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NCT ID: NCT03471299 Completed - Hemodialysis Clinical Trials

Association of Survival in Impact of Ultrafiltration Rates in Hemodialysis Patients

Start date: April 1, 2017
Phase:
Study type: Observational

This study assesses retrospectively the association of mortality on UFR assessments in our study population undergoing HD.

NCT ID: NCT03467152 Completed - Clinical trials for Dementia With Lewy Bodies

Study To Evaluate the Efficacy, Safety and Tolerability of E2027 (Hereinafter Referred to as Irsenontrine) in Participants With Dementia With Lewy Bodies

Start date: May 4, 2018
Phase: Phase 2
Study type: Interventional

This study will be conducted to compare Irsenontrine to placebo on the cognitive endpoint of Montreal Cognitive Assessment (MoCA) and the global clinical endpoint of Clinician's Interview Based Impression of Change Plus (CIBIC-Plus) Caregiver Input in participants with dementia with Lewy bodies after 12 weeks of treatment.

NCT ID: NCT03466814 Completed - Clinical trials for Undifferentiated Arthritis

Study of the Safety of Orencia in Japanese Children and Adolescents With Active Juvenile Arthritis of Unknown Origin

Start date: April 6, 2018
Phase:
Study type: Observational

Observational study of abatacept in the treatment of JIA in Japan.

NCT ID: NCT03466671 Active, not recruiting - Clinical trials for Autism Spectrum Disorder

A Trial of TTA-121 on Autism Spectrum Disorder

Start date: February 27, 2018
Phase: Phase 2
Study type: Interventional

To test efficacy and safety of a novel nasal spray of oxytocin on social deifies in autism spectrum disorder, and To compare effect sizes of different doses

NCT ID: NCT03466411 Active, not recruiting - Crohn's Disease Clinical Trials

A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

GALAXI
Start date: April 13, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 and GALAXI 3) and safety of guselkumab in participants with Crohn's disease.

NCT ID: NCT03465540 Terminated - Multiple Myeloma Clinical Trials

Safety, Tolerability, Pharmacokinetics and Efficacy of AMG 397 in Subjects With Selected Relapsed or Refractory Hematological Malignancies

Start date: August 17, 2018
Phase: Phase 1
Study type: Interventional

Evaluate the safety and tolerability of AMG 397. Estimate the maximum tolerated doses (MTDs) and/or biologically active doses.

NCT ID: NCT03462498 Active, not recruiting - Clinical trials for Coronary Artery Disease

ShorT and OPtimal Duration of Dual AntiPlatelet Therapy-2 Study for the Patients With ACS

STOPDAPT-2 ACS
Start date: April 2, 2018
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the safety of reducing dual antiplatelet therapy (DAPT) duration to 1 month after implantation of the everolimus-eluting cobalt-chromium stent (CoCr-EES) under the setting of acute coronary syndrome (ACS).

NCT ID: NCT03461497 Active, not recruiting - Abdominal Surgery Clinical Trials

Development of a Patient-Reported Outcome Measure to Assess Recovery After Abdominal Surgery

Start date: July 2016
Phase:
Study type: Observational

As surgery enters the era of value-based care, it is advocated that postoperative recovery be measured using patient-reported outcomes (PROs) as they provide a mean to incorporate the patient's perspectives and experiences into research and clinical decision-making. In abdominal surgery, this is currently precluded by the lack of PRO measures specifically developed and validated in the context of postoperative recovery. The core goal of this research project is to develop a PRO measure aimed to assess postoperative recovery from the perspective of patients undergoing abdominal surgery. This project complies with the US Food and Drug Administration (FDA) and International Society for Pharmacoeconomics and Outcomes Research (ISPOR) guidelines for PRO development and will be conducted in three phases: Phase 1: Qualitative interviews with patients to develop a conceptual framework and generate relevant items. Phase 2: Use of Rasch Analysis for item-reduction and scale formation. Phase 3: Further assessment of measurement properties based on traditional psychometric methods.

NCT ID: NCT03461146 Completed - Clinical trials for Anemia; Hemodialysis Dependent Chronic Kidney Disease

Efficacy and Safety Study to Evaluate MT-6548 in Hemodialysis Subjects Not Receiving ESAs With Anemia Associated With Chronic Kidney Disease in Japan

Start date: March 5, 2018
Phase: Phase 3
Study type: Interventional

For hemodialysis subjects not receiving ESAs with anemia associated with chronic kidney disease, evaluate Hb correction and maintenance effect and safety of MT-6548.

NCT ID: NCT03461042 Completed - Chronic Insomnia Clinical Trials

The Study of Combination Use of Melatonin Receptor Agonist for Dose Reduction or Interruptions of Benzodiazepine (BZD) and Non-BZD Hypnotics on Chronic Insomnia

BRED
Start date: February 6, 2018
Phase: Phase 4
Study type: Interventional

To investigate effects on combination use of Ramelteon in the dose reduction or interruption process of (non-)BZD hypnotics during the dose reduction or interruption algorithm.