. The score will be derived by using subjects within the derivation cohort and internally validated using subjects within the validation cohort. The primary endpoint used to derive the score will be the occurrence of RD episodes derived by Capnostream 20p device memory data combined with clinical data and validated by an independent Clinical Endpoint Committee (CEC) during the study course.

NCT ID: NCT02810457 Completed - Clinical trials for Carcinoma, Non-Small-Cell Lung

Evaluation of FKB238 and Avastin in Patients With Advanced/Recurrent Non-squamous Non-small Cell Lung Cancer

AVANA
Start date: September 7, 2016
Phase: Phase 3
Study type: Interventional

The purpose of this research study is to compare the effectiveness and safety of FKB238 against Avastin® in men and women with advanced/recurrent non squamous non-small cell lung cancer

NCT ID: NCT02809105 Completed - Clinical trials for Chronic Constipation

A Study of Oral Dosing of ASP0456 in Patients With Chronic Constipation

Start date: June 24, 2016
Phase: Phase 3
Study type: Interventional

The objective of this study is to verify the efficacy and investigate the safety of the study drug when ASP0456 is administered orally for 4 weeks and 52 weeks.

NCT ID: NCT02808429 Terminated - IgA Nephropathy Clinical Trials

Efficacy and Safety of Atacicept in IgA Nephropathy

Start date: January 31, 2017
Phase: Phase 2
Study type: Interventional

This main purpose of this study was to evaluate the safety, tolerability, dose response and efficacy of Atacicept in participants with IgA nephropathy and persistent proteinuria. The study hypothesis was that treatment with Atacicept would reduce proteinuria compared to placebo.

NCT ID: NCT02808403 Completed - Clinical trials for Hypercholesterolemia

Long Term Post Marketing Specified Drug Use Result Survey for Evolocumab in Japan

Start date: June 24, 2016
Phase:
Study type: Observational

The purpose of this post-marketing survey is to obtain real-world information on the safety and effectiveness of evolocumab in Japan.

NCT ID: NCT02808026 Completed - Severe Hypertension Clinical Trials

Study of CS-3150 in Patients With Severe Hypertension

Start date: June 2016
Phase: Phase 3
Study type: Interventional

To examine antihypertensive effect and safety of administration of CS-3150 in patients with severe hypertension (Grade III).

NCT ID: NCT02807987 Completed - Clinical trials for Hypertension With Moderate Renal Impairment

Study of CS-3150 in Combination With ARB or ACE Inhibitor in Hypertensive Patients With Moderate Renal Impairment

Start date: June 2016
Phase: Phase 3
Study type: Interventional

To examine antihypertensive effect and safety of administration of CS-3150 in combination with ARB or ACE inhibitor in hypertensive patients with moderate renal impairment.

NCT ID: NCT02807974 Completed - Hypertension Clinical Trials

Study of CS-3150 in Hypertensive Patients With Type 2 Diabetes and Albuminuria

Start date: June 2016
Phase: Phase 3
Study type: Interventional

To examine antihypertensive effect and safety of administration of CS-3150 in combination with ARB or ACE inhibitor in hypertensive patients with type 2 diabetes and albuminuria.

NCT ID: NCT02807844 Completed - Melanoma Clinical Trials

Phase Ib/II Study of MCS110 in Combination With PDR001 in Patients With Advanced Malignancies

Start date: June 29, 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study of MCS110 with PDR001 was to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and antitumor activity of the combination of MCS110 with PDR001 in adult patients with solid tumors.

NCT ID: NCT02807636 Completed - Clinical trials for Urothelial Carcinoma

Study of Atezolizumab as Monotherapy and in Combination With Platinum-Based Chemotherapy in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma

IMvigor130
Start date: June 30, 2016
Phase: Phase 3
Study type: Interventional

A Phase III, randomised study of atezolizumab alone and in combination with chemotherapy versus chemotherapy alone in participants with untreated advanced urothelial cancer.