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NCT ID: NCT00698763 Completed - Stroke Clinical Trials

Effects of Oral Levosimendan on Ambulatory Electrocardiographic Variables

Electro
Start date: August 2008
Phase: Phase 2
Study type: Interventional

The primary objective is to explore the safety of low doses of oral levosimendan in patients with recent history of an ischaemic cerebrovascular event (stroke or TIA). The main focus will be on the evaluation of proarrhythmic potential of the different dose regimens.

NCT ID: NCT00696657 Completed - Clinical trials for Diabetes Mellitus, Type 2

A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and Liraglutide

Start date: June 3, 2008
Phase: Phase 2
Study type: Interventional

This trial was conducted in Europe,Asia and Africa. Study participants were randomised evenly to treatment with semaglutide (0.1 mg QW - 1.6 mg QW, 6 treatment arms, placebo or liraglutide (1.2 mg QD, or 1.8 mg QD).Treatment allocation to semaglutide or placebo was double-blind, whereas liraglutide treatment was administered open-label.Primary efficacy parameter was HbA1c and the treatment duration was 12 weeks.

NCT ID: NCT00696345 Completed - Colorectal Cancer Clinical Trials

Detection of Colorectal Cancer in Peripheral Blood by Septin 9 DNA Methylation Assay

Start date: January 2005
Phase: N/A
Study type: Observational

Epigenomics is developing a colon cancer screening assay based on differential methylation of specific CpG sites for the detection of early stage disease. A genome-wide methylation analysis and oligonucleotide array study using DNA from various stages of colon cancer and normal tissue have been completed to obtain candidate CpG markers. Based on results obtained in the above studies, Epigenomics has moved to the final stages of feasibility with a specific, highly sensitive real-time marker assay that is able to detect colon cancer DNA in blood plasma.

NCT ID: NCT00696332 Completed - ALS Clinical Trials

Talampanel for Amyotrophic Lateral Sclerosis (ALS)

ALS
Start date: September 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy, tolerability and safety of oral administration of talampanel compared to a placebo in subjects with ALS.

NCT ID: NCT00694382 Completed - Cancer Clinical Trials

Evaluation of AVE5026 in the Prevention of Venous Thromboembolism in Cancer Patients Undergoing Chemotherapy

SAVE-ONCO
Start date: June 2008
Phase: Phase 3
Study type: Interventional

The primary objective was to compare the efficacy of once daily subcutaneous injections of Semuloparin sodium (AVE5026) with placebo in the prevention of venous thromboembolism [VTE] in cancer patients at high risk for VTE and who were undergoing chemotherapy. The secondary objectives were to evaluate the safety of Semuloparin sodium (AVE5026), to document Semuloparin sodium (AVE5026) exposures, to try identifying a metagene predictor of VTE and to assess the survival status at one year in this population.

NCT ID: NCT00693381 Completed - Clinical trials for Kidney Transplantation

Mycophenolate Mofetil (MMF) Discontinuation From a Tacrolimus/MMF/Steroid Triple Regimen After Kidney Transplantation

DISTAMP
Start date: February 2003
Phase: Phase 3
Study type: Interventional

Patients after kidney transplantation received immunosuppression by Tacrolimus, MMF and steroids. In one half of the patients after 7 weeks MMF was reduced by half, and after 12 weeks it was stopped. For the others MMF remained at initial dose.

NCT ID: NCT00692874 Completed - Prostate Cancer Clinical Trials

Quality of Life Analysis of Treatment in Patients With Prostate Cancer on Adjuvant Zoladex Therapy

AZTEK EXT
Start date: June 2008
Phase: N/A
Study type: Observational

This is an open label, non-interventional quality of life analysis for Zoladex treated prostate cancer patients by investigator's questionnaire

NCT ID: NCT00692289 Completed - Breast Cancer Clinical Trials

Quality of Life Analysis of Arimidex Treatment in Postmenopausal Patients With Breast Cancer

RADAR II E
Start date: June 2008
Phase: N/A
Study type: Observational

This is an open label, non-interventional quality of life analysis for Arimidex treated postmenopausal patients in early breast cancer by investigator's questionnaire

NCT ID: NCT00691483 Completed - Smoking Cessation Clinical Trials

Randomized Study Comparing the Efficacy and Safety of Varenicline Tartrate to Placebo in Smoking Cessation When Subjects Are Allowed to Set Their Own Quit Date

Start date: September 2008
Phase: Phase 4
Study type: Interventional

The hypothesis is that varenicline will be effective (compared with placebo) for smoking cessation when subjects are allowed to set their own quit date within the first 5 weeks of treatment.

NCT ID: NCT00689338 Completed - Clinical trials for Invasive Candidiasis

Anidulafungin Candidemia/Invasive Candidiasis Intensive Care Study

ICE
Start date: July 2008
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy and safety of anidulafungin in the treatment of systemic fungal infections in intensive care and critical care unit patients.