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NCT ID: NCT00799903 Completed - Atherosclerosis Clinical Trials

The Stabilization of Atherosclerotic Plaque by Initiation of Darapladib Therapy Trial

STABILITY
Start date: December 2008
Phase: Phase 3
Study type: Interventional

This study will test whether darapladib can safely lower the chances of having a cardiovascular event (such as a heart attack or stroke) in people with coronary heart disease.

NCT ID: NCT00796679 Completed - Clinical trials for Chronic Kidney Disease

Oral Paricalcitol in Stage 3 - 5 Chronic Kidney Disease

Start date: October 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to test the hypothesis that selective vitamin D receptor activation reduces left ventricular hypertrophy and ameliorates inflammation and atherosclerosis in stage 3 -5 chronic kidney disease.

NCT ID: NCT00796653 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Safety and Efficacy of BI 1744 CL in Patients With Chronic Obstructive Pulmonary Disease II

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to assess the long-term efficacy and safety of once daily treatment of BI 1744 CL inhalation solution (5 and 10 mcg) delivered via the Respimat® inhaler, in patients with COPD.

NCT ID: NCT00794157 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Confirmatory Study of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Start date: November 2008
Phase: Phase 3
Study type: Interventional

This study was designed to provide pivotal confirmation of efficacy and safety data for 2 doses of indacaterol (150 and 300 µg once daily [od]) in patients with moderate to severe chronic obstructive pulmonary disease (COPD). Data from this study will be used for the registration of indacaterol in Japan.

NCT ID: NCT00793624 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Safety and Efficacy of BI 1744 CL in Patients With Chronic Obstructive Pulmonary Disease I

Start date: February 2009
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to assess the long-term efficacy and safety of once daily treatment of BI 1744 CL inhalation solution (5 and 10 mcg) delivered via the Respimat® inhaler, in patients with COPD.

NCT ID: NCT00791778 Completed - Ovarian Neoplasms Clinical Trials

Comparison of Nexavar/Placebo as Maintenance Therapy for Patients With Advanced Ovarian or Primary Peritoneal Cancer

Start date: November 2008
Phase: Phase 2
Study type: Interventional

Comparison of Nexavar with a placebo as maintenance therapy for patients with advanced Ovarian or primary Peritoneal cancers in complete remission following surgery and one regimen of chemotherapy.

NCT ID: NCT00790920 Completed - Stroke Clinical Trials

Efficacy and Safety Study of Desmoteplase to Treat Acute Ischemic Stroke

DIAS-3
Start date: December 2008
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine whether desmoteplase is effective and safe in the treatment of patients with acute ischaemic stroke when given within 3-9 hours from onset of stroke symptoms.

NCT ID: NCT00790036 Completed - Clinical trials for Diffuse Large B-cell Lymphoma

Phase III Study of RAD001 Adjuvant Therapy in Poor Risk Patients With Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 Versus Matching Placebo After Patients Have Achieved Complete Response With First-line Rituximab-chemotherapy

PILLAR2
Start date: July 2009
Phase: Phase 3
Study type: Interventional

Phase III study of RAD001 adjuvant therapy in poor risk patients with Diffuse Large B-Cell Lymphoma (DLBCL) of RAD001 versus matching placebo after patients have achieved complete response with first-line rituximab-chemotherapy

NCT ID: NCT00785785 Completed - Clinical trials for Gastrointestinal Stromal Tumor (GIST)

A Study of Nilotinib Versus Imatinib in GIST Patients

ENESTg1
Start date: March 2009
Phase: Phase 3
Study type: Interventional

This study will evaluate efficacy and safety of nilotinib versus imatinib in adult patients with unresectable or metastatic gastrointestinal stromal tumors (GIST).

NCT ID: NCT00784264 Completed - Atherosclerosis Clinical Trials

A Study on Intima Media Thickness (IMT) in Middle-aged Subjects

IMT
Start date: October 2008
Phase: N/A
Study type: Observational

This is an observational study to measure the thickness of artery walls in the neck (intima media thickness IMT) by ultrasound examination in middle-aged subjects with central obesity. The purpose of this study is to obtain local data how common asymptomatic atherosclerosis is, and to investigate the association between Cardiovascular Disease risk factors and intima media thickness (IMT) in the Hong Kong population. Results from this study may enhance the public awareness of asymptomatic atherosclerosis and understand its role in the development of Cardiovascular Disease in Hong Kong.