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NCT ID: NCT03078881 Completed - Clinical trials for Crigler-Najjar Syndrome

Clinical Assessment Study in Crigler-Najjar Syndrome

LUSTRO
Start date: March 10, 2017
Phase:
Study type: Observational

This is a Pre-Phase 1 prospective, non-interventional clinical assessment study to evaluate Crigler-Najjar syndrome subjects requiring daily phototherapy, aged 1 year and older.

NCT ID: NCT03078569 Recruiting - Infertility, Female Clinical Trials

Transdermal Testosterone for Poor Responder Patients Undergoing Controlled Ovarian Stimulation Prior to IVF

Start date: March 2017
Phase: Phase 4
Study type: Interventional

This study evaluates the efficacy of pre- IVF treatment with transdermal testosterone to enhance ovarian response in poor responders. a randomized controlled trial with two groups, treatment group with transdermal testosterone before IVF treatment and a control group with no treatment.

NCT ID: NCT03078309 Recruiting - Clinical trials for Retinitis Pigmentosa

The Effects of Cannabis on Visual Functions in Healthy and Retinitis Pigmentosa Patients

Start date: September 1, 2018
Phase: Early Phase 1
Study type: Interventional

Medical Marijuana is used widely, and its effects on the visual system and the function of the retina have not been investigated thoroughly. Some evidence suggests that cannabinoids may be beneficial in certain degenerative diseases of the retina. The purpose of the study is 1. To determine whether cannabis derivatives affect the visual functions in healthy adults 2. To examine the effect of cannabis derivatives on the retina of retinitis pigmentosa patients

NCT ID: NCT03077100 Not yet recruiting - Pathogen Resistance Clinical Trials

Identification of Pathogens in the Neonatal Intensive Care Unit (NICU)

Start date: March 2017
Phase: N/A
Study type: Observational

To aim of this study is to identify the pathogens and their distribution in the NICU and to determine whether empirical antibiotics are suitable for the treatment of sepsis in the unit.

NCT ID: NCT03077074 Recruiting - Clinical trials for Changes in Functional MRI

Brain Responses to Visual Food Cues in Response to a Low Carbohydrate Diet

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The aim is to profile and elucidate the hormonal and neurological system interaction to food related behavior. The stimulus used will include visual and taste (gustatory) stimuli. The study will profile induced correlations of metabolic parameters, gut hormones and brain region (ROI - regions of interest) activation and interaction. In this study we will use fMRI (functional MRI) to compare brain responses in obese, normal-weight and reduced weight subjects. The food stimuli will be blocked into specific categories to allow for investigation of different responses to alternating energy density foods. The response will be tested prior to and following a brief low carbohydrate dietary regimen.

NCT ID: NCT03076515 Terminated - Acute Migraine Clinical Trials

Migraine Treatment With Nerivio Migra Neurostimulation Device

Start date: April 2, 2017
Phase: N/A
Study type: Interventional

This is a prospective, randomized, double-blind, sham controlled multi-center trial. Ratio between treatment and control groups will be 1:1, stratified by center and use of preventive medications.

NCT ID: NCT03076073 Completed - Obesity Clinical Trials

Ultrasonography of the Patellar Tendon and Achilles Tendon in Children Adolescent and Adults

Start date: May 20, 2017
Phase: N/A
Study type: Interventional

The aim of the current study is to evaluate the Patellar tendon and Achilles tendon structures among children, adolescents and adults with different weight status. That in order to improve our understanding on the impact of acute and overused loads on tendon structure; and, in developing strategies to reduce tendon's injuries following physical exercises.

NCT ID: NCT03075293 Not yet recruiting - Pain Clinical Trials

Pain Management of Children With Appendicitis in the Emergency Department (ER)

Start date: March 26, 2017
Phase: N/A
Study type: Observational

The aim of this retrospective study is to determine the percentage of children with appendicitis who were given analgesics or opioids in the ER, to reduce their pain.

NCT ID: NCT03075111 Completed - Fever Clinical Trials

Host-based Immunoassay for Differentiating Bacterial From Viral Infections (Post-marketing Study of ImmunoXpert™ - SPIRIT Study)

Start date: November 7, 2015
Phase:
Study type: Observational

This is a retrospective external field study of a novel in vitro diagnostic (IVD) assay (ImmunoXpert™). The study will involve reviewing the medical charts of about 4500 pediatric patients that were tested using ImmunoXpert™ as part of the routine workup for acute febrile illness. ImmunoXpert™ uses a computer algorithm to combine immunoassay measurements of three host immune proteins (TRAIL, IP-10, and CRP) present in human blood. The test is intended for use in conjunction with clinical assessments and other laboratory findings as an aid to differentiate bacterial from viral infection. Statistical analysis will be performed to compare the diagnostic accuracy of ImmunoXpert™ with that of current practice lab testing e.g., WBC, CRP, and PCT (whichever were taken as part of routine care) and clinical suspicion at time of requisition.

NCT ID: NCT03074123 Completed - Clinical trials for Adrenal Insufficiency

Cortisol Response to Low Dose Cosyntropin Stimulation Test in the Late Afternoon

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

Previous study showed that afternoon cosyntropin testing was associated with a sevenfold increased likelihood of failing the 1μg test. However, in that study, investigators used a 20.3 cm plastic tube, which might have led to uncompleted cosyntropin delivery. In ther current study investigators will study afternoon 1μg cosyntropin cortisol stimulation using a short 2.5 cm tube.