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NCT ID: NCT00367107 Not yet recruiting - Autism Clinical Trials

Autism in Adult Patients and the Effects on Caregivers

Start date: August 2008
Phase: N/A
Study type: Observational

Background: The number of adults with autism is expected to rise significantly in the near future, due to two main reasons: First, a dramatic increase in the estimates of the prevalence of autism starting in the mid 1980s; Second, the clinical diagnosis of autism was first introduced during the 1950s, and those diagnosed with autism back then are only now entering middle age. Few studies, however, have focused on the outcomes of adult autistic individuals, and very little is known about the course of autism in adulthood and on the familial burden resulting from caring for an autistic adult. We therefore propose to study adult outcomes in autism, and to examine the influence of raising an autistic individual on the parents. Working hypothesis and aims: The primary objectives of the study are: 1. Determine clinical status and functioning of autistic adults. 2. Study the influence of raising and caring for an individual with autism on the well-being of the parents.

NCT ID: NCT00351247 Not yet recruiting - Clinical trials for Myocardial Infarction

Postconditioning in Primary PCI and Direct Stenting

Start date: July 2006
Phase: N/A
Study type: Interventional

To determine the safety and efficacy of 2 vs 4 cycles of postconditioning method during primary PCI and direct stenting in acute MI, and to compared to primary PCI and direct stenting without the postconditioning.

NCT ID: NCT00347867 Not yet recruiting - IUGR Clinical Trials

Viagra for the Treatment of IUGR

Start date: July 2006
Phase: Phase 4
Study type: Interventional

It has been suggested that Viagra (or other drugs that inhibit PDE-5, the enzyme that normally inhibits blood vessels’ ability to expand) may have beneficial effects in hypertensive pregnancy and, possibly, preeclampsia.The benefits of Viagra were observed without any reduction in maternal blood pressure, thereby dissociating hypertension per se from the loss of NO (nitrous oxide) signaling in the uterine circulation.Following publications, suggesting that sildenafil citrate used as a therapeutic agent may improve myometrial perfusion in IUGR gestations by promoting myometrial small artery vasodilatation, decreasing peripheral resistance and increasing flow within the uteroplacental bed, we intend to administer this medication to parturients where intauterine growth restriction and pregnancy associated hypertension have been diagnosed in an attempt to induce vasodilatation and improved uteroplacental perfusion resulting in improved fetal growth.

NCT ID: NCT00334087 Not yet recruiting - Dental Caries Clinical Trials

The Relation Between Pregnancy,Birth Outcome, Feeding , Oral Hygiene Habits and Early Childhood Caries Development.

Start date: June 2007
Phase: N/A
Study type: Observational

- 200 children between ages 36 to 48 months will be invited for a regular dental examination - Parameters to be investigated 1. Pregnancy history 2. Birth outcome 3. Child's general health 4. Feeding habits 5. Oral hygiene habits 6. Dmft caries index 7. Congenital enamel defects

NCT ID: NCT00331656 Not yet recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure.

Start date: June 2008
Phase: Phase 4
Study type: Interventional

Non-invasive ventilation has become increasingly important in the management of patients with acute respiratory failure. One of its major goals is to prevent the need for invasive ventilation, which is associated with numerous complications. This study compares the usefulness and safety of two noninvasive techniques which are used in Medical practice: Noninvasive positive pressure ventilation using a face mask and extrathoracic biphasic ventilation using a cuirass. Each of these techniques has advantages and disadvantages and both may not suit all patients. It is therefore important to compare the two in terms of effectiveness in preventing invasive ventilation and their side effects profile, so that we can improve our understanding and expertise in the treatment of patients in respiratory failure.

NCT ID: NCT00326365 Not yet recruiting - Clinical trials for Mechanically Ventilated ICU Patients

Effect of Homeopathic Remedy Kalium Bichromicum on Viscosity and Amount of Sputum Mechanically Ventilated ICU Patients.

Start date: June 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the homeopathic remedy Kali Bichromium is effective in reducing the amount of tracheal secretions in patients intubated with a conventional endotracheal tube and receiving controlled mechanical ventilation in the ICU setting.

NCT ID: NCT00320840 Not yet recruiting - Preterm Infants Clinical Trials

Internal and Familial Resources and Motherhood. Follow Up of Mothers With Twins and Preterm Infants Versus Mothers With Single Full Term Infants

Start date: May 2006
Phase: N/A
Study type: Observational

To evaluate the contribution of internal and familial resources on the development of motherhood in a population of mothers having preterm twin infants and comparing this population to a population of mothers giving birth to single (or twins) full term infants.

NCT ID: NCT00320437 Not yet recruiting - Anxiety Clinical Trials

Intergenerational Transmission of Terror

Start date: May 2007
Phase: Phase 1
Study type: Observational

Our aim is examine avenues by which mothers can transmit their trauma to their children.

NCT ID: NCT00318162 Not yet recruiting - Clinical trials for Pervasive Developmental Disorder

Trial of Low-Dose Naltrexone for Children With Pervasive Developmental Disorder (PDD)

Start date: n/a
Phase: Phase 1/Phase 2
Study type: Interventional

This study will examine the effects of low-dose naltrexone (LDN) on children with autistic spectrum disorders. The investigators hope to show a positive effect on social functioning and language.

NCT ID: NCT00305513 Not yet recruiting - Clinical trials for Cerebrovascular Accident

Effectiveness of Rehabilitation on the Recovery of Patients Post Right Stroke With Unilateral Spatial Neglect

Start date: n/a
Phase: Phase 2
Study type: Interventional

Unilateral spatial neglect (USN) is believed to be a disorder of attention, characterized by impairment in the ability to perceive or respond to stimuli presented to the contralesional space, and which is not attributable to significant sensory or motor deficits. USN has serious consequences for rehabilitation and long term disabilities. Efforts have been made to clarify both the theoretical basis of this phenomenon and the rehabilitation methods that will be best in improving function. The purpose of this study is to try and contribute to both efforts by examining treatment effectiveness of two methods; one targeting general arousal (phasic alerting), and the other targeting increasing awareness to left side stimuli and habit changes. Functional neuroimaging methods (PET [positron emission tomography] and fMRI [functional magnetic resonance imaging]) have been applied to understand the functional anatomy of the brain during mental processes. Only a few attempts have been made to use functional neuroimaging in patients with neurological deficits such as USN, usually speculations are made based on findings with healthy participants to explain this disorder. This study's aim is to examine the functional reorganization of the attentional network in the brain of USN patients while performing visual tasks, by means of functional neuroimaging techniques, in light of specific rehabilitation techniques. Patients will be examined before and after 3 weeks of rehabilitation both using standardized neurobehavioral tests and PET imaging procedures.