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NCT ID: NCT02039505 Completed - Ulcerative Colitis Clinical Trials

Phase III Study of MLN0002 (300 mg) in the Treatment of Ulcerative Colitis

Start date: February 4, 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate efficacy, safety and pharmacokinetics of the vedolizumab (MLN0002) induction and maintenance therapy in Japanese participants with moderate or severe ulcerative colitis (UC).

NCT ID: NCT02039063 Completed - Crohn's Disease Clinical Trials

A Phase 1/2 Study of Repeated Intravenous E6011 Administration in Japanese Subjects With Crohn's Disease

Start date: April 5, 2014
Phase: Phase 1/Phase 2
Study type: Interventional

This study is a multicenter, open-label, uncontrolled, multiple ascending dose (MAD) study to evaluate mainly the safety and tolerability of 12-week repeated intravenous administration of E6011. A total of 24 subjects will enroll into four cohorts. Six subjects per cohort will receive repeated intravenous administration of E6011.

NCT ID: NCT02038920 Completed - Crohn's Disease Clinical Trials

Phase III Study of MLN0002 (300 mg) in Treatment of Crohn's Disease

Start date: January 28, 2014
Phase: Phase 3
Study type: Interventional

This study is a phase 3, multicenter, randomized, double-blinded, placebo-controlled, parallel-group study to examine the efficacy, safety, and pharmacokinetics of vedolizumab (MLN0002) in induction and maintenance therapy in Japanese participants with moderately or severely active Crohn's disease.

NCT ID: NCT02038868 Completed - Clinical trials for Benign Prostate Hyperplasia

A Study to Evaluate the Efficacy and Safety of ASP4901 in Patients With Benign Prostate Hyperplasia

Start date: July 22, 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the efficacy of ASP4901 with placebo in patients with benign prostatic hyperplasia. The safety and tolerability of ASP4901 will also be evaluated.

NCT ID: NCT02038777 Completed - Clinical trials for Acute Myeloid Leukemia

A Study Of PF-04449913 In Japanese Patients With Select Hematologic Malignancies

Start date: March 25, 2014
Phase: Phase 1
Study type: Interventional

This is an open-label, multi-center, Phase 1 study of PF-04449913 in Japanese patients. PF-04449913 will be administered orally as a single agent in patients with select advanced hematologic malignancies, or in combination with LDAC [Low-Dose Ara-C] or cytarabine and daunorubicin in previously untreated patients with AML [Acute Myeloid Leukemia] or high-risk MDS [Myelodysplastic Syndrome], or in combination with azacitidine in previously untreated patients with AML.

NCT ID: NCT02038673 Completed - Solid Tumors Clinical Trials

An Open-label Phase I Study of Orally Available Novel Small-molecule Fibroblast Growth Factor Receptors (FGFR) 1,2,3 and 4 Inhibitor, ASP5878 at Single and Multiple Doses in Patients With Solid Tumors

Start date: November 5, 2013
Phase: Phase 1
Study type: Interventional

The objectives of this study are to determine the tolerability, safety, pharmacokinetics (PK), pharmacodynamics (PD), and efficacy of oral ASP5878 in participants with solid tumors.

NCT ID: NCT02037776 Completed - Clinical trials for Functional Dyspepsia

The Efficacy and Safety Study of Rikkunshito in Patients With Functional Dyspepsia

Start date: April 3, 2014
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of Rikkunshito compared to placebo in Japanese subjects with Functional Dyspepsia (FD).

NCT ID: NCT02037477 Completed - Healthy Clinical Trials

Phase 3 Study to Evaluate the Acid-Inhibitory Effect of Multiple Oral Doses of TAK-438

Start date: January 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the acid-inhibitory effect of multiple oral doses of TAK-438 and the relative effect of TAK-438 versus two controls (esomeprazole and rabeprazole sodium) in healthy Japanese adult male participants with the CYP2C19 EM genotype.

NCT ID: NCT02036580 Completed - Clinical trials for Idiopathic Pulmonary Fibrosis

D2212C00002 J-Phase II Study

Start date: January 2014
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the safety and tolerability of multiple-doses of tralokinumab in Japanese patients with Idiopathic Pulmonary Fibrosis.

NCT ID: NCT02036047 Completed - Clinical trials for Postpolypectomy Bleeding

The Effectiveness of an Exclusive Cold Snare Polypectomy Snare for the Removal of Diminutive Colorectal Polyps

Start date: January 2014
Phase: N/A
Study type: Interventional

The use of an exclusive cold polypectomy snare enables a clean cut of diminutive colorectal polyps, resulting in an increase in the complete resection rate and a decrease in the adverse events.