Clinical Trials Logo

Filter by:
NCT ID: NCT03164096 Recruiting - Clinical trials for Anesthesia, Obstetrical

The Effect of Some Parturients' Characteristics on Sensory Block Level After Spinal Anesthesia

Start date: June 1, 2017
Phase: Phase 4
Study type: Interventional

Although the exact mechanism remains unknown, the association of pregnancy and decreased local anesthetic requirement is clear. demonstrated that more local anesthetic is required for cesarean section under combined spinal-epidural anesthesia in preterm compared with term patients.

NCT ID: NCT03163238 Recruiting - Clinical trials for Cardiac Surgical Procedures

Dexmedetomidine and the Inflammatory Response in Pediatric Cardiac Surgery

Start date: May 30, 2017
Phase: Phase 2
Study type: Interventional

Cardiopulmonary bypass-assisted surgery initiates a systemic inflammatory response induced by extrinsic (e.g. anesthesia, contact activation within the extracorporeal circuit, endotoxemia) and intrinsic (e.g. tissue damage, endothelial cell activation, ischemia-reperfusion injury of myocardium) factors. This may either be mild or lead to a more severe clinical condition. Inflammation after pediatric open heart surgery is a parameter affecting also duration of mechanical ventilatory support. Dexmedetomidine use was associated with a reduced increase in plasma IL-1, IL-6, TNF-a, and INF-g levels

NCT ID: NCT03159793 Recruiting - Anxiety Clinical Trials

Evaluation of Different Modelling Techniques on Child Anxiety (RCT)

Start date: December 15, 2017
Phase: N/A
Study type: Interventional

A huge number of children suffer from anxiety during their dental treatment especially those who did not receive any type of behavior management during their first dental visit. This will result in a more complicated treatment sessions for the children, dentist and the parents. Fear and anxiety control is the key to change the resistant nature of the anxious patients and also allow them to receive the proper treatment they require. From the point of view that there is no difference between the techniques effectiveness, evaluation of two modelling techniques (live modelling and filmed modelling versus no modelling) for children anxious behavior management during the dental treatment will be performed.

NCT ID: NCT03158168 Recruiting - Warts Clinical Trials

Intralesional Candidal Antigen Versus Intralesional Zinc Sulphate in Treatment of Cutaneous Warts

Start date: March 1, 2018
Phase: Phase 3
Study type: Interventional

Warts are common and infectious viral diseases of the skin and are prevalent worldwide. Warts are caused by the human papilloma virus (HPV), which has more than 100 strains; some of them are known to be premalignant .Although warts can appear at any age, they are more common in children and adolescents. The prognosis of warts cannot be predicted. In some patients they may spontaneously disappear, whereas others show persistence and progression with spreading to other body sites, leading to physical and emotional distress to the patients. [ 1 ].

NCT ID: NCT03156972 Recruiting - Clinical trials for Rheumatic Heart Disease

Speckle Tracking for Timing of Surgical Operation in Severe Mitral Regurge

Start date: April 1, 2017
Phase: N/A
Study type: Interventional

Rhumatic heart disease patients with mitral regurge untile know had adibat for timming of surgical interferance our study aim to solve this problme using a new technic in echocardiography called speckle tracking which is more accurate in estimating a changes occure to myocyte of the heart and so chosing the proper time for surgery

NCT ID: NCT03154242 Recruiting - Clinical trials for Carcinoma, Non-Small-Cell Lung

Effect of Genetic Polymorphisms on Platinum Based Chemotherapy in Non Small Cell Lung Cancer

Start date: March 20, 2017
Phase: N/A
Study type: Observational

This Study evaluate the effect of Polymorphism in the Excision repair cross-complementing group 5 (ERCC5) (rs1047768 and rs751402) gene on the clinical outcome of Platinum-based regimens used in the treatment of Non-Small Cell Lung Cancer (NSCLC) patients

NCT ID: NCT03151668 Recruiting - Septic Shock Clinical Trials

Effect of Dexmedetomidine on Perfusion Index and Microcirculation in Severe Sepsis and Septic Shock Patients

Start date: January 4, 2017
Phase: Phase 3
Study type: Interventional

Septic shock is one of the major causes of death worldwide with in-hospital mortality rates varying between (11.9% to 47.2 %). Alterations in microcirculatory blood flow were associated with high risk of organ dysfunction and death. Experimental studies on septic rats revealed that dexmedetomidine treatment can effectively reduce the generation of inflammatory mediators and yields beneficial effects on endotoxemic animals' microcirculation.

NCT ID: NCT03151213 Recruiting - Clinical trials for Hepatocellular Cancer

Effect of Pregabalin on the Postoperative Analgesia in RFA of Focal Lesions in the Liver

pregabalin
Start date: May 1, 2017
Phase: Phase 4
Study type: Interventional

The study aimed to investigate the preemptive analgesia efficacy of of preemptive pregabalin for the postoperative pain management after radiofrequency ablation (RFA) of liver cancer.

NCT ID: NCT03150745 Recruiting - Cervical Dysplasia Clinical Trials

Diagnosis of Cervical Lesions in Women With Unhealthy Looking Cervix

Start date: May 2016
Phase: N/A
Study type: Interventional

Endocervix (cervical canal) is the cavity of the cervix and connects the external os with the internal os. It is fusiform in shape and has posterior and anterior oblique longitudinal ridges, the plicae palmatae. These are not exactly apposed but inter-lock like a zipper so that the canal is kept closed. The original squamous epithelium is clearly identified as a smooth, usually featureless covering of the cervix; its uniform pink color contrasts with the redness of the original columnar epithelium. It joins the latter at the original squamocolumnar junction. Many clinicians encounter cervical lesions that may or may not be associated with cytologic abnormalities. Such abnormalities as ectropion, Nabothian cysts, and small cervical polyps are quite benign and need not generate concern for patient or clinician, whereas others, including those associated with a history of exposure to diethylstilbestrol, cervical inflammation, abnormal cervical cytology, and postcoital bleeding, should prompt additional evaluation. Further, in some patients, the cervix may be difficult to visualize. Several useful clinical suggestions for the optimal examination of the cervix are presented.

NCT ID: NCT03148158 Recruiting - Pain, Postoperative Clinical Trials

Assessment Of Bladder Tumors Stage And Grade By Outpatient Flexible Cystoscopy Performed By Urology Resident

Start date: January 15, 2018
Phase: N/A
Study type: Observational

This will be a prospective trial comparing the perspective gross morphological of bladder tumor assessment done by outpatient flexible cystoscopy performed by resident, inpatient rigid cystoscopy done by senior staff and their prediction of the degree of invasion of bladder tumor plus the prediction of the grade compared with the standard pathological result. Also, assessment of the patient reported outcomes after both flexible and rigid cystoscopy will be done. In the long run of the study, the prognostic gross morphology with recurrence, progression and cancer specific survival will be assessed.