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NCT ID: NCT04844918 Completed - Obesity Clinical Trials

A Study of Tirzepatide (LY3298176) in Participants With Obesity Disease

SURMOUNT-J
Start date: May 10, 2021
Phase: Phase 3
Study type: Interventional

The main purpose of this study is to learn more about tirzepatide in participants with obesity disease. The study will also measure how Tirzepatide affects body weight with a low-calorie diet and increased physical activity. The study will last around 72 Weeks.

NCT ID: NCT04842643 Completed - Clinical trials for Primary Immunodeficiency Disease

An Extension Study of TAK-664 for Japanese People With Primary Immunodeficiency Disease

Start date: April 27, 2021
Phase: Phase 3
Study type: Interventional

This study is an extension study for participants with primary immunodeficiency disorders who were previously treated with IGSC, 20% in the TAK-664-3001 study. They must have completed that study or be about to complete it before joining this study. Participants will continue treatment with IGCS, 20% in this study. The main aim of this study is to check for side effects from long-term treatment with IGSC, 20% . This medicine is not yet licensed in Japan, so participants will be treated with IGSC, 20% until it becomes commercially available.

NCT ID: NCT04842604 Completed - Clinical trials for Acute Myeloid Leukemia

Continuation Study of B1371019(NCT03416179) and B1371012(NCT02367456) Evaluating Azacitidine With Or Without Glasdegib In Patients With Previously Untreated AML, MDS or CMML

Start date: May 17, 2021
Phase: Phase 3
Study type: Interventional

An open-label study available to all eligible participants from Study B1371019 and participants originating from Study B1371012 continuing on study intervention with azacitidine with or without glasdegib.

NCT ID: NCT04840914 Completed - Clinical trials for Chronic Heart Failure With Reduced Ejection Fraction

A Study of LY3461767 in Participants With Chronic Heart Failure With Reduced Ejection Fraction

Start date: June 1, 2021
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to determine the tolerability and safety of LY3461767 with any side effects that might be associated with it. Study drug will be provided in a continuous subcutaneous infusion lasting 24 hours to 96 hours, depending on the cohort. Blood tests will be performed to check concentrations of LY3461767 in the bloodstream and how long it takes the body to get rid of it in participants with chronic heart failure with reduced ejection fraction (HFrEF). The study will last up to 3 months and may include 5 visits.

NCT ID: NCT04838743 Completed - Clinical trials for Diabetes Mellitus, Type 2

GOAL: A Research Study Looking at Long Term Blood Sugar Control in People With Type 2 Diabetes Treated With Xultophy® in Local Clinical Practice in Japan.

GOAL
Start date: April 23, 2021
Phase:
Study type: Observational

The purpose of this study is to collect information on how Xultophy® works with other oral anti diabetic medication in patients with type 2 diabetes. Participants will get Xultophy® as prescribed by the study doctor. The study will last for about 26 weeks. Participants will be asked questions about health and diabetes treatment and lab tests as part of normal doctor's appointment.

NCT ID: NCT04833855 Completed - Clinical trials for Chronic Spontaneous Urticaria

Study to Evaluate Tezepelumab in Adults With Chronic Spontaneous Urticaria

INCEPTION
Start date: April 15, 2021
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to evaluate the effect of tezepelumab on improvement in the Urticaria Activity Score over 7 days (UAS7).

NCT ID: NCT04828772 Completed - COVID-19 Clinical Trials

A Study of Anticoagulation Treatment Patterns and Outcomes of Participants Hospitalized With Coronavirus Disease 2019 (COVID-19) in Japan

Start date: August 17, 2020
Phase:
Study type: Observational

The purpose of this study is to describe demographic and clinical characteristics of participants who are hospitalized due to coronavirus 2019 (COVID-19), treatment use for COVID-19 and COVID-19 symptoms, and composite outcomes of COVID-19. This study will also compare composite outcomes between COVID-19 participants treated with and without anticoagulant therapy during follow-up period.

NCT ID: NCT04826536 Completed - Psoriasis Clinical Trials

A Study of Treatment Patterns and Clinical Outcomes of Psoriasis in Japan

Start date: June 25, 2021
Phase:
Study type: Observational

The purpose of this study is to understand current real-world treatment patterns and clinical outcomes, reasons for switching treatment, and participant characteristics using each systemic psoriasis treatment in Japan.

NCT ID: NCT04825431 Completed - Clinical trials for Healthy Male Subjects

Mass Balance Study of [14C] TAS-205 in Healthy Volunteers

Start date: March 22, 2021
Phase: Phase 1
Study type: Interventional

To evaluate the pharmacokinetics, mass balance recovery, metabolite profile and metabolite identification of [14C]TAS-205 following oral single doses.

NCT ID: NCT04823611 Completed - Dyslipidemia Clinical Trials

A Study of AZD8233 in Participants With Dyslipidemia.

HAYATE
Start date: January 20, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

A Phase 1 and 2 Study of AZD8233 in Participants with Dyslipidemia and this study consists of Part A , Part B and Part C. Part A is designed as a randomized, single-blind (blinding of participants and sites), placebo-controlled, multiple dose, phase 1 study. Part B is designed as a randomized, double-blind, placebo-controlled, dose-ranging, phase 2 study. Part C is designed as a randomized , single-blind (blinding of participants and sites), placebo-controlled, multiple dose, phase 1 study.