Clinical Trials Logo

Filter by:
NCT ID: NCT00601172 Completed - Clinical trials for Nausea and Vomiting, Chemotherapy-Induced

A Study Of IV Casopitant For The Prevention Of Chemotherapy Induced Nausea And Vomiting.

Start date: March 10, 2008
Phase: Phase 3
Study type: Interventional

This a Phase III trial designed to determine if IV casopitant plus dexamethasone and ondansetron is more effective in the prevention of vomiting and nausea then dexamethasone and ondansetrone alone following the administration of moderately emetogenic oxaliplatin-based chemotherapy.

NCT ID: NCT00600340 Completed - Clinical trials for Metastatic Breast Cancer

2-arm Trial of Paclitaxel Plus Bevacizumab vs. Capecitabine Plus Bevacizumab

TURANDOT
Start date: April 2008
Phase: Phase 3
Study type: Interventional

First-line treatment of patients with locally recurrent or metastatic, HER2-negative breast cancer who have not received prior chemotherapy for locally recurrent or metastatic disease.

NCT ID: NCT00599196 Completed - Clinical trials for Early Stage Parkinson's Disease

An Open-Label Extension Trial to Assess the Safety of Long-Term Treatment of Rotigotine in Early-Stage Parkinson's Disease

Start date: August 2002
Phase: Phase 3
Study type: Interventional

The objective of this open-label extension is to assess the safety and tolerability of long-term treatment of the rotigotine patch in subjects with early-stage idiopathic Parkinson's disease

NCT ID: NCT00598442 Completed - Anemia Clinical Trials

Safety and Efficacy of Peginesatide for the Treatment of Anemia in Participants With Chronic Renal Failure Not on Dialysis

PEARL 2
Start date: November 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the safety and efficacy of peginesatide for the treatment of anemia in participants with chronic kidney disease, who are not on dialysis and not on erythropoiesis stimulating agent (ESA) treatment.

NCT ID: NCT00589914 Completed - Schizophrenia Clinical Trials

Comparison of Paliperidone Palmitate and RISPERDAL CONSTA in Patients With Schizophrenia

Start date: March 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate the effectiveness of paliperidone palmitate in patients with Schizophrenia.

NCT ID: NCT00583830 Completed - Clinical trials for Non Small Cell Lung Cancer

A Study of Mapatumumab in Combination With Paclitaxel and Carboplatin in Subjects With Non-small Cell Lung Cancer

NSCLC
Start date: January 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy (disease response) and safety of mapatumumab in combination with carboplatin and paclitaxel as first line therapy in subjects with advanced non-small cell lung cancer (NSCLC).

NCT ID: NCT00578227 Completed - Clinical trials for Infections, Papillomavirus

Evaluation of Safety and Immunogenicity of Co-administering Human Papillomavirus Vaccine With Another Vaccine in Healthy Female Subjects

Start date: December 15, 2007
Phase: Phase 3
Study type: Interventional

Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Vaccination of pre-teens and adolescents, ideally before sexual debut and thus before exposure to oncogenic HPV, is a rational strategy for prevention of cervical cancer, and so HPV vaccination could complement the existing pre-adolescent/adolescent vaccination programs. Therefore, this Phase IIIb study is designed to evaluate the safety and immunogenicity of co-administering a commercially available vaccine with GSK Biologicals' HPV-16/18 L1 AS04 (Cervarix ®) vaccine as compared to the administration of either vaccine alone. This Protocol Posting has been updated in order to comply with the FDA AA, Sept 2007.

NCT ID: NCT00577460 Completed - Parkinson Disease Clinical Trials

Long-term Safety Study of Open-label Pramipexole ER in Patients With Advanced PD

Start date: December 2007
Phase: Phase 3
Study type: Interventional

The general aim of this study is to obtain long-term safety and tolerability data on pramipexole extended release (ER), in daily doses from 0.375mg to 4.5mg once daily (qd), in patients who have previously completed a pramipexole double-blind study in advanced Parkinson's disease (PD) (248.525 trial).

NCT ID: NCT00575588 Completed - Type 2 Diabetes Clinical Trials

52-week add-on to Metformin Comparison of Saxagliptin and Sulphonylurea, With a 52-week Extension Period

Start date: December 2007
Phase: Phase 3
Study type: Interventional

Saxagliptin is a new investigational medication being developed for treatment of type 2 diabetes. This study is designed to assess the efficacy and tolerability of saxagliptin in addition to metformin and compare to sulphonylurea in addition with metformin.

NCT ID: NCT00574873 Completed - Clinical trials for Chronic Myeloid Leukemia

Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML

Start date: February 5, 2008
Phase: Phase 3
Study type: Interventional

Two-arm, randomized, open-label trial designed to evaluate the efficacy and safety of bosutinib alone compared to imatinib alone in subjects newly diagnosed with chronic phase Chronic Myelogenous Leukemia (CML). The primary endpoint is cytogenetic response rate at one year.