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NCT ID: NCT02337725 Completed - Parkinson's Disease Clinical Trials

A Phase 3 Study of TVP-1012 (1 mg) in Early Parkinson's Disease Patients

Start date: February 7, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of TVP-1012 (1 mg/day) administered to Japanese patients with early Parkinson's disease.

NCT ID: NCT02337569 Completed - Zinc Deficiency Clinical Trials

A Randomized, Double-Blind, Placebo Controlled Study of NPC-02 in Patients With Zinc Deficiency

Start date: January 2015
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate efficacy and safety of NPC-02 in patients with Zinc Deficiency.

NCT ID: NCT02335658 Completed - Schizophrenia Clinical Trials

Long-term Study of DSP-5423P in Patients With Schizophrenia

Start date: December 2014
Phase: Phase 3
Study type: Interventional

The study evaluates the long term safety of DSP-5423P in patients with schizophrenia.

NCT ID: NCT02335346 Completed - Clinical trials for Osteoarthritis of the Knee

An Extension Study of Duloxetine in Osteoarthritis and Knee Pain (Extension of F1J-JE-HMGX, NCT02248480)

Start date: January 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of duloxetine in participants with osteoarthritis and knee pain. The study will last for 1 year.

NCT ID: NCT02334891 Completed - Clinical trials for Congestive Heart Failure

Kyoto Congestive Heart Failure Study

KCHF
Start date: October 2014
Phase:
Study type: Observational [Patient Registry]

The purpose of this study is to investigate the patient characteristics, selection of treatment, and factors associated with clinical outcomes in Japanese patients with acutely decompensated congestive heart failure.

NCT ID: NCT02334787 Completed - Atopic Dermatitis Clinical Trials

A Phase 1 Trial of OPA-15406 Ointment in Healthy Adult Male Subjects

Start date: January 2015
Phase: Phase 1
Study type: Interventional

To assess the safety (especially skin findings) and pharmacokinetics by applying 0.3%, 1%, or 3% formulation of 5g OPA-15406 ointment to a 1000 cm2 area as a single-dose and as a multiple-dose twice daily for 2 weeks in Japanese healthy adult male subjects.

NCT ID: NCT02333370 Completed - Clinical trials for Hormone Receptor Positive, HER2-negative, Advanced Breast Cancer

A Phase Ib Dose Escalation Study of the Combination of LEE011 With Letrozole and Dose Expansion of LEE011 With Hormonal Therapy for the Treatment of Pre-(With Goserelin) and Postmenopausal Women With Hormone Receptor Positive, HER2-negative, Advanced Breast Cancer

Start date: February 4, 2015
Phase: Phase 1
Study type: Interventional

The purpose of the Phase Ib is to: 1. determine the recommended dose of LEE011 in combination with a standard dose of letrozole as well as to provide additional safety and anti-tumor activity data in Asian non-Japanese patients 2. determine the recommended dose of LEE011 in combination with a standard dose of letrozole as well as to provide additional safety and activity data in Japanese patients 3. evaluate the safety and anti-tumor activity of LEE011 at the RP2D established in the dose escalation part in combination with a standard dose of letrozole, fulvestrant or tamoxifen plus goserelin in Japanese patients.

NCT ID: NCT02333331 Completed - Sarcopenia Clinical Trials

Dose Range Finding Study of Bimagrumab in Sarcopenia

Start date: December 9, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study was to determine the efficacy of repeat dosing with multiple dose levels of bimagrumab on patient physical function, skeletal muscle mass and strength in older adults with sarcopenia. In addition, this study generated data on the safety, tolerability, and pharmacokinetics of bimagrumab in older adults with sarcopenia.

NCT ID: NCT02332824 Completed - Clinical trials for Type 2 Diabetes Mellitus and Microalbuminuria

A Phase 2 Dose-finding Study of TAK-272 in Participants With Type 2 Diabetes Mellitus and Microalbuminuria

Start date: October 16, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to test the efficacy and safety on daily oral doses of TAK-272 5 mg, 20 mg, 40 mg and 80 mg in patients with type 2 diabetes mellitus and microalbuminuria by randomized, double-blind, placebo-controlled, parallel-group comparison in order to determine the clinical dose of TAK-272.

NCT ID: NCT02331680 Completed - Clinical trials for Chronic Renal Failure

A Trial to Investigate the Efficacy and Safety of Orally Administered Tolvaptan (OPC-41061) in Patients With Chronic Renal Failure Undergoing Hemodialysis or Hemodiafiltration

Start date: December 2014
Phase: Phase 2
Study type: Interventional

This is a study to investigate the efficacy and safety of OPC-41061 by 24-week oral administration of OPC-41061 at 15-mg or 30-mg or placebo in patients with chronic renal failure who are undergoing hemodialysis or hemodiafiltration and who have daily urine volume of at least 500 mL/day.