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NCT ID: NCT06257199 Completed - Healthy Patients Clinical Trials

Real-time Measurement of Intra-canal Temperature in Vivo

Start date: May 29, 2023
Phase:
Study type: Observational [Patient Registry]

Included patients will be attending the dental clinics for a root canal treatment. After explaining the procedure and obtaining their consent, the intracanal temperature of the treated tooth will be measured after irrigation with normal saline at 2 different temperatures: 22- and 45-degree Celsius. The intraoral temperature will be recorded using a thermocouple probe inserted inside the canal at the mid-root level. Intraoral temperature will be recorded at the same time using another probe attached to the lingual mucosa. A video will be recorded for the temperature changes over 180 seconds duration starting from the time of placing the irrigation solution into the canal.

NCT ID: NCT06241638 Completed - Diabetes Mellitus Clinical Trials

Improving HbA1c Levels by Methylcobalamin Vitamin in Diabetic Volunteers

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

The current study was conducted to evaluate the prognostic implications of vitamin B12 admission on BMI and HbA1c levels in type 2 diabetic patients treated with Dapagliflozin as a routine medication.

NCT ID: NCT06199869 Recruiting - Clinical trials for Cardiovascular Risk Factors

Cardiovascular Patients With no Standard Modifiable Risk Factors

SMuRF-less-ME1
Start date: January 22, 2024
Phase:
Study type: Observational

A growing number of patients develop atherosclerotic cardiovascular disease (ASCVD) despite the absence of standard modifiable risk factors (SMuRF-less). There is scarcity of studies that address this issue in the Middle Eastern population.

NCT ID: NCT06180070 Completed - Migraine Clinical Trials

Bioequivalence Study to Compare Ibuprofen/ Paracetamol Tablets (200mg Ibuprofen/ 500mg Paracetamol) Versus Nuromol® Tablets (200mg Ibuprofen/ 500mg Paracetamol)

Start date: August 29, 2023
Phase: Phase 1
Study type: Interventional

Randomized, two-way, two-period, single oral dose, open-label, crossover, bioequivalence study to compare Ibuprofen/ Paracetamol tablets (200mg Ibuprofen/ 500mg Paracetamol) versus Nuromol® tablets (200mg Ibuprofen/ 500mg Paracetamol) in healthy subjects under fasting condition.

NCT ID: NCT06180057 Completed - Clinical trials for Cerebrotendinous Xanthomatoses

Bioequivalence Study to Compare Chenodeoxycholic Acid Capsules (250mg Chenodeoxycholic Acid) Versus Chenodeoxycholic Acid Leadiant 250 mg Hard Capsules (250mg Chenodeoxycholic Acid)

Start date: June 12, 2022
Phase: Phase 1
Study type: Interventional

Randomized, two-way, two-period, single oral dose, open-label, crossover, bioequivalence study to compare Chenodeoxycholic acid capsules (250mg chenodeoxycholic acid) [dose: 1 x 02 capsules] versus Chenodeoxycholic acid leadiant 250 mg hard capsules (250mg chenodeoxycholic acid) [dose: 1 x 02 capsules] in healthy subjects under fasting conditions.

NCT ID: NCT06144034 Completed - Epilepsy Clinical Trials

Air Polishing Effect on Biological, Clinical and Patient-reported Experience Among Epileptic and Non-epileptic Children

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

In epileptic and non Epileptic children, the full dentition of each patient was split into four quadrants, starting from the upper right quadrant (1) and moving clockwise until the lower right quadrant (4). Bundled into two groups: quadrant (1+3) vs. (2+4). After randomization, each of these pairs of quadrants had the same treatment modality; test quadrants received treatment with airflow to remove soft biofilm, and ultrasonic scaler for areas with calculus deposits, and control quadrants were treated with conventional rubber cup polishing to remove soft biofilm and ultrasonic scaler for calculus deposits.

NCT ID: NCT06103188 Completed - Anxiety Clinical Trials

Comparing the Effect of Melatonin, Diazepam, and Placebo on Decreasing the Level of Anxiety Preoperatively

Start date: October 2, 2023
Phase: Phase 3
Study type: Interventional

The goal of this clinical trial is to compare the effect of melatonin, diazepam, and placebo on the level of anxiety in patients undergoing surgery. The main question it aims to answer is: • Is melatonin effective in reducing the anxiety of patients undergoing surgery? Participants will be asked to answer a questionnaire then they will receive either melatonin, diazepam, or placebo, and then after an hour, they will answer the same questionnaire again. Researchers will compare melatonin, diazepam, and placebo to see if melatonin is as effective in reducing the level of anxiety as diazepam in patients undergoing surgery.

NCT ID: NCT06103058 Recruiting - Fibromyalgia Clinical Trials

The Prevalence of Fibromyalgia in Adults at Al-Karak Jordan a Cross-sectional Study

Start date: May 12, 2023
Phase:
Study type: Observational [Patient Registry]

Fibromyalgia is a chronic and intricate musculoskeletal disorder characterized by widespread pain, fatigue, and tenderness in specific anatomical regions. Although its prevalence varies among populations, understanding the prevalence in different geographical areas is crucial for healthcare planning. This cross-sectional study aims to determine the prevalence of fibromyalgia in adults residing in Al-Karak, Jordan. The city's unique demographic and environmental characteristics may influence the occurrence of fibromyalgia among its adult population. The study aims to address gaps in knowledge, provide localized insights, and shed light on fibromyalgia's burden on the community's health. Accurate prevalence data aids healthcare planning and resource allocation.

NCT ID: NCT06088979 Recruiting - Thyroid Eye Disease Clinical Trials

A Study to Investigate Efficacy and Safety of TOUR006 in Participants 18 to 75 Years of Age With Thyroid Eye Disease

spiriTED
Start date: February 19, 2024
Phase: Phase 2
Study type: Interventional

Phase 2b trial of TOUR006 in Thyroid Eye Disease (TED) to evaluate 20mg and 50mg doses against placebo given by a subcutaneous injection every eight weeks to TED patients who are in the active inflammatory phase of disease.

NCT ID: NCT06077682 Recruiting - Refractive Errors Clinical Trials

Cycloplegic Refraction in Pediatric Patients With Esotropia

Start date: September 1, 2023
Phase: Phase 4
Study type: Interventional

The primary outcome of this study is to compare cyclopentolate 1% and tropicamide 1% for cycloplegic refractions in pediatric populations with esotropia. This will be a prospective double-blinded randomized clinical trial (RCT), multi-center, with randomized sequencing of cycloplegic agent; each patient received one agent at one visit, and the other agent in the next visit (2 different visits ≥ 1 week apart) within 3 months.