Clinical Trials Logo

Filter by:
NCT ID: NCT02973061 Recruiting - Clinical trials for Growth Hormone Deficiency

The Impact of the Use of Recombinant Human Growth Hormone on ADHD Characteristics in Children and Adolescents

Start date: January 2015
Phase:
Study type: Observational

Analysis of the short-and long-term impact of recombinant growth hormone on attention deficit and hyperactivity charachteristics in children and adolescents. This will be examined in children prior to GH therapy and 3, 6 and 12 months during treatment, by filling validated questionnaires (Vanderbilt rating scales) evaluating ADHD. Data will be compared to healthy control group.

NCT ID: NCT02972840 Active, not recruiting - Clinical trials for Lymphoma, Mantle Cell

A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL

Start date: April 5, 2017
Phase: Phase 3
Study type: Interventional

This study is evaluating the efficacy of acalabrutinib in combination with bendamustine and rituximab (BR) compared with placebo plus BR in subjects with previously untreated mantle cell lymphoma.

NCT ID: NCT02972749 Completed - Clinical trials for Intraocular Pressure

Modifiable Factors and Glaucoma - RCT

Start date: November 2016
Phase: N/A
Study type: Interventional

There is growing awareness that environmental factors, behaviors and diet are intimately related to patient health and may play a role in the pathogenesis and progression of glaucoma. Evidence from recent years has shown that some behaviors and environmental factors can affect the intraocular pressure, the primary risk factor for glaucoma. This study aims to investigate whether simple and common lifestyle inteventions such as sleeping with a head elevation, a high fiber diet, moderate aerobic exercise and moderation in caffeine intake could affect intraocular pressure and other outcomes.

NCT ID: NCT02972112 Not yet recruiting - Specific Phobia Clinical Trials

Ultrashort Cognitive Behavioral Intervention for Tokophobia- A Prospective Randomized Single Blinded Controlled Trial

Start date: November 2016
Phase: N/A
Study type: Interventional

Women in their 3rd trimester, represent a unique segment of the tokophobic population. In these cases help is needed within a very short and limited period of time. To date, no specific treatment targets this population in order to ameliorate the anxiety and to provide these women and their newborns with better obstetric and psychiatric outcomes. The present study investigates an accessible individual two session intervention conducted by midwives skilled in CBT (cognitive behavioral therapy) . This intervention is designed to enable stronger emotional regulation and increase of their capacity to accept unexpected changes during labor and feelings of control. The investigators expect this psychological adjustment to lead to a better course of delivery, less interventions including caesarian sections, and subjective birth experience.

NCT ID: NCT02971592 Recruiting - Clinical trials for Back Pain Lower Back Chronic

Estimation of Therapeutic Effect of MDcure on Patients With Chronic Lower Back Pain

E_MDcure_LBP
Start date: January 2017
Phase: Phase 4
Study type: Interventional

This study will assess the therapeutic effect of MDcure® device. MDcure® is an FDA Class 1 listed medical device, produced to ISO-13485 standards, that delivers extremely low intensity (nano Tesla; 10-9) and low frequencies (1-100 Hertz) electromagnetic fields (EMF) intended to reduce muscular aches and pains particularly of the lower back. assessing the reduction of lower back pain. Half of participants will receive the MDcure device, while the other half will receive a mock device.

NCT ID: NCT02970318 Active, not recruiting - Clinical trials for Chronic Lymphocytic Leukemia

A Study of Acalabrutinib vs Investigator's Choice of Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL

Start date: February 2, 2017
Phase: Phase 3
Study type: Interventional

This study is designed to evaluate the efficacy of acalabrutinib compared with rituximab in combination with idelalisib or bendamustine in previously treated subjects with chronic lymphocytic leukemia (CLL).

NCT ID: NCT02969629 Completed - Clinical trials for Chronic Low Back Pain

The Effects of Apomorphine on Experimental and Clinical Pain in Patients With Chronic Radicular Pain

Start date: December 2012
Phase: Phase 4
Study type: Interventional

The study aimed to explore the effect of the dopamine agonist apomorphine on spontaneous pain intensity and evoked cold clinical and experimental pain in patients with lumbar radicular neuropathic pain (NP). Patients received either apomorphine or placebo in a randomized double-blinded manner.

NCT ID: NCT02968797 Recruiting - Apnea Clinical Trials

Clinical Comparative Study to Validate Performance of SafeSed Prototype Monitoring Endoscopy Under Sedation

SafeSed
Start date: September 1, 2016
Phase:
Study type: Observational

SafeSed prototype monitors respiratory parameters by tracking chest movements with optical and accelerometer markers. The respiratory parameters are compared to respiratory parameters measured by a spirometer and a capnograph.

NCT ID: NCT02968004 Active, not recruiting - Clinical trials for Pediatric Growth Hormone Deficiency

Safety and Efficacy Phase 3 Study of Long-acting hGH (MOD-4023) in Growth Hormone Deficient Children

Start date: December 2016
Phase: Phase 3
Study type: Interventional

This will be an open-label, randomized, multicenter, efficacy and safety study of weekly MOD-4023 compared to daily Genotropin therapy in pre-pubertal children with growth hormone deficiency.

NCT ID: NCT02967692 Active, not recruiting - Melanoma Clinical Trials

A Study of the Anti-PD1 Antibody PDR001, in Combination With Dabrafenib and Trametinib in Advanced Melanoma

COMBI-i
Start date: February 17, 2017
Phase: Phase 3
Study type: Interventional

To evaluate the safety and efficacy of the combination of an anti-PD-1 antibody (Spartalizumab (PDR001)), a BRAF inhibitor (dabrafenib) and a MEK inhibitor (trametinib) in unresectable or metastatic BRAF V600 mutant melanoma