Clinical Trials Logo

Filter by:
NCT ID: NCT02965664 Completed - Presbyopia Clinical Trials

Safety, Tolerability and Efficacy of PresbiDrops (CSF-1) in Presbyopic Subjects

Start date: December 2016
Phase: Phase 2
Study type: Interventional

A study to Establish Safety, Tolerability, and Efficacy of PresbiDrops (CSF-1) in Presbyopic Subjects.

NCT ID: NCT02965196 Not yet recruiting - Low Back Pain Clinical Trials

Dexamethasone Therapy for Low Back Pain

Start date: December 2016
Phase: N/A
Study type: Interventional

The study will evaluate the efficacy of IV Dexamethasone in treatment low back pain as an adjunct to analgesics.

NCT ID: NCT02964338 Terminated - Clinical trials for Chronic Cluster Headache

A Study Comparing the Efficacy and Safety of Fremanezumab (TEV-48125) for the Prevention of Chronic Cluster Headache (CCH)

Start date: January 17, 2017
Phase: Phase 3
Study type: Interventional

The purpose of the current study is to evaluate the efficacy and safety of Fremanezumab (TEV-48125), in the prevention of CCH in adult participants.

NCT ID: NCT02964247 Completed - Clinical trials for Diabetes Mellitus, Type 2

LIRA-ADD2SGLT2i - Liraglutide Versus Placebo as add-on to SGLT2 Inhibitors.

Start date: March 3, 2017
Phase: Phase 3
Study type: Interventional

The trial is conducted in Asia, Europe, North America and South America. The aim of the study is to compare the effect of liraglutide 1.8 mg/day versus placebo as add-on to an SGLT2 inhibitor with or without metformin on glycaemic control in subjects with type 2 diabetes mellitus.

NCT ID: NCT02963922 Completed - Obesity Clinical Trials

Effect and Safety of Liraglutide 3.0 mg in Subjects With Overweight or Obesity and Type 2 Diabetes Mellitus Treated With Basal Insulin

SCALEā„¢ Insulin
Start date: February 6, 2017
Phase: Phase 3
Study type: Interventional

This trial is conducted globally. The aim of this trial is to investigate effect and safety of liraglutide 3.0 mg in subjects with overweight or obesity and type 2 diabetes mellitus treated with basal insulin.

NCT ID: NCT02962921 Completed - Diabetes Mellitus Clinical Trials

Insulin Effects on Cardiac Function in Patients With Diabetes Mellitus

Start date: February 2003
Phase: Phase 4
Study type: Interventional

Our investigation studies the role of acute insulin administration on the diabetic heart, its corresponding effective blood-insulin level and the time-course applicability of insulin in a routine clinical setting. A case series of six male (48.1 ± 4.9 y/o) patients with controlled diabetes (HbA1c of 6.6 ± 0.3%, disease duration of 14.4 ± 6.7 yr). Each subject was evaluated for glucose homeostatic, hemodynamic and echocardiographic systolic and diastolic parameters at baseline and following two successive insulin-load steps of a euglycemic hyperinsulinemic clamp study, each 2 h in duration. Results are presented as a mean ± SEM and analysed using the student's t-test.

NCT ID: NCT02962895 Completed - Clinical trials for Primary Sjogren Syndrome

Safety and Efficacy of VAY736 in Patients With Primary Sjogren's Syndrome (pSS)

Start date: June 27, 2017
Phase: Phase 2
Study type: Interventional

This study will determine the dose-response relationship of VAY736 for key efficacy and safety parameters

NCT ID: NCT02962011 Completed - Cesarean Section Clinical Trials

Trial Comparing Barbed and Non-barbed Suture for Uterine Incision Closure at Cesarean Section

barbed
Start date: August 1, 2016
Phase: Phase 3
Study type: Interventional

This was an unblinded randomized controlled trial. Women were randomized to uterine closure with the knotless barbed suture (Stratafix PDS, Ethicon) or Vicryl (Ethicon) at the time of elective cesarean. The primary outcome was closure time of the uterine incision. Also measured were blood loss during incision closure and the use of additional hemostatic sutures. Informed consent was obtained

NCT ID: NCT02961218 Completed - Sickle Cell Anemia Clinical Trials

Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia

Start date: April 5, 2017
Phase: Phase 2
Study type: Interventional

The study assesses the efficacy, safety and tolerability of ACZ885 (canakinumab) in pediatric and young adult patients with sickle cell anemia (SCA).

NCT ID: NCT02960347 Completed - Ohtahara Syndrome Clinical Trials

Examining the Efficacy of tDCS in the Attenuation of Epileptic Paroxysmal Discharges and Clinical Seizures

Start date: February 2016
Phase: N/A
Study type: Interventional

The current study examined the feasibility of High-Definition tDCS (HD-tDCS) in reducing epileptiform activity in a 30-month-old child suffering from early onset epileptic encephalopathy. HD-tDCS was administered over 10 intervention days spanning two weeks including pre- and post-intervention video-electroencephalography (EEG) monitoring.