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NCT ID: NCT02343458 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD

Start date: March 30, 2015
Phase: Phase 3
Study type: Interventional

A chronic dosing (24 weeks) study to assess the efficacy and safety GFF MDI; PT003), FF MDI; PT005, and GP MDI; PT001) in subjects with moderate to very severe COPD, compared with placebo.

NCT ID: NCT02342665 Completed - Clinical trials for Lymphoma Non-Hodgkin

Japanese Phase Ib/II Copanlisib in Relapsed, Indolent B-cell NHL

Start date: April 21, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

The primary objective of this study is to assess the safety profile of copanlisib at the recommended dose (primary endpoint). The recommended dose of copanlisib for Japanese patients will be determined in the dose escalation/safety evaluation part.

NCT ID: NCT02342184 Completed - Clinical trials for Guillain-Barré Syndrome

Efficacy and Safety Study of GB-0998 for Guillain-Barré Syndrome

Start date: August 2014
Phase: Phase 3
Study type: Interventional

This study will carry out to assess the efficacy of GB-0998 (intravenous immunoglobulin;400mg/kg/day for five days) in the treatment of the Guillain-Barré Syndrome based on the changes in Hughes Functional Grade (FG) as primary endpoint, and in addition, to assess the safety of GB-0998.

NCT ID: NCT02341456 Completed - Clinical trials for Advanced Solid Tumours

Phase Ib Study AZD1775 in Combination With Carboplatin and Paclitaxel in Adult Asian Patients With Solid Tumours

Start date: January 16, 2015
Phase: Phase 1
Study type: Interventional

This is a phase Ib, open-label, multicentre study of AZD1775 administered orally in monotherapy and in combination with carboplatin and paclitaxel to Asian patients with advanced solid tumours.

NCT ID: NCT02340975 Completed - Clinical trials for Gastric or Gastroesophageal Junction Adenocarcinoma

A Phase 1b/2 Study of MEDI4736 With Tremelimumab, MEDI4736 or Tremelimumab Monotherapy in Gastric or GEJ Adenocarcinoma

Start date: March 31, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

This is a randomized, multicenter, open-label, dose-exploration and dose-expansion study to evaluate the safety, tolerability, antitumor activity, PK, pharmacodynamics, and immunogenicity of MEDI4736 in combination with tremelimumab, MEDI4736 monotherapy or tremelimumab monotherapy in participants with metastatic or recurrent gastric or gastroesophageal junction adenocarcinoma.

NCT ID: NCT02340819 Completed - Clinical trials for Short Bowel Syndrome

Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Teduglutide in Japanese Subjects With PN-dependent Short Bowel Syndrome (SBS)

Start date: December 18, 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of an investigational treatment (teduglutide) in Japanese patients with PN-dependent SBS. This study will also look at how teduglutide moves through the body (pharmacokinetics).

NCT ID: NCT02337946 Completed - Clinical trials for Colorectal Carcinoma

Safety and Efficacy Study of mFOLFOX6 + Panitumumab Combination Therapy and 5-FU/LV + Panitumumab Combination Therapy in Participants With Chemotherapy-naïve Unresectable Advanced Recurrent Colorectal Carcinoma

SAPPHIRE
Start date: October 16, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to exploratorily examine efficacy and safety in the participants with chemotherapy-naïve unresectable, advanced/recurrent colorectal carcinoma of Kirsten rat sarcoma-2 virus (KRAS) wild-type who have been treated with 6 cycles (2 weeks/cycle) of first-line mFOLFOX6 + panitumumab combination therapy and then assigned to two groups i.e., a group receiving 5-FU/LV + panitumumab combination therapy and a group receiving mFOLFOX6 + panitumumab combination therapy.

NCT ID: NCT02337764 Completed - Parkinson's Disease Clinical Trials

A Long-term, Phase 3 Study of TVP-1012 (1 mg) in Levodopa Treated Parkinson's Disease Participants

Start date: February 3, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate long-term safety of TVP-1012 (1 mg/day) with levodopa in Japanese participants with Parkinson's disease.

NCT ID: NCT02337751 Completed - Parkinson's Disease Clinical Trials

A Phase 3, Long-term, Extension Study of TVP-1012 (1 mg) in Early Parkinson's Disease Participants

Start date: July 10, 2015
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the long-term safety of TVP-1012 (1 mg/day) in Japanese participants with early Parkinson's disease.

NCT ID: NCT02337738 Completed - Parkinson's Disease Clinical Trials

A Phase 2/3 Study of TVP-1012 at 0.5 mg or 1 mg in Levodopa Treated Parkinson's Disease Participants

Start date: January 27, 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of TVP-1012 (0.5 mg or 1 mg/day) as an add-on to levodopa in Japanese participants with Parkinson's disease with wearing-off phenomenon.