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NCT ID: NCT01617668 Completed - Breast Cancer Clinical Trials

A Randomized, Phase 2, Neoadjuvant Study of Weekly Paclitaxel With LCL161 in Patients With Triple Negative Breast Cancer

Start date: August 2012
Phase: Phase 2
Study type: Interventional

To assess whether adding LCL161 to weekly paclitaxel enhances the efficacy of paclitaxel in women with triple negative breast cancer whose tumors are positive for a defined pattern of gene expression

NCT ID: NCT01610037 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Comparison of Long-term Safety of the Combination Product QVA149A Against Placebo and Standard of Care Treatment in Chronic Obstructive Pulmonary Disease Patients With Moderate to Severe Airflow Limitation

Start date: October 2012
Phase: Phase 3
Study type: Interventional

The study will assess the long-term safety of the fixed combination product QVA149 versus placebo and a standard of care treatment (tiotropium) in Chronic Obstructive Pulmonary Disease (COPD) patients with moderate to severe airflow limitation.

NCT ID: NCT01608789 Completed - Clinical trials for Stress Urinary Incontinence

Virtue® European Study

Start date: August 27, 2012
Phase: N/A
Study type: Interventional

This study is a prospective, single arm, non-randomized, multi-center clinical study that will be conducted in Europe. It is designed to assess efficacy and safety of the Virtue® Male Sling in post-prostatectomy urinary incontinence.

NCT ID: NCT01607957 Completed - Colorectal Cancer Clinical Trials

Study of TAS-102 in Patients With Metastatic Colorectal Cancer Refractory to Standard Chemotherapies

RECOURSE
Start date: June 17, 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy and safety of TAS-102 versus placebo in patients with refractory metastatic colorectal cancer.

NCT ID: NCT01606995 Completed - Atrial Fibrillation Clinical Trials

Xarelto for Prevention of Stroke in Patients With Atrial Fibrillation

XANTUS
Start date: June 12, 2012
Phase:
Study type: Observational

This is an international observational study in patients with non-valvular atrial fibrillation who are prescribed rivaroxaban under routine treatment conditions to prevent stroke or non-central nervous system systemic embolism.

NCT ID: NCT01605227 Completed - Prostate Cancer Clinical Trials

Study of Cabozantinib (XL184) Versus Prednisone in Men With Metastatic Castration-resistant Prostate Cancer Previously Treated With Docetaxel and Abiraterone or MDV3100

COMET-1
Start date: July 2012
Phase: Phase 3
Study type: Interventional

This study will evaluate the effect of cabozantinib compared to prednisone on overall survival in men with previously treated metastatic castration-resistant prostate cancer with bone-dominant disease who have experienced disease progression on docetaxel-containing chemotherapy and abiraterone or MDV3100.

NCT ID: NCT01604278 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Efficacy, Safety and Tolerability of the Co-administration of NVA237 Plus Indacaterol Once Daily Versus Indacaterol Once Daily in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

GLOW6
Start date: May 2012
Phase: Phase 3
Study type: Interventional

This study assessed the efficacy, safety and tolerability of the co-administration of NVA237 plus indacaterol taken once daily versus indacaterol taken once daily in patients with moderate to severe Chronic Obstructive Pulmonary Disease.

NCT ID: NCT01600482 Completed - Clinical trials for Coronary Artery Disease

Clinical Investigation for Safety and Efficacy Study of CELT ACD Arterial Closure Device

Start date: May 2012
Phase: N/A
Study type: Interventional

The objective of the CELT ACD® Vascular Closure Device study is to evaluate the safety and effectiveness of the CELT ACD® device to achieve hemostasis of the common femoral artery access site in patients on anticoagulation who are undergoing a percutaneous coronary intervention (PCI) procedure using either a 6F or 7F procedural sheath.

NCT ID: NCT01599988 Completed - Enteral Feeds Clinical Trials

Study to Compare Milk Protein Isolate (MPI) With Caseinate in Terms of Protein Utilization

Start date: October 2011
Phase: Phase 2/Phase 3
Study type: Interventional

The Clinical Research Ethics Committee, Cork comprises of faculty representatives, external representatives, legal representatives and appropriate individuals and ex-officio administrative members with needed expertise. Ethics Committee members, including the Chair, are appointed by the Head of College, University College Cork, Medical School. The Ethics Committee meets once a month.

NCT ID: NCT01599650 Completed - Clinical trials for Branch Retinal Vein Occlusion

Efficacy and Safety of Ranibizumab With or Without Laser in Comparison to Laser in Branch Retinal Vein Occlusion

BRIGHTER
Start date: May 2012
Phase: Phase 3
Study type: Interventional

This study will generate comparative data for 0.5-mg ranibizumab using PRN dosing administered with or without adjunctive laser treatment versus laser photocoagulation (the current standard of care) up to Month 6 in patients with visual impairment due to ME secondary to BRVO. Additionally the results of this study will provide long-term (24-month) safety and efficacy data for ranibizumab, administered with or without adjunctive laser treatment in this indication.