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NCT ID: NCT03738397 Completed - Atopic Dermatitis Clinical Trials

A Study to Compare Safety and Efficacy of Upadacitinib to Dupilumab in Adult Participants With Moderate to Severe Atopic Dermatitis

Heads Up
Start date: February 21, 2019
Phase: Phase 3
Study type: Interventional

This study will evaluate upadacitinib compared to dupilumab (Dupixent®) in adults with moderate to severe atopic dermatitis (AD) who are candidates for systemic therapy.

NCT ID: NCT03737734 Active, not recruiting - Skin Cancer Clinical Trials

Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia (DaRT)

Start date: December 31, 2018
Phase: N/A
Study type: Interventional

A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for superficial cutaneous, mucosal or soft tissue neoplasia

NCT ID: NCT03737110 Completed - Clinical trials for Recurrent Pericarditis

Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis

RHAPSODY
Start date: January 7, 2019
Phase: Phase 3
Study type: Interventional

The primary objective of this study was to assess the efficacy of rilonacept treatment in participants with recurrent pericarditis.

NCT ID: NCT03736525 Recruiting - Wellness Clinical Trials

DWELL: Design For Wellness - An Online Intervention To Create Healthier Home Environments

Start date: November 25, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

Design for wellness (DWELL) is an online Facebook intervention developed to effectively cause participants to design their home environments for wellness. Also, to improve health behaviors (specifically: healthy nutrition, physical activity, smoke free home and hygiene); to improve awareness of the importance of the environment in healthy behaviors; and to improve overall wellness. The research will follow qualitative methods in early stages for a deep understanding of participants' needs and inputs, complimented by a rigorous, quantitative approach using randomized controlled trail (RCT) for program evaluation. Participants are Israeli mothers to children up to 18 years old with Facebook profile, who are often in Israel responsible for household management and raising the family. The program will provide the participants with an accessible and convenient online setting for active and group oriented collaborative learning, in informal personalized environment. Motivating the participants to enhance their engagement in DWELL online community is expected to encourage the participants to design their home environment for wellness and improve their health behaviors and overall wellness.

NCT ID: NCT03735134 Not yet recruiting - Clinical trials for Myocardial Infarction

Colchicine in Periprocedural Myocardial Infarction: the Role of Alpha Defensin

Start date: November 2018
Phase: N/A
Study type: Interventional

The aim of this research is to study the effect of a loading dose of colchicine on the occurrence of periprocedural myocardial infarction (PPMI) in elective percutaneous coronary intervention.

NCT ID: NCT03734081 Suspended - Clinical trials for Overweight and Obesity

Safety and Feasibility Assessment of the Bio-electrical One Day Capsule System in Overweight and Class I Obese Participants

Start date: February 4, 2019
Phase: N/A
Study type: Interventional

The study represents the first effort to prospectively investigate the Melcap's bio-electrical ingestible ODC system in human. The study goal is to evaluate the safety and feasibility of GES treatment in stomach and in the small and large bowel during and following the ingestion of the bio-electrical capsule under tight and controlled conditions.

NCT ID: NCT03734029 Active, not recruiting - Breast Cancer Clinical Trials

Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed [DESTINY-Breast04]

Start date: December 27, 2018
Phase: Phase 3
Study type: Interventional

This study will compare DS-8201a to physician choice standard treatment. Participants must have HER2-low breast cancer that has been treated before. Participants' cancer: - Cannot be removed by an operation - Has spread to other parts of the body

NCT ID: NCT03733444 Terminated - Clinical trials for Idiopathic Pulmonary Fibrosis

A Clinical Study to Test How Effective and Safe GLPG1690 is for Participants With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard of Care

ISABELA2
Start date: November 5, 2018
Phase: Phase 3
Study type: Interventional

The main purpose of this study was to see how GLPG1690 works together with the current standard treatment on your lung function and IPF disease in general. The study also investigated how well GLPG1690 is tolerated (for example if you get any side effects while on study drug).

NCT ID: NCT03732677 Active, not recruiting - Clinical trials for Muscle Invasive Bladder Cancer

Durvalumab+ Gemcitabine/Cisplatin (Neoadjuvant Treatment) and Durvalumab (Adjuvant Treatment) in Patients With MIBC

NIAGARA
Start date: November 16, 2018
Phase: Phase 3
Study type: Interventional

A Global Study to Determine the Efficacy and Safety of Durvalumab in Combination with Gemcitabine+Cisplatin for Neoadjuvant Treatment and Durvalumab Alone for Adjuvant Treatment in Patients with Muscle-Invasive Bladder Cancer

NCT ID: NCT03731663 Completed - Clinical trials for Eating Habits and Behaviors, (UMLS)

The Effect of Exposure to Food in Social Networks on Food Cravings and External Eating

FEECAEE
Start date: April 12, 2018
Phase: N/A
Study type: Interventional

Background: Food practices are socially, culturally and historically embedded in everyday life. It is a common notion that people eat due to internal state of physiologic hunger but in fact the drive behind eating behaviors is much more complex. We eat, inter alia, because of our response to external cues such as the sight and smell of food, or external eating. Another related concept is food cravings: intense irresistible desires to consume a particular food that is distinct from hunger. Both external eating and food cravings have been associated with impulsivity, eating disorders and obesity. During recent decades the role of the media, and recently of the social media in our lives has grown significantly, and their influence on culture and society is now huge. A common activities on social media sites (SNS) is food viewing and posting pictures of tempting food, known as food porn. Food porn has been found to correlate with eating patterns and food-related attention and reward bias. The aim of this study is to conduct a controlled manipulation that may help us deduce causality as well as association. The investigators postulate that (1) viewing pictures of appetizing food will lead to higher rates of reported external eating and food craving than viewing pictures that are not food related; (2) Viewing these appetizing food pictures will lead participants to order different kinds of food and greater amounts; (3) The effect of viewing food pictures on external eating, food cravings and food orders will be greater for participants with high disturbed eating, then for participants without disturbed eating. Method: After providing informed consent, 150 female participants (aged 18-35) will self report on demographic variables, SNS food preoccupation and disturbed eating (EAT-26). They will then be randomly assigned to watch either a food porn or control video. They will complete measures of food cravings (FCQ-S) and external eating (DEBQ) after watching the video and asked to order food they would like to eat from a virtual menu.)