Clinical Trials Logo

Filter by:
NCT ID: NCT00334152 Completed - Clinical trials for Postoperative Nausea and Vomiting

Casopitant And ZOFRAN To Prevent Post Operative Nausea And Vomiting In Women

Start date: March 2006
Phase: Phase 3
Study type: Interventional

This study is being conducted to see if adding GW679769 (casopitant) to ZOFRAN will significantly decrease the number of patients who experience nausea and vomiting after surgery.

NCT ID: NCT00334035 Completed - Schizophrenia Clinical Trials

Antipsychotic Therapy and First Episode

Start date: August 2003
Phase: Phase 4
Study type: Interventional

For schizophrenic patients who remained in remission while on maintenance medication, there may come a point in time when the relative risk for relapse become so low that discontinuation of therapy can be considered. This study is to investigate whether that point in time is reached in 12 months following the first episode illness. Moreover, it also aims to identify other predictors of relapse as well as to evaluate the costs and benefits of maintenance therapy.

NCT ID: NCT00327535 Completed - Anemia Clinical Trials

A Study of Mircera in Anemic Patients With Non-Small Cell Lung Cancer Receiving First Line Chemotherapy.

Start date: May 2006
Phase: Phase 2
Study type: Interventional

This 4 arm study will assess the optimal starting dose of Mircera in the treatment of anemia in patients with non-small cell lung cancer receiving first line myelosuppressive chemotherapy. Patients will be randomized to receive either Mircera 6.3 micrograms/kg, 9 micrograms/kg or 12 micrograms/kg s.c. every 3 weeks or darbepoetin alfa according to the approved local label (either 6.75 micrograms/kg s.c. every 3 weeks, or 2.25 micrograms/kg every week). The anticipated time on study treatment is <3 months and the target sample size is 100-500 individuals.

NCT ID: NCT00326248 Completed - Clinical trials for Nausea and Vomiting, Postoperative

Casopitant (Oral) And ZOFRAN To Prevent Postoperative Nausea And Vomiting In Women

Start date: March 2006
Phase: Phase 3
Study type: Interventional

This study is being conducted to see if adding GW679769 (casopitant) to ZOFRAN will significantly decrease the number of patients who experience nausea and vomiting after surgery.

NCT ID: NCT00323661 Completed - Clinical trials for Cardiac Pacing, Artificial

Closed Loop Stimulation, Cognitive Performance, and Quality of Life in Pacemaker Patients

COGNITION
Start date: May 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the influence of accelerometer-based rate adaptation and Closed Loop Stimulation on cognitive performance and quality of life in pacemaker patients.

NCT ID: NCT00322452 Completed - Clinical trials for Non-Small Cell Lung Cancer

First Line IRESSAâ„¢ Versus Carboplatin/Paclitaxel in Asia

IPASS
Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare gefitinib with carboplatin / paclitaxel doublet chemotherapy given as first line treatment in terms of progression free survival in selected NSCLC patients with the objective of demonstrating non-inferiority.

NCT ID: NCT00321919 Completed - Anemia Clinical Trials

A Study of Treatment With NeoRecormon (Epoetin Beta) in Patients With Chronic Renal Anemia

Start date: July 2000
Phase: Phase 3
Study type: Interventional

This study will evaluate whether anemia prevention with NeoRecormon has an additional impact on reducing cardiovascular risk over conventional anemia treatment in patients mostly with stage IV chronic kidney disease and renal anemia. The anticipated time on study treatment is 2+ years and the target sample size is 500+ individuals.

NCT ID: NCT00320450 Completed - Clinical trials for Arthritis, Rheumatoid

SB-681323 In Subjects With Rheumatoid Arthritis

Start date: November 2005
Phase: Phase 2
Study type: Interventional

The purpose of this research is to find out how effective and safe SB-681323 will be in the treatment of RA when it is added to standard anti-rheumatic treatments.

NCT ID: NCT00319761 Completed - IGA Nephropathy Clinical Trials

Calcitriol in the Treatment of Immunoglobulin A (IgA) Nephropathy

Start date: May 2006
Phase: Phase 4
Study type: Interventional

Immunoglobulin A (IgA) nephropathy is the most common type of primary glomerulonephritis in the world. A wealth of literature suggests that vitamin D and its analogs have profound effects on immune system function and glomerular mesangial cell proliferation. Calcitriol, an active form of vitamin D, is commonly used for the treatment of secondary hyperparathyroidism in patients with advanced chronic kidney diseases. Therefore, the investigators plan to conduct a open-label single-arm study to evaluate the safety and efficacy of calcitriol in the treatment of IgA nephropathy. Ten patients with biopsy-proven IgA nephropathy and persistent proteinuria despite conventional therapy will be recruited. They will be treated with calcitriol for 12 weeks. Proteinuria, renal function, serum and urinary inflammatory markers will be monitored. This study will explore the potential anti-proteinuric and anti-inflammatory effects of calcitriol in the treatment of IgA nephropathy, which is a major cause of dialysis-dependent renal failure.

NCT ID: NCT00319254 Completed - Breast Neoplasms Clinical Trials

Study Evaluating SKI-606 (Bosutinib) In Subjects With Breast Cancer

Start date: May 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if SKI-606 (Bosutinib) is effective in the treatment of advanced or metastatic breast cancer. Patients must have current Stage IIIB, IIIC or IV breast cancer and have progressed after 1 to 3 prior chemotherapy regimens.